Understanding recovery after brain hemorrhage
Official title: Recovery After Cerebral Hemorrhage--Improving Outcomes for Patients With Life-Threatening Neurologic Illness
Run by University of Maryland, Baltimore · NCT04189471 · Data updated 2026-11-12
This study looks at how different types of brain bleeding affect recovery and how treatments in the hospital can impact patient outcomes for people with serious brain injuries.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 5000 (estimated) |
| Sponsor | University of Maryland, Baltimore Academic / other |
| Locations | 1 site (Baltimore, Maryland) |
| Status | Recruiting |
| Started | September 8, 2014 |
| Main results expected | January 1, 2034 |
| Study ends | January 1, 2034 |
| Registry record updated | July 2, 2026 |
| Trial ID | NCT04189471 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals diagnosed with life-threatening neurological illnesses who have been admitted to the Neuro ICU within 14 days of their initial injury.
✕Probably not a fit
Patients with known pre-existing neurological deficits, severe prior strokes, severe dementia, severe head injuries, or those who are prisoners may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to investigate the common pathophysiological pathways associated with life-threatening neurological illnesses, particularly focusing on various types of brain hemorrhages. By utilizing advanced monitoring tools such as CT, MRI, and ultrasound, the study seeks to understand how systemic complications and standard care practices may worsen brain injury. It will collect data from patients admitted to the NeuroCritical Care Unit at the University of Maryland, both retrospectively and prospectively, to analyze the impact of interventions on patient outcomes.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and management of brain injuries, potentially enhancing recovery outcomes for patients.
How similar studies have gone: While this approach is observational and builds on existing knowledge, similar studies have shown promise in understanding brain injuries and their management.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * clinical diagnosis of potentially life-threatening neurological illness * admitted to Neuro ICU within 14 days of initial injury Exclusion Criteria: * known pre-existing neurological deficits related to a developmental disorder * prior severe stroke * prior severe dementia * prior severe head injury * prisoners
Where it's running
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University of Maryland Medical Center
Baltimore, Maryland, United States Recruiting
Study contacts
- Principal investigator: Gunjan Y Parikh, MD — University of Maryland, Baltimore
- Study coordinator: Gunjan Parikh
- Email: gparikh@som.umaryland.edu
- Phone: 4103284515
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Smartphone-based EEG to detect hidden awareness in ICU patients with brain injuries
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Investigating the effects of stellate ganglion block on retinal blood flow
This study is testing if a special nerve block used for pain relief can improve blood flow in the eyes of patients with severe brain injuries.
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Care bundle to improve recovery after intracerebral haemorrhage
This trial will try a structured treatment package—rapid reversal of blood thinners when needed, early intensive blood pressure lowering, and treatment of fever and high blood sugar—to see if it improves 3‑month outcomes for adults with spontaneous intracerebral haemorrhage who arrive within 24 hours of symptom onset.
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Registry of brain-heart comorbidity in China
This study is trying to build a big database to better understand and manage the connection between brain and heart problems in people across China.
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Evaluating a new method for draining fluid and blood in brain hemorrhages
This study is testing a new device for draining fluid and blood from the brain to see if it works better than the standard method for patients with brain hemorrhages.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.