Protecting the brain from injury after bleeding in the brain
Neurovascular protection by adropin in acute neural injury from subarachnoid hemorrhage
This study is looking at how a hormone called adropin might help protect the brain after a type of bleeding called subarachnoid hemorrhage, with the goal of finding new ways to reduce brain damage and help patients recover better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project ID | NIH-10884468 on NIH RePORTER |
What this research studies
This research investigates how a hormone called adropin can help protect the brain from damage caused by subarachnoid hemorrhage, a type of bleeding in the brain. The study focuses on understanding the mechanisms behind brain injury following this event, particularly how adropin may improve blood flow and reduce oxidative stress. By examining the effects of adropin on brain cells and blood vessels, the researchers aim to find new therapeutic strategies to minimize brain damage and improve recovery outcomes for patients. The research involves both laboratory experiments and potential clinical applications.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients who have survived a subarachnoid hemorrhage and are at risk for subsequent brain injury.
Not a fit: Patients who have not experienced a subarachnoid hemorrhage or those with chronic brain injuries unrelated to this condition may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that significantly reduce brain injury and improve recovery for patients who experience subarachnoid hemorrhage.
How similar studies have performed: Previous research has shown promising results with similar approaches targeting neuroprotection in brain injuries, suggesting potential for success in this study.
Where this research is happening
Gainesville, United States
- University of Florida — Gainesville, United States (Active)
Researchers
- Principal investigator: Hoh, Brian Lim — University of Florida
- Study coordinator: Hoh, Brian Lim
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.