Using CBD to improve outcomes after brain bleeding from aneurysms

Cannabidiol (CBD) as a Potential Therapeutic for Experimental Subarachnoid Hemorrhage

['FUNDING_R21'] · UNIVERSITY OF KENTUCKY · NIH-10994636

This study is looking at how cannabidiol (CBD) might help people who have had a subarachnoid hemorrhage, which is a serious brain condition, by potentially improving blood flow and reducing brain damage to help them recover better.

Quick facts

Phase['FUNDING_R21']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF KENTUCKY (nih funded)
Locations1 site (LEXINGTON, UNITED STATES)
Trial IDNIH-10994636 on ClinicalTrials.gov

What this research studies

This research investigates the potential of cannabidiol (CBD) as a treatment for subarachnoid hemorrhage (SAH), a serious condition often caused by a ruptured aneurysm. The study aims to understand how CBD may help stabilize blood vessels in the brain, improve blood flow, and reduce brain injury following SAH. By conducting preclinical experiments, the researchers will explore the anti-inflammatory and neuroprotective properties of CBD and how it may enhance recovery for patients affected by this condition. The ultimate goal is to identify new therapeutic strategies that could significantly improve patient outcomes after SAH.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults over 21 years old who have experienced a subarachnoid hemorrhage.

Not a fit: Patients who have not experienced a subarachnoid hemorrhage or those with other unrelated conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to a novel treatment that improves recovery and reduces disability and mortality for patients suffering from subarachnoid hemorrhage.

How similar studies have performed: While CBD has shown promise in other injury models, this specific application for subarachnoid hemorrhage is novel and has not been previously tested.

Where this research is happening

LEXINGTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired brain injury

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.