A registry to improve the lives of stroke survivors in South London

The South London Stroke Register: Improving the Lives of Stroke Survivors With Data

Observational Guy's and St Thomas' NHS Foundation Trust · NCT05298436

This study is tracking stroke survivors in South London to see how their health and quality of life change over time.

Quick facts

Study typeObservational
Enrollment2000 (estimated)
Ages18 Years and up
SexAll
SponsorGuy's and St Thomas' NHS Foundation Trust Academic / other
Locations7 sites (London and 6 other locations)
Trial IDNCT05298436 on ClinicalTrials.gov

What this trial studies

The South London Stroke Register is an observational registry that tracks stroke events and outcomes in a defined area of South London. It combines a population incidence study with a cohort study, following patients over time to gather data on health outcomes, quality of life, and mental health. The registry has been ongoing since 1995 and will now incorporate the new ICD-11 definition for stroke case identification. Participants will be regularly interviewed for up to 15 years post-stroke to assess long-term outcomes.

Who should consider this trial

Good fit: Ideal candidates are individuals who have experienced their first stroke since January 1, 1995, and reside in the designated study area of South London.

Not a fit: Patients who had their first stroke before January 1, 1995, or those living outside the study area will not benefit from this registry.

Why it matters

Potential benefit: If successful, this registry could lead to improved care and support for stroke survivors, enhancing their quality of life and health outcomes.

How similar studies have performed: Other observational stroke registries have shown success in improving patient outcomes and understanding stroke epidemiology, indicating that this approach is both tested and valuable.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Confirmed stroke (WHO ICD-11 clinical definition)- cerebral ischaemic stroke, primary intracerebral haemorrhage, subarachnoid haemorrhage and stroke not known if ischaemic or haemorrhagic. Formerly defined Transient Ischaemic Attacks with CT/MRI evidence of cerebrovascular disease are classified as stroke under this definition.
2. Living in the study area at the time of the first stroke.
3. First stroke since 1st January 1995 for enrolled participants. First stroke since 1st April 2022 for updated definition.

Exclusion Criteria:

1. First ever stroke is before 1st January 1995
2. Patients' main residence at the time of first stroke is outside the study area.
3. Focal neurological signs resolved within 24 hours and no CT/MRI scan reports evidence of cerebrovascular disease (i.e. transient ischaemic attack)
4. CT/MRI scans positive for cerebrovascular disease but absence of related focal neurological deficits (asymptomatic cerebrovascular disease)
5. brain lesion other than stroke causes the acute symptoms such as cerebral tumour or metastases

Where this trial is running

London and 6 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions StrokeSubarachnoid HemorrhageIntracranial HemorrhagesRegistriesEpidemiologyCohort study
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.