Condition

Subarachnoid Hemorrhage clinical trials and research

• 21Clinical trials
• 37NIH research projects
• 2New in 30 days
• 12Countries

Newest Subarachnoid Hemorrhage clinical trials

All recruiting trials (21)

• Smartphone-based EEG to detect hidden awareness in ICU patients with brain injuries

  Researchers will test a smartphone-enabled EEG to see if it can reveal Cognitive Motor Dissociation in ICU patients who can’t show commands at bedside.

  Recruiting Columbia University · Miami, Florida and 8 other locations · NCT07917728

• French validation of the SAHOT outcome tool after subarachnoid hemorrhage

  This study tests whether a French version of the SAHOT questionnaire reliably measures outcomes in adults after subarachnoid hemorrhage.

  Recruiting Fondation Ophtalmologique Adolphe de Rothschild · Paris · NCT07894666

• Prognostic model for neurocritical patients using multimodal brain monitoring

  This study tests a model that uses EEG, TCD, and NIRS data to predict 90-day outcomes (awake, coma, or death) in adults with acute brain injuries in intensive care.

  Recruiting Xiangya Hospital of Central South University · Changsha, Hunan · NCT07115459

• Investigating the effects of stellate ganglion block on retinal blood flow

  This study is testing if a special nerve block used for pain relief can improve blood flow in the eyes of patients with severe brain injuries.

  Recruiting University of Texas Southwestern Medical Center · Dallas, Texas · NCT06797752

• Evaluating outcomes in neurosurgery using standardized measures

  This study is trying to see how different factors affect the results of brain surgeries by collecting information from patients before and after their operations.

  Recruiting at 11 sites Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta · Bergamo, BG and 26 other locations · NCT06724029

• Assessing ventilatory parameters in patients with acute neurological injuries

  This study is trying to see how different breathing machine settings affect the brain health of adults with serious neurological injuries like strokes or brain trauma.

  Recruiting Ramos Mejía Hospital · Ciudad Autonoma de Buenos Aires, Buenos Aires · NCT06192342

• Using advanced MRI to study brain metabolism in traumatic brain injury

  This study is testing a new type of MRI to see how brain metabolism changes in people with traumatic brain injury compared to healthy individuals and those with a different brain condition.

  Recruiting Phase 1 University of Maryland, Baltimore · Baltimore, Maryland · NCT06103201

• Examining blood pressure treatment in ICU patients with brain hemorrhage

  This study tests how changing blood pressure affects blood flow in the brains of ICU patients who have had a brain hemorrhage.

  Recruiting Umeå University · Umeå · NCT06033378

• Registry of brain-heart comorbidity in China

  This study is trying to build a big database to better understand and manage the connection between brain and heart problems in people across China.

  Recruiting Beijing Tiantan Hospital · Beijing, Beijing Municipality and 13 other locations · NCT05961748

• Evaluating brain blood flow using contrast-enhanced ultrasound

  This study is testing a new ultrasound method to see if it can help doctors check blood flow in the brains of patients with recent brain injuries.

  Recruiting Assistance Publique - Hôpitaux de Paris · Paris · NCT05893407

• Evaluating a new method for draining fluid and blood in brain hemorrhages

  This study is testing a new device for draining fluid and blood from the brain to see if it works better than the standard method for patients with brain hemorrhages.

  Recruiting Ohio State University · Columbus, Ohio · NCT05649904

• A registry to improve the lives of stroke survivors in South London

  This study is tracking stroke survivors in South London to see how their health and quality of life change over time.

  Recruiting at 4 sites Guy's and St Thomas' NHS Foundation Trust · London and 6 other locations · NCT05298436

• Using antibiotics with external ventricular drains to prevent infections

  This study tests whether giving antibiotics for 24 hours or for the whole time a patient has an external ventricular drain can help prevent infections in people with brain bleeding.

  Recruiting Phase 1 Montefiore Medical Center · The Bronx, New York · NCT05001750

• Understanding cognitive changes after stroke

  This study is trying to find out what affects thinking and memory changes in people who have had a stroke, to help improve recovery in the future.

  Recruiting at 28 sites Massachusetts General Hospital · Phoenix, Arizona and 30 other locations · NCT04916210

• Monitoring intracranial pressure to assess patient outcomes

  This study is testing if continuous monitoring of pressure inside the skull can help doctors understand how well patients with serious brain injuries are doing and predict their recovery.

  Recruiting University of Milano Bicocca · Monza, MB · NCT04459806

• Understanding recovery after brain hemorrhage

  This study looks at how different types of brain bleeding affect recovery and how treatments in the hospital can impact patient outcomes for people with serious brain injuries.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT04189471

• Impact of fluid type on outcomes in patients with subarachnoid hemorrhage

  This study tests whether using different types of IV fluids can improve recovery for patients who have had a subarachnoid hemorrhage.

  Recruiting at 3 sites Insel Gruppe AG, University Hospital Bern · Sankt Gallen, Canton of St. Gallen and 2 other locations · NCT04043598

• Registry connecting stroke survivors with research opportunities

  This study connects stroke survivors with research opportunities to help find new treatments that can improve their recovery.

  Recruiting University of California, San Francisco · San Francisco, California · NCT03318432

• Registry for managing aneurysmal subarachnoid hemorrhage in Switzerland

  This study is collecting information from patients in Switzerland who have had an aneurysmal subarachnoid hemorrhage to see how well they are treated and how they recover.

  Recruiting at 9 sites University Hospital, Geneva · Aarau, Canton of Aargau and 8 other locations · NCT03245866

• Using electrical stimulation and high protein diet to aid recovery after brain hemorrhage

  This study is testing if using electrical stimulation and a high protein diet can help adults recover better after a brain hemorrhage compared to standard care.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT03201094

• Comparing lumbar and extraventricular drains to prevent complications after brain hemorrhage

  This study is testing whether using a lumbar drain or an extraventricular drain helps prevent complications in patients who have had a brain hemorrhage.

  Recruiting University of California, San Diego · San Diego, California · NCT03065231

NIH-funded research (37)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Cognitive screening after an aneurysmal brain bleed

  Using patient questionnaires to find thinking and memory problems in people recovering from aneurysmal subarachnoid hemorrhage.

  NIH research University of Texas Hlth Sci Ctr Houston · Houston, United States · NIH-11468520

• Blood test to predict delayed brain injury after an aneurysm bleed

  This project is creating a blood test to spot which people who had a brain aneurysm bleed are likely to develop delayed brain injury in the days after the bleed.

  NIH research University of Texas Hlth Sci Ctr Houston · Houston, United States · NIH-11467911

• 3D brain blood vessel model to study subarachnoid hemorrhage and test therapies

  A researcher will develop a 3D printed, biomimetic brain model to study subarachnoid hemorrhage and screen potential nanoparticle-based treatments.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11400496

• Biomarkers to Fine-Tune Intrathecal Nicardipine for Brain Bleeding-Related Stroke

  Researchers are testing biomarkers to personalize intrathecal nicardipine treatment for patients after subarachnoid hemorrhage to prevent brain damage.

  NIH research Emory University · Atlanta, United States · NIH-11385464

• Adropin as a shield for the brain after a brain hemorrhage

  A potential treatment with adropin is being studied to protect brain cells after a subarachnoid hemorrhage and reduce stroke-like damage.

  NIH research University of Florida · Gainesville, United States · NIH-11380727

• Manganese-based compound as a potential therapy for subarachnoid hemorrhage

  A new manganese porphyrin-based drug is being explored as a possible treatment to reduce brain injury after a subarachnoid hemorrhage.

  NIH research Barrow Neurological Institute at St. Joseph's Hospital and Medical Center · Phoenix, United States · NIH-11373497

• START Network for Promising Novel Drug Testing in Subarachnoid Hemorrhage

  A network of three sites will test two potential treatments in a late-stage, animal model study of subarachnoid hemorrhage to help improve outcomes for patients who suffer this brain injury.

  NIH research University of Florida · Gainesville, United States · NIH-11367161

• NAMPT and NAD+ help protect the brain after subarachnoid hemorrhage

  Aims to find how NAMPT and NAD+ help shield the brain from injury after a type of stroke called aneurysmal subarachnoid hemorrhage.

  NIH research Washington University · Saint Louis, United States · NIH-11364200

• Ischemia-protective effects of anesthetic conditioning after brain bleed

  This grant studies how certain anesthetics might protect the brain after an aneurysmal brain bleed to improve recovery prospects.

  NIH research Washington University · Saint Louis, United States · NIH-11364112

• Brain stimulation to help thinking after aneurysm-related brain bleeding

  This project looks at whether targeted brain stimulation can help people regain thinking and memory after bleeding around the brain from a burst aneurysm.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11303354

• Using deferiprone to enhance cognitive recovery after subarachnoid hemorrhage

  This study is looking at how a medication called deferiprone, which helps lower iron levels in the brain, might improve memory and thinking skills in people who have recovered from a brain bleed called aneurysmal subarachnoid hemorrhage.

  NIH research Duke University · Durham, United States · NIH-11303175

• Molecularly mapping early brain injury after brain bleed using human brain organoids and patient CSF

  Scientists are studying how early brain injury after aneurysmal subarachnoid hemorrhage happens in people, by using patient CSF and human brain organoids to find what signals cause damage and why women may have worse outcomes.

  NIH research Barrow Neurological Institute at St. Joseph's Hospital and Medical Center · Phoenix, United States · NIH-11290705

• Noninvasive bedside monitoring of brain blood flow after brain bleed (aSAH)

  Aims to use a small, noninvasive device to monitor brain blood flow in patients with aneurysmal subarachnoid hemorrhage to help predict complications and guide treatment.

  NIH research University of South Florida · Tampa, United States · NIH-11237140

• PEDF protein to protect the brain after aneurysmal subarachnoid hemorrhage

  This work looks at whether a natural protein called PEDF can protect the brain and its blood vessels after bleeding from a brain aneurysm.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-11232362

• Improving sleep management for adults recovering from brain hemorrhage

  This study is designed to help adults who have had a subarachnoid hemorrhage improve their sleep with a special program created just for them, using input from both survivors and their caregivers to make it as helpful as possible.

  NIH research University of Washington · Seattle, United States · NIH-11192959

• 3D lab-grown model of brain blood vessels to test treatments for subarachnoid hemorrhage

  This project builds a 3D lab model of brain blood vessels to try new therapies that could help people who have subarachnoid hemorrhage (brain bleeding).

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11190419

• Biomarkers to guide spinal nicardipine for blood-vessel spasm after bleeding around the brain

  Doctors are using a bedside optical monitor to see if it helps pick which patients with bleeding around the brain should get spinal (intrathecal) nicardipine to treat blood-vessel spasm.

  NIH research Emory University · Atlanta, United States · NIH-11174552

• Adropin to protect the brain after a subarachnoid hemorrhage

  See whether a natural peptide called adropin can protect the brain and blood vessels in people who have had a subarachnoid hemorrhage.

  NIH research University of Florida · Gainesville, United States · NIH-11144279

• Finding blood markers to predict brain complications after a stroke.

  This study is looking at blood samples from patients who have had a brain bleed to find markers that can help predict if they might develop a serious complication later on, so doctors can provide better care and help patients avoid longer hospital stays.

  NIH research University of Texas Hlth Sci Ctr Houston · Houston, United States · NIH-11134767

• Protecting the Brain After Aneurysmal Subarachnoid Hemorrhage

  This project explores how a special type of 'conditioning' can protect the brain from damage after a severe type of stroke called aneurysmal subarachnoid hemorrhage.

  NIH research Washington University · Saint Louis, United States · NIH-11117006

• Using brain stimulation to help improve thinking skills after a brain hemorrhage.

  This study is looking at how brain stimulation might help people who have had a subarachnoid hemorrhage improve their thinking skills and overall brain function, with the goal of making life better for those recovering from this type of brain injury.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11075854

• Identifying blood markers for brain complications after a type of stroke.

  This study is looking at how certain blood markers can help doctors figure out which patients who have had a brain bleed might face complications later on, so they can get the right care sooner and improve their recovery.

  NIH research University of California at Davis · Davis, United States · NIH-11030271

• Investigating how venous issues affect brain health after a type of stroke.

  This study is looking at how problems with blood flow in the veins can affect people who have had a serious type of stroke called aneurysmal subarachnoid hemorrhage, and it hopes to find new ways to help them recover better.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-11012883

• Monitoring blood flow in the brain after a stroke caused by an aneurysm.

  This study is looking at ways to help people who have had a specific type of stroke called aSAH by using a new tool to keep an eye on blood flow in the brain, so doctors can quickly spot any problems and take action to help prevent serious complications.

  NIH research University of South Florida · Tampa, United States · NIH-11000302

• Using CBD to improve outcomes after brain bleeding from aneurysms

  This study is looking at how cannabidiol (CBD) might help people who have had a subarachnoid hemorrhage, which is a serious brain condition, by potentially improving blood flow and reducing brain damage to help them recover better.

  NIH research University of Kentucky · Lexington, United States · NIH-10994636

• Understanding metabolic changes after brain hemorrhage

  This study is looking at how a serious brain condition called aneurysmal subarachnoid hemorrhage affects the body's metabolism and inflammation, with the goal of finding ways to predict how well patients will recover by analyzing blood samples.

  NIH research University of Texas Hlth Sci Ctr Houston · Houston, United States · NIH-10991333

• Understanding how a protein protects the brain after a specific type of stroke.

  This study is looking at how a protein called PEDF might help protect the brain after a serious type of stroke called aneurysmal subarachnoid hemorrhage, with the hope that it could lead to better treatments for people who have experienced this condition.

  NIH research Loma Linda University · Loma Linda, UNITED STATES · NIH-10989904

• Using Satralizumab to treat complications from brain aneurysms.

  This study is looking at how well the drug Satralizumab can help people recover after a brain aneurysm by reducing complications like vasospasm, and it’s designed for patients who have had this type of hemorrhage.

  NIH research University of Florida · Gainesville, United States · NIH-10952347

• Creating a 3D model to study brain hemorrhages and test new treatments

  This study is creating a 3D model of the brain's blood vessels to help us understand subarachnoid hemorrhage (SAH) better and find new treatments, so patients with this type of stroke can have more effective options for recovery.

  NIH research Vanderbilt University · Nashville, UNITED STATES · NIH-10908621

• Finding better ways to treat brain blood vessel constriction after a stroke.

  This study is looking at how a medication called nicardipine can help people who have had a type of stroke called a subarachnoid hemorrhage by improving blood flow in the brain and reducing the risk of serious complications, and they're also trying to find ways to predict who will benefit the most from this treatment.

  NIH research Emory University · Atlanta, United States · NIH-10908464

• Protecting the brain from injury after bleeding in the brain

  This study is looking at how a hormone called adropin might help protect the brain after a type of bleeding called subarachnoid hemorrhage, with the goal of finding new ways to reduce brain damage and help patients recover better.

  NIH research University of Florida · Gainesville, United States · NIH-10884468

• Investigating how hypoxic conditioning can protect the brain after a subarachnoid hemorrhage.

  This study is looking at how controlled low-oxygen conditions might help protect the brain after a serious bleeding event called a subarachnoid hemorrhage, with the goal of finding new ways to improve recovery for patients.

  NIH research Washington University · Saint Louis, United States · NIH-10881913

• Using Deferiprone to Enhance Cognitive Recovery After Subarachnoid Hemorrhage

  This study is looking at how a medication called deferiprone, which helps lower iron levels in the brain, might improve memory and thinking skills in people who have recovered from a brain bleed caused by an aneurysm.

  NIH research Duke University · Durham, United States · NIH-10879066

• Using non-invasive vagus nerve stimulation to reduce inflammation after brain hemorrhages

  This study is looking at a gentle way to stimulate the vagus nerve to help reduce inflammation in people who have had a brain bleed from a ruptured aneurysm, and it aims to see if this method can improve their recovery without using medications.

  NIH research Washington University · Saint Louis, United States · NIH-10870057

• Investigating how isoflurane may protect the brain after a hemorrhagic stroke.

  This study is looking at how a common anesthetic called isoflurane might help protect the brain after a serious condition called aneurysmal subarachnoid hemorrhage, and it's using animal models to find out how it works so that new treatments can be developed for people with brain injuries.

  NIH research Washington University · Saint Louis, United States · NIH-10849790

• Identifying brain injury risks in patients with aneurysmal subarachnoid hemorrhage using brain activity monitoring.

  This study is looking at how to better manage blood pressure for people who have had a brain bleed from an aneurysm, by closely monitoring their brain activity to find the best targets for blood flow, which could help prevent further complications and improve recovery.

  NIH research Yale University · New Haven, United States · NIH-10821463

• Improving cognitive assessment after brain hemorrhages for better patient outcomes

  This study is looking to improve how we spot and understand thinking problems in people who have had a brain bleed, especially focusing on African American and rural patients who might not get the help they need, so we can help them live better lives.

  NIH research University of Tennessee Health Sci Ctr · Memphis, United States · NIH-10789774

Related topics

Quick answers

How many Subarachnoid Hemorrhage clinical trials are recruiting right now?

21, as of November 12, 2026. 2 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 12 countries. The most sites are in United States (10 trials), China (2 trials), Italy (2 trials), France (2 trials), Switzerland (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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