Investigating the link between influenza and invasive pulmonary aspergillosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational trial aims to explore the immunological and pathological characteristics of patients with severe community-acquired pneumonia in the ICU, comparing those with influenza to those without. The study will include all consecutive patients aged 18 or older who are admitted to the ICU with respiratory distress and a microbiologically confirmed diagnosis of either influenza or non-influenza pneumonia. The findings will be correlated with the occurrence of secondary invasive pulmonary aspergillosis infections, providing insights into the impact of influenza on pneumonia outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* All patients older than 18 years, admitted to ICU with respiratory distress with microbiologically confirmed diagnosis of influenza (for inclusion in the influenza group)
* All patients older than 18 years, admitted to ICU for respiratory distress due to community- acquired pneumonia , with a microbiologically confirmed absence of influenza (for inclusion in the control group)

Exclusion Criteria:

* Age \< 18 years old
* Pregnant women
* No informed consent

Where it's running

• Universitaire Ziekenhuizen Leuven
  Leuven, Belgium Recruiting

Study contacts

• Principal investigator: Joost Wauters, PhD — UZ Leuven
• Study coordinator: Joost Wauters, PhD
• Email: joost.wauters@uzleuven.be
• Phone: 16344275

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.