Investigating brain activity and consciousness in patients with severe brain injuries

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The CONSCIUS study is an interventional study focusing on patients with acute brain injuries who have impaired consciousness. It involves the implantation of intracranial electrodes to monitor and analyze neural dynamics and seizures in these patients. The goal is to develop objective measures that can predict recovery of consciousness and improve treatment decisions in intensive care settings. By utilizing continuous EEG monitoring with high spatial and temporal resolution, the study aims to enhance our understanding of the thalamocortical mechanisms underlying consciousness.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 18 years old or older
* Brain injury of any kind, with impaired consciousness or suspected seizures

Exclusion Criteria:

* \< 18 years old
* Known pregnancy
* Any condition that, in the judgement of the investigator, makes participation in the study unsafe or unfeasible (e.g., irreversible coagulopathy, large intracranial tumors, surgical technical problems…)

Where it's running

• UZLeuven
  Leuven, Vlaams-Brabant, Belgium Recruiting

Study contacts

• Principal investigator: Tom Theys, MD PhD — Universitaire Ziekenhuizen KU Leuven
• Study coordinator: Steven Smeijers, MD
• Email: steven.smeijers@uzleuven.be
• Phone: +32 16 34 48 00

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.