Condition
Intracerebral Hemorrhage clinical trials and research
As of November 12, 2026, Find a Trial lists 56 Intracerebral Hemorrhage clinical trials that are recruiting, at sites in 24 countries (most in China (20), United States (17), Hong Kong (6)). 2 were first registered in the last 30 days. By phase: Phase 3 (7), Phase 4 (3), Phase 2 (2), Phase 1 (1). The most active sponsors are Beijing Tiantan Hospital (5), The University of Hong Kong (4), The George Institute (2). There are also 29 NIH-funded research projects on Intracerebral Hemorrhage, with $17.5 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 56Clinical trials
- 29NIH research projects
- 2New in 30 days
- 24Countries
Newest Intracerebral Hemorrhage clinical trials
All recruiting trials (56)
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AI-based tools to help diagnose, treat and predict stroke outcomes across multiple hospitals
This study tests AI-powered tools on real-world stroke patients to see if they can improve pre-hospital triage, diagnosis, and outcome prediction while data stay securely within each hospital.
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Smartphone-based EEG to detect hidden awareness in ICU patients with brain injuries
Researchers will test a smartphone-enabled EEG to see if it can reveal Cognitive Motor Dissociation in ICU patients who can’t show commands at bedside.
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Chinese multicenter group studies spontaneous intracerebral hemorrhage in adults
This study tests how a large group of adults with spontaneous intracerebral hemorrhage (and a healthy control group) progress over time to understand outcomes and determinants of recovery.
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Rapid Evacuation and Access of Cerebral Hemorrhage Registry: observing minimally invasive surgery outcomes
This registry collection tests how minimally invasive brain-bleed procedures work in real patients with acute spontaneous intracerebral hemorrhage.
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Single triple-combination blood pressure pill after intracerebral hemorrhage
This trial tests whether a single pill combining amlodipine, valsartan, and hydrochlorothiazide helps adults who recently had an intracerebral hemorrhage control their blood pressure.
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Vitamin D treatment after intracerebral hemorrhage
This will try giving higher-dose vitamin D to adults within 96 hours of an intracerebral hemorrhage to see if it helps clear the bleed faster and is safe.
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Prototype CT tools for minimally invasive intracerebral hemorrhage evacuation
This project will test two Siemens prototype CT tools—a perfusion feature and an automatic hemorrhage detector—to see if they help doctors planning and performing minimally invasive brain-bleed (intracerebral hemorrhage) evacuation in adults.
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Ex Vivo Hematoma Thrombolysis With Modified rtPA for ICH
This study tests whether a modified tissue plasminogen activator can help dissolve blood clots outside the body using blood samples from people with and without bleeding risk factors.
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Augmented kidney clearance in neurocritical care
This project will test whether adults in the neuro-ICU with severe brain injury, stroke, seizures, or brain infections have faster kidney clearance (ARC) that can lower antiseizure and antibiotic drug levels.
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Precision use of tranexamic acid for intracerebral hemorrhage
This study will try giving intravenous tranexamic acid to adults with certain supratentorial intracerebral hemorrhages within 6 hours to see if it limits hematoma growth and improves recovery.
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Minocycline treatment for acute spontaneous intracerebral hemorrhage.
This trial will test whether a five-day course of oral minocycline started within 48 hours helps adults with moderate supratentorial intracerebral hemorrhage recover better by 90 days.
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AI-assisted transcranial Doppler ultrasound to detect early brain bleeding
This will try to see if a quick transcranial Doppler ultrasound combined with artificial intelligence can detect intracerebral bleeding in adults with suspected acute stroke within 48 hours of symptom onset.
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Bladder Temperature-Guided Temperature Management in Intracerebral Hemorrhage
This study tests whether using bladder temperature monitoring to guide temperature management helps adults with severe intracerebral hemorrhage recover better than standard temperature monitoring.
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Non-invasive ultrasound to speed hematoma clearance after intracerebral hemorrhage
This trial tests whether daily non-invasive ultrasound sessions added to standard care help people with supratentorial intracerebral hemorrhage clear the bleed faster and improve recovery.
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INTERACT4 Expansion: Seeing if a quick GFAP test can help ID brain bleeds before hospital care
This observational study tests whether a point-of-care GFAP test in pre-hospital care can help identify intracerebral hemorrhage in adults with suspected acute stroke.
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Recombinant factor VIIa treatment for acute intracerebral hemorrhage
This trial will try recombinant factor VIIa in adults with spontaneous intracerebral hemorrhage to see if very early treatment reduces bleeding and improves 90‑day outcomes.
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Early minimally invasive catheter evacuation with thrombolysis for intracerebral hemorrhage
This trial tests whether early minimally invasive catheter clot removal combined with thrombolysis helps adults with acute spontaneous supratentorial intracerebral hemorrhage (≥20 mL) recover better than best medical care.
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When and how people recover after an intracerebral hemorrhage
This registry will collect detailed, long-term data on adults who have surgery for intracerebral hemorrhage to see if the timing and type of surgical treatment affect recovery and quality of life.
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AI-guided hematoma aspiration versus conservative drug therapy for spontaneous intracerebral hemorrhage
This trial will test whether AI-assisted, navigation-guided hematoma aspiration or targeted pharmacological therapy leads to better recovery for people with moderate-volume spontaneous supratentorial intracerebral hemorrhage.
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Noninvasive ear vagus nerve stimulation for acute intracerebral hemorrhage
This trial will test whether gentle electrical stimulation of the ear (taVNS) can reduce swelling around a recent intracerebral hemorrhage in adults treated within 72 hours of symptom onset.
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Understanding brain and heart injuries after bleeding in the brain
This study looks at how bleeding in the brain affects both the brain and the heart in adults to better understand the connection between these injuries.
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Stem cell therapy for subacute intracerebral hemorrhage
This study tests human umbilical cord mesenchymal stem cells given through the bloodstream to see if they are safe and helpful for people with a subacute intracerebral hemorrhage.
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Using a new endoscope to treat brain bleeding
This study is testing a new type of endoscope to see if it can safely and effectively help people with brain bleeding by removing blood clots.
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Optimizing care for patients with non-traumatic intracerebral hemorrhage
This study is testing a new emergency care plan for patients with non-traumatic brain bleeding to see if it can improve their treatment and recovery.
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Using auricular vagus nerve stimulation to improve outcomes after brain bleeding
This study is testing if a new type of ear stimulation can help people recover better and have fewer complications after bleeding in the brain.
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Investigating the effects of stellate ganglion block on retinal blood flow
This study is testing if a special nerve block used for pain relief can improve blood flow in the eyes of patients with severe brain injuries.
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Comparing treatments for acute intracerebral hemorrhage to prevent secondary brain injury
This study is testing if giving certain medications early can help prevent further brain damage in people with a type of bleeding in the brain.
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Timing of anticoagulation for preventing blood clots in patients with brain hemorrhage
This study is testing whether starting blood-thinning treatment early or later can help prevent blood clots in patients with bleeding in the brain while keeping them safe from more bleeding.
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Emergency Stroke Unit for treating acute strokes
This study is testing a new Emergency Stroke Unit that uses a mobile MRI to see if it can help treat stroke patients faster and improve their recovery.
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Monitoring heart function in patients with brain injuries
This study looks at how heart function affects recovery in people with brain injuries by tracking their health data after they leave the hospital.
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Minimally invasive procedure for brain hemorrhage evacuation
This study is testing a new, less invasive surgery for brain bleeding to see if it helps adults with certain types of hemorrhages do better than traditional surgery methods.
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Fufang Congrong Yizhi Capsules for cognitive impairment after brain surgery
This study is testing whether Fufang Congrong Yizhi Capsules can help people with memory problems after brain surgery feel better compared to standard treatment alone.
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Observational study of patients with spontaneous intracerebral hemorrhage
This study is looking at patients with spontaneous brain bleeding to see how they recover and what long-term effects they might have.
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Observational study on outcomes of primary intracerebral hemorrhage in hospitalized adults
This study looks at hospitalized adults with bleeding in the brain to see how common it is, what treatments they get, and how well they do after being treated.
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Identifying biomarkers and imaging markers for intracerebral hemorrhage
This study is trying to find new blood and imaging tests that can help doctors better understand and treat patients who have had a severe type of stroke called intracerebral hemorrhage.
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Understanding quality of life and stress in stroke patients and their caregivers
This study looks at how stroke affects the quality of life and stress levels in both patients and their caregivers to see how they compare to people without stroke.
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Care bundle to improve recovery after intracerebral haemorrhage
This trial will try a structured treatment package—rapid reversal of blood thinners when needed, early intensive blood pressure lowering, and treatment of fever and high blood sugar—to see if it improves 3‑month outcomes for adults with spontaneous intracerebral haemorrhage who arrive within 24 hours of symptom onset.
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Clevidipine to control high blood pressure after acute intracerebral hemorrhage
This trial will test whether IV clevidipine helps adults with acute intracerebral hemorrhage reach and keep their target systolic blood pressure within 60 minutes better than other IV blood-pressure medicines.
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Non-invasive measurement of brain pressure in patients with traumatic brain injury
This study is testing a new non-invasive device to measure brain pressure in patients with traumatic brain injury to see if it can replace the need for more risky surgical methods.
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Impact of neurochecks on cognitive outcomes in older patients with brain injury
This study is testing if changing how often older patients with brain injuries get neurological checks in the ICU can help them think better and reduce confusion.
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Treatment of brainstem cavernous malformations with sirolimus
This study is testing if the drug sirolimus can help people who have had bleeding in the brain due to brainstem cavernous malformations by reducing the chances of more bleeding.
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Registry of brain-heart comorbidity in China
This study is trying to build a big database to better understand and manage the connection between brain and heart problems in people across China.
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Mobile health intervention for managing hypertension in ICH survivors
This study is testing a mobile health program to see if it helps people who have survived a brain bleed manage their high blood pressure better than regular doctor visits.
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Using apixaban to prevent strokes in patients with severe kidney disease and atrial fibrillation
This study is testing if the blood thinner apixaban can help prevent strokes in people with severe kidney disease and atrial fibrillation.
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Identifying treatment targets for bleeding in patients with spontaneous brain hemorrhage
This study is testing if a special imaging technique can help find the source of bleeding in patients with sudden brain hemorrhages to improve their treatment options.
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Minimally invasive surgery for intracerebral hemorrhage
This study is testing if early minimally invasive surgery can help people with brain bleeding feel better when done within 8 hours of their symptoms starting.
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Effects of Celecoxib on Intracerebral Hemorrhage
This study is testing if the medication celecoxib can help improve recovery for people who have had bleeding in the brain from an intracerebral hemorrhage.
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Observational study of stroke management and outcomes at Akershus University Hospital
This study looks at how patients with strokes are treated at Akershus University Hospital to see how well different treatments work and why some patients don’t receive certain therapies.
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Using ketamine to treat severe acute brain injuries
This study is testing if S-ketamine can help people with severe brain injuries feel better and improve their recovery compared to a placebo.
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Using antibiotics with external ventricular drains to prevent infections
This study tests whether giving antibiotics for 24 hours or for the whole time a patient has an external ventricular drain can help prevent infections in people with brain bleeding.
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Understanding cognitive changes after stroke
This study is trying to find out what affects thinking and memory changes in people who have had a stroke, to help improve recovery in the future.
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Observational study on intracerebral hemorrhage in hospitalized adults
This study is trying to learn more about adults in the hospital with brain bleeding to better understand their treatment options and outcomes.
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Understanding recovery after brain hemorrhage
This study looks at how different types of brain bleeding affect recovery and how treatments in the hospital can impact patient outcomes for people with serious brain injuries.
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Evaluating statin use after brain hemorrhage
This study is testing whether people who have had a brain bleed should keep taking their statin medications to see if it helps prevent more brain bleeds and other serious health problems.
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Comparing apixaban and aspirin for preventing strokes in ICH survivors with atrial fibrillation
This study is testing if a blood thinner called apixaban works better than aspirin to prevent strokes or death in people who have had a brain bleed and also have atrial fibrillation.
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Comparing anticoagulation strategies after brain hemorrhage in patients with atrial fibrillation
This study is testing three different ways to prevent future blood clots in people with atrial fibrillation who have had a brain bleed to see which method works best.
NIH-funded research (29)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Anticoagulation in ICH Survivors with Atrial Fibrillation and Small Vessel Disease
This project looks at how to safely use blood-thinning medicines in people who survived a brain bleed and also have atrial fibrillation and small vessel disease.
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Statin use after lobar intracerebral hemorrhage
This trial compares continuing versus stopping statins in people who had a lobar intracerebral hemorrhage to see how that affects repeat brain bleeds, strokes, heart attacks, and recovery over two years.
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Statin use after lobar brain hemorrhage
This trial compares stopping versus continuing statin medicine in people who had a lobar brain bleed to learn effects on repeat bleeding and future heart or stroke events.
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Blocking red blood cell death after brain hemorrhage
A study at Yale is exploring whether stopping a specific kind of red blood cell death after a brain hemorrhage could improve recovery.
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Targeting HDAC3 to reduce brain damage after a brain bleed
This project will test whether blocking a protein called HDAC3 can reduce inflammation and improve recovery after an intracerebral hemorrhage (brain bleed).
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Silent brain injuries after brain bleed may predict dementia risk
A study using MRI and cognitive tests to see if hidden brain injuries after spontaneous intracerebral hemorrhage help forecast later cognitive decline.
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Tracking how stem cells and their tiny vesicles move in a mouse model of brain bleed
A study in mice will map how stem cells and their extracellular vesicles distribute in the brain after an intracerebral hemorrhage to better understand how they could help repair the damaged brain.
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Anticoagulation in ICH survivors with AF and small vessel disease features
A study to understand how anticoagulant therapy affects people who have had a non-traumatic brain bleed and also have atrial fibrillation, focusing on imaging signs of small vessel disease.
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Statin use after lobar intracerebral hemorrhage
This trial compares continuing versus stopping statin medicines for people who had a lobar brain bleed and were taking statins.
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Targeting immune cells to prevent brain AVM bleeding from KRAS mutations
Looks at whether calming immune cells around brain arteriovenous malformations can lower the risk of life‑threatening brain bleeds in people whose AVMs are linked to KRAS mutations.
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Blocking RIPK1 to prevent thinking problems after a brain hemorrhage
This research tests whether stopping a protein called RIPK1 can prevent memory and thinking problems that often develop after bleeding in the brain.
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Stopping a toxic zinc compound after a brain bleed
Aiming to prevent a harmful zinc-containing molecule that forms after a brain bleed to protect people who have had an intracerebral hemorrhage.
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Blood marker to predict and track worsening brain injury after a spontaneous brain bleed
This project looks at a blood marker called DEspR+CD11b+ neutrophils to help predict or track worsening brain injury in people after a spontaneous intracerebral hemorrhage.
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Hidden small strokes after a brain bleed and risk of thinking and memory problems
This project looks at whether hidden small strokes seen on MRI after a spontaneous brain bleed predict thinking and memory problems in survivors.
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Investigating anticoagulation therapy for stroke survivors with specific brain conditions
This study is looking at how brain health affects the safety and success of blood-thinning treatments for people who have had a specific type of stroke and also have a heart condition, to help doctors make better treatment choices for these patients.
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Investigating the use of statins in patients with brain hemorrhage
This study is looking to find out if people who have had a certain type of brain bleed should keep taking their cholesterol-lowering medication, called statins, or stop taking them, and it will help us understand how this choice affects their chances of having another brain bleed or heart problems over two years.
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Targeting immune cells to prevent bleeding in brain malformations
This study is looking at how certain immune cells might affect the risk of bleeding in people with brain arteriovenous malformations (bAVMs), and it aims to find new ways to help prevent these dangerous complications.
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Investigating silent brain infarcts in patients with spontaneous brain hemorrhage and their link to cognitive decline.
This study is looking at people who have survived a brain bleed to see if hidden brain damage might be affecting their thinking skills, with the hope of finding clues that could help doctors better support their brain health in the future.
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Investigating the role of zinc protoporphyrin in brain damage after bleeding in the brain
This study is looking at how a substance called zinc protoporphyrin (ZnPP) affects brain damage after a type of bleeding in the brain, hoping to find new ways to help people recover better from this condition.
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Understanding how specific immune cells respond after a brain hemorrhage
This study is looking at how certain immune cells in the brain might help people recover after a serious type of stroke called intracerebral hemorrhage, using mice to see when these cells show up and how they could support healing over 16 weeks.
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Identifying a blood biomarker for brain injury after spontaneous bleeding in the brain
This study is looking at a specific blood marker that could help doctors predict and track brain injury in people who have had a serious type of stroke called spontaneous intracerebral hemorrhage, so they can better understand how to treat and monitor their recovery.
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Investigating how brain hemorrhage affects tissue damage and recovery using MRI.
This study is looking at how bleeding in the brain affects brain tissue over time using special MRI scans, to help us understand recovery and find better treatments for people who have had a brain bleed.
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Investigating a protein's role in dementia after brain bleeding.
This study is looking at how a protein called RIPK-1 might play a role in memory problems for younger people who have had a brain bleed, with the goal of finding ways to help prevent dementia in these patients.
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Investigating a new treatment for brain injuries caused by bleeding in the brain.
This study is looking at how a new medication called MW189 can help people who have had serious brain injuries from bleeding in the brain, by reducing inflammation and hopefully helping them recover better.
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Using remote ischemic conditioning to help recovery after brain hemorrhage
This study is looking at how a special treatment called remote ischemic conditioning might help people recover better after a serious type of stroke called intracerebral hemorrhage by promoting healing in the brain and improving brain function.
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How red blood cells affect bleeding and oxygen levels in brain hemorrhage patients
This study is looking at how low levels of red blood cells might affect recovery for people who have had a type of stroke called intracerebral hemorrhage, and it aims to find better ways to help these patients heal and avoid complications.
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A robot designed to remove blood clots from the brain using MRI technology
This study is working on a special robot that can gently remove blood clots from the brain while you’re having an MRI, making it easier for doctors to see what they’re doing and help you get better.
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Understanding how the aging brain changes after a type of stroke called intracerebral hemorrhage
This study is looking at how the aging brain changes after a serious stroke called intracerebral hemorrhage, to help us understand why older adults may struggle more with recovery, and it aims to find better treatment options for them.
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Understanding recovery of consciousness after brain hemorrhage
This study is looking at how people who have had a brain hemorrhage and show signs of being aware can recover their consciousness, using a simple brain test to help understand their progress and find better ways to support their recovery.
Related topics
Quick answers
How many Intracerebral Hemorrhage clinical trials are recruiting right now?
56, as of November 12, 2026. 2 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 24 countries. The most sites are in China (20 trials), United States (17 trials), Hong Kong (6 trials), Canada (4 trials), Australia (3 trials). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 3: 7, Phase 4: 3, Phase 2: 2, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.