Understanding recovery after brain hemorrhage

Recovery After Cerebral Hemorrhage--Improving Outcomes for Patients With Life-Threatening Neurologic Illness

Observational University of Maryland, Baltimore · NCT04189471

This study looks at how different types of brain bleeding affect recovery and how treatments in the hospital can impact patient outcomes for people with serious brain injuries.

Quick facts

Study typeObservational
Enrollment5000 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Maryland, Baltimore Academic / other
Locations1 site (Baltimore, Maryland)
Trial IDNCT04189471 on ClinicalTrials.gov

What this trial studies

This observational study aims to investigate the common pathophysiological pathways associated with life-threatening neurological illnesses, particularly focusing on various types of brain hemorrhages. By utilizing advanced monitoring tools such as CT, MRI, and ultrasound, the study seeks to understand how systemic complications and standard care practices may worsen brain injury. It will collect data from patients admitted to the NeuroCritical Care Unit at the University of Maryland, both retrospectively and prospectively, to analyze the impact of interventions on patient outcomes.

Who should consider this trial

Good fit: Ideal candidates include individuals diagnosed with life-threatening neurological illnesses who have been admitted to the Neuro ICU within 14 days of their initial injury.

Not a fit: Patients with known pre-existing neurological deficits, severe prior strokes, severe dementia, severe head injuries, or those who are prisoners may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved understanding and management of brain injuries, potentially enhancing recovery outcomes for patients.

How similar studies have performed: While this approach is observational and builds on existing knowledge, similar studies have shown promise in understanding brain injuries and their management.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* clinical diagnosis of potentially life-threatening neurological illness
* admitted to Neuro ICU within 14 days of initial injury

Exclusion Criteria:

* known pre-existing neurological deficits related to a developmental disorder
* prior severe stroke
* prior severe dementia
* prior severe head injury
* prisoners

Where this trial is running

Baltimore, Maryland

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Intracerebral HemorrhageSubarachnoid HemorrhageIntraventricular HemorrhageNontraumatic HaemorrhageStatus Epilepticushemorrhageintracerebral hemorrhageSAH
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.