Evaluating quality of life and functional outcomes in sarcoma patients after limb salvage surgery
Official title: Assessment of the Functional Outcome and Quality of Life in Sarcoma Patients
Run by Universitaire Ziekenhuizen KU Leuven · NCT05051059 · Data updated 2026-11-12
This study looks at how limb salvage surgery affects the quality of life and daily functioning of people aged 18 to 95 who have had surgery for bone or soft tissue sarcoma in their legs.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 95 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Universitaire Ziekenhuizen KU Leuven Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Leuven, Vlaams-Brabant) |
| Status | Recruiting |
| Started | October 1, 2021 |
| Main results expected | December 2026 |
| Study ends | December 2026 |
| Registry record updated | March 16, 2026 |
| Trial ID | NCT05051059 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients aged 18 to 95 who have undergone limb salvage surgery for lower extremity sarcoma at UZ Leuven and are at least one year post-surgery.
✕Probably not a fit
Patients with prior major lower limb surgeries or those with conditions affecting the locomotor system may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study assesses the functional outcomes and health-related quality of life in patients who have undergone limb salvage surgery for bone or soft tissue sarcoma in the lower extremities. It focuses on individuals aged 18 to 95 years who are at least one year post-surgery, evaluating their experiences and outcomes related to different surgical procedures. The research aims to provide insights into the psychological and physical impacts of these surgeries, helping to inform future treatment decisions for patients and their families.
Why it matters
Potential benefit: If successful, this study could enhance understanding of the best surgical options for improving quality of life in sarcoma patients.
How similar studies have gone: Previous studies have shown varying outcomes for different surgical approaches in sarcoma patients, indicating that this area of research is both relevant and necessary.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients who underwent limb salvage surgery for bone or soft tissue sarcoma of the lower extremity at UZ Leuven * 18 to 95 years old * Patients should be at least one year post surgery * Informed consent has obtained Exclusion Criteria: * Patients who received major prior surgery of the lower limbs or with any pathology, injury or disorder known to affect the locomotor system * Skeletally immature individuals * No informed consent has obtained
Where it's running
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UZ Leuven
Leuven, Vlaams-Brabant, Belgium Recruiting
Study contacts
- Principal investigator: Hazem Wafa — Universitaire Ziekenhuizen KU Leuven
- Study coordinator: Hazem Wafa
- Email: hazem.wafa@uzleuven.be
- Phone: +32 16 33 88 73
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Preoperative Immunonutrition for bone and soft tissue sarcoma patients
This study tests whether a short course of an oral nutrition supplement before surgery can help patients with bone or soft tissue sarcomas recover better after major tumor-related surgery.
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Using a special dye to guide surgery for sarcoma removal
This study is testing whether a special dye can help surgeons remove sarcomas more accurately by showing them where the cancer ends during surgery.
-
Assessing early psychiatric referral effects on mental health in sarcoma patients
This study tests whether getting early mental health support helps sarcoma patients feel less anxious and depressed while recovering from surgery.
-
Quality assessment of sarcoma care in Europe and Latin America
This study looks at how well patients with different types of sarcoma are treated in Europe and Latin America to see if care is better at expert centers and to find ways to improve outcomes.
-
New method to deliver chemotherapy directly into the lungs for sarcoma patients
This study is testing a new way to deliver chemotherapy directly into the lungs during surgery for sarcoma patients to see if it can better target hidden cancer cells and improve their outcomes.
-
68Ga-HX01 PET/CT Imaging in Soft Tissue Sarcoma patients
This study tests whether a 68Ga-HX01 injection can help PET/CT imaging better characterize soft tissue sarcoma in adults who have exhausted standard treatments or have no good options.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.