Identifying blood markers for brain complications after a type of stroke.
Official title: Biomarker Signatures for Delayed Cerebral Ischemia and Outcome Following Subarachnoid Hemorrhage
Funded at University of California at Davis · NIH-11030271 · Data updated 2026-11-12
This study is looking at how certain blood markers can help doctors figure out which patients who have had a brain bleed might face complications later on, so they can get the right care sooner and improve their recovery.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project start | January 1, 2021 |
| Project end | January 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $543,342 |
| NIH project number | 5R33NS119345-05 |
| Project ID | NIH-11030271 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have recently suffered a subarachnoid hemorrhage.
✕Less likely to help
Patients who have not experienced a subarachnoid hemorrhage or those with other types of strokes may not benefit from this research.
What this research studies
This research investigates how specific blood markers can predict the risk of delayed cerebral ischemia (DCI) in patients who have experienced a subarachnoid hemorrhage (SAH). By analyzing gene expression and inflammatory molecules in the blood, the study aims to understand how these factors interact with the brain's blood vessels to cause complications. The goal is to identify patients at risk for DCI early, allowing for timely interventions that could improve outcomes. This approach combines advanced biomarker analysis with clinical insights to enhance patient care.
Why it matters
Potential benefit: If successful, this research could lead to improved prediction and management of brain complications in stroke patients, potentially reducing mortality and long-term disability.
How similar studies have gone: Previous research has shown promise in using blood biomarkers to predict complications in stroke patients, suggesting that this approach may be effective.
Where this research is happening
-
University of California at Davis
Davis, United States Active
Researchers
- Principal investigator: Sharp, Frank R — University of California at Davis
- Study coordinator: Sharp, Frank R
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.