Impact of fluid type on outcomes in patients with subarachnoid hemorrhage

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effects of different types of intravenous fluids on patients who have suffered a subarachnoid hemorrhage. It specifically compares sodium-rich normal saline to sodium-depleted lactated Ringer's solution to determine which fluid leads to better clinical outcomes. The primary focus is on the occurrence of vasospasm, a serious complication, as well as other factors such as mortality, brain edema, and overall patient recovery. The study aims to provide insights into how fluid choice can influence recovery in critically ill patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

All adult patients suffering from non-traumatic subarachnoid haemorrhage.

Exclusion Criteria:

* Patients with major intra-cranial trauma
* Diagnosis of an AV-malformation as the source of subarachnoid hemorrhage on the primary CT/MRI or angiography
* More than 24 hours after diagnosis of subarachnoid haemorrhage as diagnosed by cerebral imaging (CT scan or MRI)
* Patients with clear limitation to therapy at hospital admission (eg ICU admission for evaluation of organ donation)
* Declining of informed consent

Where it's running

• Department of perioperative Intensive Care Medicine
  Sankt Gallen, Canton of St. Gallen, Switzerland Recruiting
• Department of Intensive Care, Bern University Hospital and University of Bern, Bern, Switzerland
  Bern, Switzerland Recruiting
• Department of Intensive Care Medicine
  Geneva, Switzerland Recruiting

Study contacts

• Principal investigator: Anna S Messmer, MD — Department of Intensive Care, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland
• Study coordinator: Anna S Messmer, MD
• Email: anna.messmer@insel.ch
• Phone: +41316322111

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.