Brain stimulation to help thinking after aneurysm-related brain bleeding
Brain Stimulation to Improve Neurocognitive Deficits After Subarachnoid Hemorrhage
['FUNDING_R01'] · MASSACHUSETTS GENERAL HOSPITAL · NIH-11303354
This project looks at whether targeted brain stimulation can help people regain thinking and memory after bleeding around the brain from a burst aneurysm.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MASSACHUSETTS GENERAL HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-11303354 on ClinicalTrials.gov |
What this research studies
After a ruptured brain aneurysm many survivors still struggle with thinking, memory, and returning to work. Researchers will study how brain networks that support thinking change after this kind of bleeding using imaging and behavioral tests. They will use animal models and brain stimulation approaches to try to restore normal network activity and improve behavior, with the goal of translating successful methods toward people. If the method works in the lab, it could lead to clinical trials testing noninvasive stimulation in survivors of subarachnoid hemorrhage.
Who could benefit from this research
Good fit: Ideal candidates for future trials would be survivors of aneurysmal subarachnoid hemorrhage who have ongoing cognitive problems such as memory or attention difficulties.
Not a fit: People whose cognitive decline is from progressive neurodegenerative disease or from causes unrelated to aneurysmal subarachnoid hemorrhage are unlikely to benefit from this specific approach.
Why it matters
Potential benefit: If successful, this work could lead to treatments that improve memory, thinking, and daily functioning for people recovering from aneurysmal brain bleeding.
How similar studies have performed: Noninvasive brain stimulation has shown mixed but sometimes promising benefits in other types of stroke and brain injury, but applying it specifically after subarachnoid hemorrhage is a newer and less-tested approach.
Where this research is happening
BOSTON, UNITED STATES
- MASSACHUSETTS GENERAL HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CHUNG, DAVID YOUNG — MASSACHUSETTS GENERAL HOSPITAL
- Study coordinator: CHUNG, DAVID YOUNG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired brain injury