ischemic stroke Clinical Trials and Research
Also known as: brain ischemia, cerebral infarction, ischemic cerebrovascular accident (cva), clot stroke, occlusive stroke, embolic stroke, thrombotic stroke · ICD-10: I63
An ischemic stroke occurs when a blood clot blocks blood flow to part of the brain, leading to brain damage. Clinical trial research is actively exploring new ways to prevent, treat, and improve recovery from ischemic strokes. Find a Trial helps patients search for active studies.
Search ischemic stroke trials →
Common questions about ischemic stroke clinical trials
What are the different phases of clinical trials for ischemic stroke?
Clinical trials progress through phases (1, 2, 3, 4) to test safety, dosage, and effectiveness of new interventions. Early phases involve fewer participants, while later phases involve more, as detailed on ClinicalTrials.gov.
Do clinical trials for ischemic stroke cost money to join?
Often, study-related medical care and interventions are provided at no cost to participants. However, some trials might not cover all routine medical care or travel expenses, according to information on ClinicalTrials.gov.
What are current research directions in ischemic stroke clinical trials?
Current research focuses on improving acute treatments to restore blood flow, developing neuroprotective strategies to minimize brain damage, and enhancing rehabilitation techniques. Data from NIH RePORTER shows ongoing studies in these areas.
What types of interventions are studied in ischemic stroke trials?
Interventions include new clot-busting medications (thrombolytics), mechanical thrombectomy devices, neuroprotective drugs, and various rehabilitation therapies. These are investigated to improve patient outcomes, as found on ClinicalTrials.gov.
Are there specific biomarkers used in ischemic stroke research?
Researchers study biomarkers like specific blood proteins, imaging markers (e.g., infarct volume, penumbra size), and genetic factors to predict stroke risk, severity, and treatment response. This helps personalize care, according to NIH RePORTER.
What might prevent someone from joining an ischemic stroke trial?
Common exclusion criteria can include recent major surgery, other serious medical conditions, or a history of bleeding disorders. These are in place to protect participants and ensure study integrity, as outlined on ClinicalTrials.gov.
How do clinical trials address recovery and rehabilitation after an ischemic stroke?
Many trials investigate novel rehabilitation strategies, such as new physical, occupational, and speech therapies, or brain stimulation techniques. The goal is to improve long-term functional recovery and quality of life, as seen on ClinicalTrials.gov.
How to find a ischemic stroke trial that fits you
- Describe your ischemic stroke situation in detail — stage if applicable, prior treatments, age, and other relevant conditions.
- Use the location filter (worldwide, US, US & Canada, Europe) to narrow to trials near you.
- Review each trial's eligibility criteria carefully. Save 2–5 candidates with their NCT numbers.
- Discuss with your treating clinician before contacting the research site.
Browse all ischemic stroke trials →