Investigating the effects of endoscopic skull base surgery on smell

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study examines how endoscopic endonasal skull base surgery affects the sense of smell in patients. It combines clinical assessments with histomolecular analysis to understand the incidence and causes of olfactory dysfunction after surgery. The research team will evaluate patients before and after the procedure, collecting tissue samples to analyze the underlying mechanisms of any smell-related issues. The goal is to clarify the impact of this surgical approach on both olfactory and trigeminal functions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult patients scheduled for endoscopic endonasal skull base surgery

Exclusion Criteria:

* Pre-existing anosmia
* Patients has a history of previous endoscopic endonasal skull base surgery

Where it's running

• KU Leuven
  Leuven, Vlaams-Brabant, Belgium Recruiting
• Max Planck Research Unit for Neurogenetics
  Frankfurt am Main, Hesse, Germany Active not recruiting
• Leiden University Medical Center
  Leiden, South Holland, Netherlands Not yet recruiting

Study contacts

• Study coordinator: Julie van Waterschoot
• Email: julie.vanwaterschoot@kuleuven.be
• Phone: +32477910294

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.