Evaluating shoulder joint contact patterns in osteoarthritis patients
Official title: In-vivo Evaluation of Glenohumeral Joint Contact Patterns in Osteoarthritic Glenoids
Run by Universitaire Ziekenhuizen KU Leuven · NCT06154694 · Data updated 2026-11-12
This study looks at how the shoulder joint works in people with arthritis before and after they have shoulder replacement surgery to see if it can help improve their recovery.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 156 (estimated) |
| Sponsor | Universitaire Ziekenhuizen KU Leuven Academic / other |
| Locations | 1 site (Leuven, Vlaams-Brabant) |
| Status | Recruiting |
| Started | November 3, 2021 |
| Main results expected | July 1, 2050 |
| Study ends | July 1, 2050 |
| Registry record updated | April 2, 2026 |
| Trial ID | NCT06154694 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include patients with glenohumeral osteoarthritis who are scheduled for anatomic shoulder arthroplasty.
✕Probably not a fit
Patients with postoperative complications such as stiffness, pain, or instability will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to assess the glenohumeral contact patterns in patients with osteoarthritic glenoids before and after total shoulder arthroplasty (TSA). It focuses on understanding the relationship between glenoid morphology, humeral head migration, and the incidence of component loosening post-surgery. By utilizing stereo radiographic EOS measurements, the study seeks to identify the mechanical factors contributing to complications in TSA. The findings could provide insights into improving surgical outcomes for patients with shoulder osteoarthritis.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical techniques and outcomes for patients undergoing shoulder arthroplasty.
How similar studies have gone: While the specific approach of this study may be novel, similar studies have indicated that understanding joint mechanics can lead to improved surgical outcomes.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: OA patients group * Patients with glenohumeral osteoarthritis planned for anatomic shoulder arthroplasty in the University Hospitals Leuven, Belgium * Complete patient informed consent * Pain free at the time of EOS imaging Healthy control group * Healthy adult volunteers with no history of shoulder pain or trauma * Confirmation of the physician, that subject's clinical evaluation and CT scan did not show any abnormalities * Complete informed consent Revised TSA group * Patients with glenohumeral osteoarthritis who received an anatomic shoulder arthroplasty at the University Hospitals Leuven within the past 30 years, and who have been revised for loosening of the glenoid component. * At least 1 postoperative CT scan available Exclusion Criteria: Only patients with a functional TSA will be included, so patients with postoperative stiffness, pain, instability or pseudoparalysis will be excluded.
Where it's running
-
UZ Leuven
Leuven, Vlaams-Brabant, Belgium Recruiting
Study contacts
- Principal investigator: Filip Verhaegen — Universitaire Ziekenhuizen KU Leuven
- Study coordinator: Filip Verhaegen
- Email: filip.verhaegen@uzleuven.be
- Phone: +32 16 33 88 27
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.