Clinical trial Recruiting at 1 site Observational Ages 18 and up

Understanding recovery after brain hemorrhage

Official title: Recovery After Cerebral Hemorrhage--Improving Outcomes for Patients With Life-Threatening Neurologic Illness

Run by University of Maryland, Baltimore · NCT04189471 · Data updated 2026-11-12

This study looks at how different types of brain bleeding affect recovery and how treatments in the hospital can impact patient outcomes for people with serious brain injuries.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment5000 (estimated)
SponsorUniversity of Maryland, Baltimore
Academic / other
Locations1 site (Baltimore, Maryland)
StatusRecruiting
StartedSeptember 8, 2014
Main results expectedJanuary 1, 2034
Study endsJanuary 1, 2034
Registry record updatedJuly 2, 2026
Trial IDNCT04189471 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include individuals diagnosed with life-threatening neurological illnesses who have been admitted to the Neuro ICU within 14 days of their initial injury.

Probably not a fit

Patients with known pre-existing neurological deficits, severe prior strokes, severe dementia, severe head injuries, or those who are prisoners may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the common pathophysiological pathways associated with life-threatening neurological illnesses, particularly focusing on various types of brain hemorrhages. By utilizing advanced monitoring tools such as CT, MRI, and ultrasound, the study seeks to understand how systemic complications and standard care practices may worsen brain injury. It will collect data from patients admitted to the NeuroCritical Care Unit at the University of Maryland, both retrospectively and prospectively, to analyze the impact of interventions on patient outcomes.

Why it matters

Potential benefit: If successful, this study could lead to improved understanding and management of brain injuries, potentially enhancing recovery outcomes for patients.

How similar studies have gone: While this approach is observational and builds on existing knowledge, similar studies have shown promise in understanding brain injuries and their management.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* clinical diagnosis of potentially life-threatening neurological illness
* admitted to Neuro ICU within 14 days of initial injury

Exclusion Criteria:

* known pre-existing neurological deficits related to a developmental disorder
* prior severe stroke
* prior severe dementia
* prior severe head injury
* prisoners

Where it's running

  • University of Maryland Medical Center
    Baltimore, Maryland, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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  • Care bundle to improve recovery after intracerebral haemorrhage

    This trial will try a structured treatment package—rapid reversal of blood thinners when needed, early intensive blood pressure lowering, and treatment of fever and high blood sugar—to see if it improves 3‑month outcomes for adults with spontaneous intracerebral haemorrhage who arrive within 24 hours of symptom onset.

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  • Evaluating a new method for draining fluid and blood in brain hemorrhages

    This study is testing a new device for draining fluid and blood from the brain to see if it works better than the standard method for patients with brain hemorrhages.

    Recruiting Ohio State University · Columbus, Ohio · NCT05649904

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.