Clinical trial Recruiting at 1 site Observational Ages 18 and up

Evaluating long-term outcomes of stereotactic radiotherapy for ventricular tachycardia

Official title: Cardiac RadiothErapy for VEntricular Tachycardia II - a Prospective Observational Cohort Study

Run by Universitaire Ziekenhuizen KU Leuven · NCT06744530 · Data updated 2026-11-12

This study is testing if a special type of radiation treatment can help people with hard-to-treat ventricular tachycardia feel better and stay safe over the long term.

More Ventricular Tachycardia (VT) trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment50 (estimated)
SponsorUniversitaire Ziekenhuizen KU Leuven
Academic / other
Locations1 site (Leuven)
StatusRecruiting
StartedJanuary 1, 2025
Main results expectedDecember 2033
Study endsDecember 2034
Registry record updatedApril 29, 2026
Trial IDNCT06744530 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients with therapy-refractory ventricular tachycardia who are eligible for stereotactic radiotherapy based on a multidisciplinary evaluation.

Probably not a fit

Patients who may not benefit from this study include those with contraindications for STAR, such as pregnancy, previous cardiac radiotherapy, or a life expectancy of less than six months without VT.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the long-term efficacy and safety of stereotactic radiotherapy ablation (STAR) in patients suffering from therapy-refractory ventricular tachycardia (VT). By focusing on patients who are eligible for STAR based on a multidisciplinary discussion, the study seeks to fill the gap in knowledge regarding the long-term outcomes of this treatment approach. Participants will be monitored for their responses and any adverse effects following the intervention, contributing valuable data to the field of cardiac care.

Why it matters

Potential benefit: If successful, this study could provide critical insights into the long-term effectiveness and safety of STAR for patients with refractory ventricular tachycardia.

How similar studies have gone: While stereotactic radiotherapy has become a standard care option, this study aims to provide new insights into its long-term outcomes, indicating a novel approach in this specific context.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Eligible for STAR for therapy-refractory VT based on a multidisciplinary discussion
* Ability to give a written informed consent and willingness to return for follow-up

Exclusion Criteria:

* Contra-indications for STAR, including pregnancy or breastfeeding, previous radiotherapy with cardiac involvement, life-expectancy \< 6 months in the absence of VT
* Any condition that is deemed a contraindication in the judgment of the investigators

Where it's running

  • UZ Leuven
    Leuven, Belgium
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.