Finding blood markers to predict brain complications after a stroke.
Official title: Discovery of Plasma Biomarkers of Delayed Cerebral Ischemia after Subarachnoid Hemorrhage
Funded at University of Texas Hlth Sci Ctr Houston · NIH-11134767 · Data updated 2026-11-12
This study is looking at blood samples from patients who have had a brain bleed to find markers that can help predict if they might develop a serious complication later on, so doctors can provide better care and help patients avoid longer hospital stays.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Sci Ctr Houston NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | March 15, 2022 |
| Project end | February 28, 2027 |
| Funding year | 2025 |
| Award (this year) | $519,850 |
| NIH project number | 4R33NS119640-04 |
| Project ID | NIH-11134767 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients who have recently experienced a subarachnoid hemorrhage and are being monitored for potential complications.
✕Less likely to help
Patients who have not experienced a subarachnoid hemorrhage or those who are not at risk for delayed cerebral ischemia may not benefit from this research.
What this research studies
This research focuses on identifying plasma biomarkers that can predict the occurrence of delayed cerebral ischemia (DCI) in patients who have experienced a subarachnoid hemorrhage (SAH). By analyzing blood samples from SAH patients, the study aims to discover specific biological markers that indicate which patients are at risk of developing DCI, a serious complication that can occur days after the initial hemorrhage. The goal is to improve patient management by enabling targeted interventions and reducing unnecessary prolonged hospital stays. This could lead to better resource allocation and improved outcomes for patients at risk of DCI.
Why it matters
Potential benefit: If successful, this research could lead to earlier identification and treatment of patients at risk for serious complications after a stroke, potentially improving recovery outcomes.
How similar studies have gone: While there have been attempts to identify biomarkers for DCI, this research is exploring novel approaches that have not yet been fully validated in clinical settings.
Where this research is happening
-
University of Texas Hlth Sci Ctr Houston
Houston, United States Active
Researchers
- Principal investigator: Choi, Huimahn Alex — University of Texas Hlth Sci Ctr Houston
- Study coordinator: Choi, Huimahn Alex
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A new manganese porphyrin-based drug is being explored as a possible treatment to reduce brain injury after a subarachnoid hemorrhage.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.