Condition

Myopia clinical trials and research

• 89Clinical trials
• 40NIH research projects
• 24Countries

Newest Myopia clinical trials

All recruiting trials (89)

• Hyperopic reserve screening for kindergartners in Beijing

  A population-wide screening tests whether senior kindergarten children in Beijing have enough hyperopic reserve to help prevent future myopia.

  Recruiting Beijing Tongren Hospital · Beijing · NCT07851532

• Do dual-focus multifocal contact lenses improve hand-eye coordination and sports vision compared with your usual lenses

  This study tests whether wearing dual-focus multifocal contact lenses improves hand-eye coordination and sports vision in adults who play baseball or softball and normally wear contact lenses.

  Recruiting Ohio State University · Columbus, Ohio · NCT07840209

• Two monthly silicone hydrogel multifocal toric contact lenses in wearers with astigmatism and myopia

  This study tests whether two popular soft multifocal toric contact lenses perform differently in adults who need vision correction for astigmatism and myopia.

  Recruiting CooperVision International Limited (CVIL) · New York, New York and 2 other locations · NCT07829419

• Seeing clearly in low light after Ray-Tracing guided LASIK

  A trial tests how well WaveLight Plus LASIK works for people with myopia and astigmatism and whether patients are satisfied after the procedure.

  Recruiting Phase 4 Vance Thompson Vision · Sioux Falls, South Dakota · NCT07790185

• AI-assisted DIMS glasses to stop myopia in young children with pre-myopia

  This trial tests whether AI-assisted DIMS-style glasses can help prevent myopia in children aged 3–6 who are at risk.

  Recruiting Shanghai Eye Disease Prevention and Treatment Center · Shanghai, Shanghai Municipality · NCT07765550

• See how streetscape exposure might influence kids’ vision and perceptions

  This study tests whether a virtual street environment affects how children with and without myopia perceive visual and psychological cues.

  Recruiting Zhongshan Ophthalmic Center, Sun Yat-sen University · Guangzhou, Guangdong · NCT07761949

• Orthokeratology contact lenses with a 5 mm optic zone diameter

  This study tests Paragon CRT lenses with a 5 mm optic zone in kids and young adults to see how well they fit, how well they vision, and how comfortable they are at night.

  Recruiting at 2 sites CooperVision International Limited (CVIL) · Pleasanton, California and 2 other locations · NCT07751172

• Auricular Acupressure to Help Prevent Myopia in Young Kids With Limited Hyperopic Reserve

  This trial tests whether auricular acupressure, added to standard eye health education, can help prevent myopia in elementary students who don’t have enough hyperopic reserve.

  Recruiting Shanghai Eye Disease Prevention and Treatment Center · Shanghai, Shanghai Municipality · NCT07746804

• Myopia control for kids using defocus lenses with ear acupressure in school

  This trial tests whether adding auricular acupressure to defocus spectacle lenses can better slow myopia progression in primary school children with premyopia or myopia.

  Recruiting Shanghai Eye Disease Prevention and Treatment Center · Shanghai, Shanghai Municipality · NCT07746778

• Outdoor activity program with wearable support to help prevent myopia in schoolchildren with good hyperopic reserve

  A school-based program using a wearable device to promote outdoor activity is tested to see if it can help prevent myopia in kids in grades 1–4 who have adequate hyperopic reserve.

  Recruiting Shanghai Eye Disease Prevention and Treatment Center · Shanghai, Shanghai Municipality · NCT07746752

• SMILE in one eye vs Ray tracing-guided LASIK in the fellow eye

  This study tests two laser vision correction methods—SMILE in one eye and ray-tracing guided LASIK in the other eye—to see which provides better vision and quality of life for adults with myopia and astigmatism.

  Recruiting Phase 4 Stanford University · Palo Alto, California · NCT07721714

• Using DIMS Glasses to See if Myopia Progression Slows in Kids

  This observational study tests whether wearing DIMS glasses in children and teens with myopia can slow progression, considering factors like outdoor time and family history.

  Recruiting Semmelweis University · Budapest · NCT07698977

• Understanding how vision affects daily life for kids with myopia in Sweden

  This study tests a new Swedish questionnaire to see how vision problems like myopia affect kids’ everyday life and makes sure it works well for patients.

  Recruiting Region Örebro County · Örebro · NCT07653074

• Longitudinal Visual Diet in Children

  This study follows children ages 7–12 to see how everyday visual factors like distance, light, and viewing patterns relate to myopia development over time.

  Recruiting State University of New York College of Optometry · New York, New York · NCT07642999

• Delay nearsightedness in high-risk children with nightly low-dose eye drops

  This will test whether giving children ages 6–11 nightly 0.05% atropine eye drops delays the start of nearsightedness compared with nightly placebo drops.

  Recruiting at 12 sites Phase 3 Ohio State University · Birmingham, Alabama and 12 other locations · NCT07567040

• County-centered eye health service model for rural children in China

  This project tests whether a county-centered, integrated eye health service can improve vision screening, spectacle correction, and referral outcomes for children aged 3–18 in several rural Chinese counties.

  Recruiting Zhongshan Ophthalmic Center, Sun Yat-sen University · Lincang, Yunnan · NCT07547748

• Myopia control with two novel soft contact lenses in children

  This study tests whether two new soft contact lenses can better slow myopia progression in children aged 7–12 compared with standard single-vision lenses.

  Recruiting The Hong Kong Polytechnic University · Kowloon, Hong Kong · NCT07547085

• Modified DIMS glasses for myopia in children

  This study tests whether two versions of modified DIMS spectacle lenses can influence choroidal thickness and eye growth in 6- to 13-year-olds with myopia.

  Recruiting The Hong Kong Polytechnic University · Kowloon, Hong Kong · NCT07547072

• Targeted Lens Intervention for Anisometropia in Children

  We’re testing if research spectacles can reduce the difference in prescription between a child’s eyes when one eye is more myopic than the other.

  Recruiting Essilor International · Singapore · NCT07533149

• T10430 eye drops to slow childhood myopia progression

  We will test whether T10430 eye drops can slow worsening nearsightedness in children aged 6 to 11.

  Recruiting at 2 sites Phase 2 Laboratoires Thea · Amman and 9 other locations · NCT07522242

• Does intraoperative kappa-angle compensation improve vision after SMILE for small kappa offsets?

  This trial tests whether compensating for the kappa-angle during SMILE surgery improves postoperative vision and optical quality for adults with mild myopia.

  Recruiting Zhongshan Ophthalmic Center, Sun Yat-sen University · Guangzhou, Guangdong · NCT07512115

• Low vs high kappa-angle compensation during SMILE with VisuMax 800

  This trial tests whether using a low (50%) or high (100%) kappa-angle compensation during SMILE surgery with the VisuMax 800 produces better postoperative vision for adults with myopia and large kappa offsets.

  Recruiting Zhongshan Ophthalmic Center, Sun Yat-sen University · Guangzhou, Guangdong · NCT07512102

• SMILE with VISUMAX 500 versus VISUMAX 800 for correcting short-sightedness

  We will try SMILE eye surgery with the newer VISUMAX 800 on one eye and the VISUMAX 500 on the other to see which gives better vision and recovery for people with myopia.

  Recruiting Singapore Eye Research Institute · Singapore · NCT07505264

• How teenagers with and without myopia hold things and move when wearing different eyeglass prescriptions

  This study will test whether different eyeglass prescriptions, including Stellest lenses, change how close teenagers hold objects and how they move during everyday near tasks.

  Recruiting Essilor International · Paris · NCT07440134

• DYMOND: TrackSight peripheral-vision myopia control for children

  This study will see if TrackSight, an eye-tracking app, can slow nearsightedness progression in children aged 6–12 during their regular screen use.

  Recruiting Phase 2 NovaSight · Rehovot · NCT07390500

• Focused LED red-light treatment for adults with nearsightedness

  This pilot tests whether short, home-based red LED light sessions can thicken the choroid and boost choroidal blood flow in adults ages 18–50 with mild to moderate myopia.

  Recruiting The Hong Kong Polytechnic University · Hong Kong, Hong Kong · NCT07369804

• A.M.L. spectacle lenses for children with myopia

  We will try A.M.L. spectacle lenses in 6- to 12-year-old children with myopia to see how quickly they adapt and how comfortable the lenses feel.

  Recruiting Essilor International · Shanghai, Shanghai Municipality · NCT07354945

• Adaptation and tolerance of Essilor Stellest lenses in children with progressive myopia

  This observational pilot tests how well children with progressive myopia adapt to and tolerate Essilor Stellest lenses in real life.

  Recruiting Nantes University Hospital · Nantes, Nantes · NCT07340931

• Onset of myopia in children who are not yet myopic

  This study follows children aged 4 to under 9 with no myopia to see how many become nearsighted over time and what factors might influence that shift.

  Recruiting Fondation Ophtalmologique Adolphe de Rothschild · Paris · NCT07316998

• Where children look through their glasses

  This trial tests how children ages 7–14 look through a new spectacle lens design to see which parts of the lens they use during different tasks.

  Recruiting SightGlass Vision, Inc. · Bloomington, Indiana · NCT07229365

• Children wearing spectacle lenses: mobility during everyday activities

  This test checks whether myopia-control spectacle lenses change how children aged 6–12 move and perform everyday mobility tasks compared with regular single-vision glasses.

  Recruiting SightGlass Vision, Inc. · Glendale, Arizona · NCT07229352

• Comparing Ray‑Tracing Guided LASIK with three other laser vision correction methods for myopia and astigmatism

  This test will compare Ray‑Tracing Guided LASIK to three other laser or lenticule refractive procedures for adults with moderate myopia, with or without astigmatism.

  Recruiting Hoopes Vision · Draper, Utah · NCT07201298

• Preventing early childhood myopia with special spectacle lenses and low-dose atropine

  This project will try spectacle lenses with highly aspherical lenslets and low-dose (0.01% and 0.05%) atropine eye drops to see if they slow myopia progression in children aged 3–6.

  Recruiting Shanghai Eye Disease Prevention and Treatment Center · Shanghai, Shanghai Municipality · NCT07176949

• AO-SLO repeatability and cone cell density after repeated low-intensity red-light therapy

  This test will see whether a high-resolution eye imaging device (AO-SLO) gives consistent cone cell density measurements and whether people with myopia aged 6–55 who used repeated low-intensity red-light therapy have different cone density.

  Recruiting Tianjin Medical University Eye Hospital · Tianjin, Tianjin Municipality · NCT07160036

• Choroidal thickness change after 1 hour wearing prototype soft contact lenses

  This test will see if three prototype soft contact lenses change choroidal thickness in people aged 18 to 25 with myopia.

  Recruiting Myoptechs, Inc · Waterloo, Ontario · NCT07155551

• My Eyes, My Light — community eye screening in Char Fasson

  This project tests whether a community-based screening program can find treatable eye problems in people aged 35 and older who live in Char Fasson, Bangladesh.

  Recruiting Data Yakka, Inc. · Char Fasson, Bhola · NCT07135570

• WaveLight Plus LASIK for nearsightedness and astigmatism

  This study will try WaveLight Plus LASIK in adults with nearsightedness and astigmatism to see if it improves vision, satisfaction, and quality of life over three months.

  Recruiting Laser Defined Vision · Greensboro, North Carolina · NCT07127757

• Spectacles with special lenslets and low-dose atropine for slowing myopia in kids

  This study tests whether nightly 0.05% atropine drops and specially designed glasses with aspherical lenslets can slow myopia progression in children aged 5 to under 12.

  Recruiting at 18 sites Phase 3 Jaeb Center for Health Research · Birmingham, Alabama and 17 other locations · NCT07095894

• Contact lens lubricant for rigid gas-permeable (OK) lens wearers

  This trial will test whether LACRIFRESH OCU-DRY 0.3% eye drops help rigid gas-permeable (OK) contact lens wearers feel more comfortable and keep good distance vision.

  Recruiting at 3 sites Avizor SA · Beijing, Beijing Municipality and 2 other locations · NCT07091825

• Wavefront-guided LASIK versus ray-tracing-guided LASIK in opposite eyes

  We will try wavefront-guided LASIK in one eye and ray-tracing-guided LASIK in the other eye of adults 22 and older with nearsightedness (with up to 3 diopters of astigmatism) to see if one gives better vision outcomes.

  Recruiting Stanford University · Palo Alto, California · NCT07078799

• Genetic links to myopia in children and adolescents

  The team will test whether specific gene variants influence myopia risk and progression in children and adolescents and whether those genes change how well treatments like low‑dose atropine drops, orthokeratology lenses, specialty glasses, or more outdoor time work.

  Recruiting at 2 sites Beijing Visionly Plus Eye Hospital · Beijing and 1 other locations · NCT07030153

• Low-dose atropine eye drops to slow myopia in children and adolescents

  This study will try low-dose atropine eye drops (0.025% and 0.05%) versus placebo to see if they slow myopia progression in children and adolescents aged 3 to 17 over 24 months.

  Recruiting at 10 sites Phase 3 Ocus Innovation Ireland Limited · Tirana and 10 other locations · NCT07028827

• Wearability and myopia control with ZEISS MyoCare versus ZEISS single‑vision spectacle lenses

  This test will see if ZEISS MyoCare spectacle lenses, compared with two ZEISS single‑vision lenses, slow myopia progression in children aged 7 to 13.

  Recruiting ZEISS Vision Care · Hanoi · NCT07021560

• Continued use of DOT spectacle lenses for Chinese children

  This will test whether DOT spectacle lenses slow myopia progression over 12 months in Chinese children who completed the earlier CATHAY study.

  Recruiting at 4 sites SightGlass Vision, Inc. · Changsha and 4 other locations · NCT07008001

• Brimonidine Eye Drops to Slow Myopia in Kids

  A small study will test whether brimonidine eye drops can slow myopia progression in children ages 6–14.

  Recruiting Phase 2 Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal · Madrid, Madrid · NCT06996236

• Virtual Far-sight Reading Device for Pre-myopia in Children

  A device-guided reading program is tested to see if it can slow or prevent myopia in kids with pre-myopia and if it's safe with daily use for up to 6 months.

  Recruiting Shanghai Eye Disease Prevention and Treatment Center · Shanghai · NCT06995911

• Longitudinal analysis of spine and vision health in adolescents in Zhejiang

  This study looks at how common scoliosis and vision problems are in kids and teens aged 6-18 in Zhejiang, and tracks changes in their spine and eyesight over eight years while providing health education to help catch issues early.

  Recruiting Second Affiliated Hospital of Wenzhou Medical University · Wenzhou, Zhejiang · NCT06992622

• Comparing SMILE and SMILE Xtra procedures for myopia treatment

  This study is testing which of two eye surgeries, SMILE or SMILE Xtra, works better for treating nearsightedness and keeping your vision stable.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT06992011

• Optimizing SMILE surgery for correcting vision problems

  This study is testing if using a new system for SMILE eye surgery can help patients see better after the procedure compared to the traditional method.

  Recruiting Affiliated Hospital of Nantong University · Nantong, Jiangsu and 1 other locations · NCT06982807

• Comparing the effectiveness of two treatments for myopia

  This study is testing which of two eye surgeries, SMILE or SMILE Xtra, works better for people aged 18 to 50 with high myopia to improve their vision and keep it stable over time.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT06973278

• Observing eye growth in children with myopia

  This study looks at how myopia, or nearsightedness, changes in children in France to help find better ways to prevent it.

  Recruiting Fondation Ophtalmologique Adolphe de Rothschild · Paris · NCT06895044

• Evaluating a device for screening vision problems in young children

  This study is testing a new device to see if it can effectively find vision problems in children aged 3 to 8, whether they wear glasses or not.

  Recruiting Essilor International · Nancy, France and 1 other locations · NCT06882408

• Evaluating a device for screening vision problems in young children

  This study is testing a new device to see if it can effectively find vision problems in children aged 3 to 8, whether they wear glasses or not.

  Recruiting Essilor International · Nancy, France and 1 other locations · NCT06882408

• Spectacle lens with passive red light to slow myopia in children

  This will test whether glasses that emit passive red light can slow myopia progression in children aged 6 to 11.

  Recruiting Essilor International · Singapore · NCT06850168

• Comparing defocus-enhanced and single vision spectacles for myopia control in children

  This study tests whether special glasses that blur the vision a little can help kids aged 6 to 18 with myopia control their eyesight better than regular glasses.

  Recruiting at 2 sites Beijing Visionly Plus Eye Hospital · Beijing and 1 other locations · NCT06821074

• Rodenstock spectacle lenses to slow myopia progression in children

  This will test whether Rodenstock myopia-control spectacle lenses can slow myopia progression in children aged 6–12 over two years.

  Recruiting Rodenstock GmbH · Singapore · NCT06816446

• Comparing three methods for correcting myopia

  This study tests three different ways to correct nearsightedness to see which one works best and makes patients the happiest.

  Recruiting at 2 sites Beijing Visionly Plus Eye Hospital · Beijing and 1 other locations · NCT06788418

• Comparing two laser procedures for treating myopia

  This study is testing two different laser treatments for nearsightedness to see which one works better and has fewer side effects.

  Recruiting Singapore Eye Research Institute · Singapore · NCT06774651

• Effects of red light therapy on eye structures in myopic adults

  This study is testing different red light therapy techniques to see how they affect the eye structures of young adults with nearsightedness.

  Recruiting The Hong Kong Polytechnic University · Hong Kong · NCT06753773

• Study on the safety and rebound effect of SAT-001 for myopia in children

  This study is testing if a new software treatment for myopia can safely help children aged 5 to under 9 years old without causing problems once they stop using it.

  Recruiting at 3 sites S-Alpha Therapeutics, Inc. · Seoul, Choose One... and 4 other locations · NCT06742268

• Using low-level red light to control myopia in children

  This study is testing if low-level red light therapy can help slow down worsening eyesight in children aged 8-10 who have mild myopia.

  Recruiting Shanghai Eye Disease Prevention and Treatment Center · Shanghai, Shanghai Municipality · NCT06717048

• Testing low-dose atropine eye drops to slow down myopia in children

  This study is testing if low-dose atropine eye drops can help slow down worsening eyesight in children aged 6 to 12 who have myopia.

  Recruiting at 25 sites Phase 3 Oupushifang Pharmaceutical Technology Co., Ltd. · Hefei, Anhui and 24 other locations · NCT06708156

• Evaluating a deep learning model for selecting implantable collamer lenses using eye images

  This study is testing a new computer program that uses eye images to help doctors choose the best lens for people with nearsightedness.

  Recruiting Second Affiliated Hospital of Nanchang University · Nanchang, Jiangxi · NCT06669728

• Optimizing light exposure to prevent and control myopia in children

  This study tests if changing classroom lighting to mimic sunlight or using a smartphone app to guide light exposure can help prevent and control myopia in primary school children.

  Recruiting at 5 sites National University of Singapore · Singapore and 4 other locations · NCT06631339

• Optimizing light exposure to prevent and control myopia in children

  This study tests if changing classroom lighting to mimic sunlight or using a smartphone app to guide light exposure can help prevent and control myopia in primary school children.

  Recruiting at 5 sites National University of Singapore · Singapore and 4 other locations · NCT06631339

• Using artificial intelligence to improve cataract surgery outcomes for patients with high myopia

  This study is testing a new artificial intelligence tool to see if it can help improve cataract surgery results for patients with severe nearsightedness by providing better lens calculations.

  Recruiting Shanghai High Myopia Study Group · Shanghai, Shanghai Municipality · NCT06616506

• Wearing special contact lenses to slow nearsightedness in children

  This study is testing if special contact lenses can help slow down nearsightedness in children over the course of a year.

  Recruiting University of Alabama at Birmingham · Birmingham, Alabama · NCT06598423

• Combining atropine eye drops with defocus DIMS for controlling myopia in children

  This study is testing if using atropine eye drops together with special glasses can help children aged 6 to 12 with moderate to high myopia see better and slow down their eye growth.

  Recruiting Phase 1/2 Tianjin Medical University Eye Hospital · Tianjin, Tianjin Municipality · NCT06523504

• Evaluating Atropine for Delaying Myopia in Children

  This study is testing if a low-dose eye drop can help slow down worsening eyesight in children aged 3 to 12 who are becoming nearsighted.

  Recruiting Phase 3 Laboratorios Sophia S.A de C.V. · Mexico City · NCT06389110

• Using SAT-001 to treat myopia in children

  This study is testing if a new software treatment can help slow down worsening eyesight in children aged 5 to under 9 who have myopia.

  Recruiting S-Alpha Therapeutics, Inc. · Incheon · NCT06344572

• Evaluating Myopia Control Lenses for Children

  This study is testing if Bausch + Lomb Myopia Control Lenses can help children aged 8 to 12 with nearsightedness see better and slow down their vision worsening compared to another type of lens.

  Recruiting Bausch & Lomb Incorporated · Beijing, Beijing Municipality and 10 other locations · NCT06305663

• Comparing treatments for myopia in children

  This study is testing whether a special eye drop or special glasses can help slow down worsening eyesight in children aged 7 to 9 with myopia.

  Recruiting The Hong Kong Polytechnic University · Hong Kong · NCT06282848

• Comparing different methods for correcting myopia in youth

  This study tests which of three methods for correcting nearsightedness—special glasses, regular glasses, or contact lenses worn overnight—works best for kids aged 13 to 17 and how it affects their daily lives.

  Recruiting He Eye Hospital · Shenyang, Liaoning · NCT06278974

• Using QLM3004 to slow down myopia in children

  This study is testing if a new eye drop called QLM3004 can help slow down worsening eyesight in children aged 6 to 12 who have myopia.

  Recruiting Phase 3 Qilu Pharmaceutical Co., Ltd. · Wenzhou, Zhejiang · NCT06151587

• Evaluating Near Vision and Outdoor Time in Children with Myopia

  This study is trying to see if spending more time outdoors can help children with nearsightedness manage their vision better.

  Recruiting at 3 sites The University of New South Wales · Berkeley, California and 4 other locations · NCT06119243

• Comparing a new software for eye refraction with traditional methods

  This study is testing a new eye refraction software called Mobilerone to see if it gives accurate results for adults and older children with nearsightedness and astigmatism compared to traditional methods.

  Recruiting at 2 sites Beijing Airdoc Technology Co., Ltd. · Beijing, Beijing Municipality and 2 other locations · NCT06059521

• Comparing electronic spectacles and low dose atropine for myopia in children

  This study is testing whether electronic glasses or low-dose atropine can help slow down worsening eyesight in children aged 6 to 13.

  Recruiting Kubota Vision Inc. · Hsinchu · NCT06034379

• Controlling myopia in young children with a new type of glasses

  This study is testing a new type of glasses to see if they can help control the worsening of nearsightedness in children aged 6 to 8 years.

  Recruiting at 14 sites SightGlass Vision, Inc. · Oakland, California and 13 other locations · NCT06034327

• Effects of eye surgery on OCT measurements

  This study looks at how eye surgeries like Lasik affect the measurements taken by a special eye scan in people with nearsightedness who might be at risk for eye problems.

  Recruiting University of Nebraska · Omaha, Nebraska · NCT05856786

• China Axial Length Reference

  This project will measure axial length in 30,000 Chinese children aged 3 to 18 over three years to create age-specific reference ranges.

  Recruiting at 2 sites Shanghai Eye Disease Prevention and Treatment Center · Shanghai, Shanghai Municipality and 1 other locations · NCT05770661

• Using low-level red light therapy to control myopia in children

  This study is testing if low-level red light therapy can help control myopia in children aged 8-13 by comparing it to regular glasses over a year.

  Recruiting University of California, San Francisco · San Francisco, California · NCT05606237

• Contoura with Phorcides versus WaveLight Wavefront-Optimized LASIK for myopia with astigmatism

  This trial will test whether Contoura planned with Phorcides or WaveLight wavefront-optimized LASIK gives better vision and patient satisfaction for adults having LASIK for nearsightedness with astigmatism.

  Recruiting at 4 sites Vance Thompson Vision · Bozeman, Montana and 3 other locations · NCT05486546

• Effects of atropine eye drops on eye alignment and vision

  This study is testing if low doses of atropine eye drops can help children aged 5 to 14 with eye alignment issues and myopia see better and slow down their vision problems.

  Recruiting Eye & ENT Hospital of Fudan University · Shanghai · NCT05379855

• Using atropine eyedrops to treat myopia in children

  This study tests whether daily atropine eyedrops can help children with worsening nearsightedness see better.

  Recruiting Centre Hospitalier Universitaire de Saint Etienne · Saint-Etienne · NCT04252989

• Evaluating the effectiveness and safety of Paragon CRT® 100 Contact Lenses for myopia

  This study is testing if Paragon CRT® 100 Contact Lenses can safely help people with myopia see better over the long term.

  Recruiting at 4 sites CooperVision International Limited (CVIL) · Shanghai and 3 other locations · NCT04187599

• Using SMILE to correct high myopia

  This study is testing if a new eye surgery called SMILE can help people with very poor eyesight (high myopia) see better and recover quickly.

  Recruiting St. Franziskus Hospital · Münster, North Rhine-Westphalia · NCT04110067

• Using advanced eye imaging to assess conditions and effects of a medical food

  This study is testing how advanced eye imaging can help us understand eye conditions and see if a special medical food called Ocufolin can improve eye health over six months for both healthy people and those with eye issues.

  Recruiting University of Miami · Miami, Florida · NCT03135327

• Evaluating a new method for Implantable Collamer Lens implantation to treat high myopia

  This study is testing a new way to implant a special lens for people with severe nearsightedness to see if it’s safer and works better than the usual method.

  Recruiting Wenzhou Medical University · Guangzhou, Guangdong and 4 other locations · NCT03059043

• Diagnostic innovations for detecting glaucoma in eyes with and without myopia

  This project tests imaging and vision tests to see if they can better detect glaucoma or its worsening in adults with or without myopia.

  Recruiting University of California, San Diego · La Jolla, California · NCT00221897

NIH-funded research (40)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Sulfated molecules in the back of the eye and how they shape myopia progression

  This grant studies how losing certain building blocks in the eye’s outer layer may affect eye shape and the worsening of nearsightedness in pig eyes to model human disease.

  NIH research University of Mississippi · University, United States · NIH-11569095

• Understanding how myopia and glaucoma are connected through eye mechanics

  This study looks at how eye growth in myopia may influence glaucoma risk and what markers could identify it early.

  NIH research State College of Optometry · New York, United States · NIH-11418938

• Topical eyedrops to slow myopia progression in children

  A new eyedrop, IVMED-85, is being studied to help slow down myopia in kids by strengthening the eye’s tissues through a copper-related mechanism.

  NIH research Iveena Delivery Systems, INC. · Salt Lake City, United States · NIH-11402067

• Diagnostic Innovations in Glaucoma for High Myopia

  A study to improve early detection of open-angle glaucoma in people with high myopia using advanced eye imaging.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11397407

• PICNIC: Factors inside the eye linked to childhood near-sightedness

  Researchers are studying how eye structure and vision in young children may predict who will develop myopia, aiming to understand why some kids become nearsighted.

  NIH research New England College of Optometry · Boston, United States · NIH-11389764

• Peripheral vision factors behind kids’ nearsightedness

  A study with children explores how outer-edge eye signals and eye optics affect the worsening of nearsightedness and whether new lenses and tools can help slow or prevent it.

  NIH research University of Houston · Houston, United States · NIH-11374502

• Understanding why prematurity affects vision and how to prevent it

  Aims to understand how early eye development goes wrong in premature babies to prevent vision problems and nearsightedness.

  NIH research Oakland University · Rochester, United States · NIH-11365924

• How Visual Light Affects Eye Wiring in Nearsightedness

  This grant looks at how what we see and the light around us influence the brain signals that control myopia in people.

  NIH research Emory University · Atlanta, United States · NIH-11364913

• How eye focusing and multifocal lenses affect myopia in kids

  Researchers are studying how how an eye’s focusing and multifocal lenses work together to influence myopia progression in children.

  NIH research University of Rochester · Rochester, United States · NIH-11336325

• How nearsightedness may raise glaucoma risk in retinal cells and vessels

  A clinician-scientist is studying how myopia changes eye cells and blood vessels to understand why nearsighted people are more at risk for glaucoma.

  NIH research Research Foundation for the State University of New York, the · Albany, United States · NIH-11336318

• How a vitamin A–related molecule controls eye growth in myopia

  This project looks at whether a molecule called all-trans retinoic acid influences how the eye lengthens in people with myopia.

  NIH research Emory University · Atlanta, United States · NIH-11305986

• How light and close-up activities shape children's eyesight

  This project looks at whether lower bright light exposure and more close-up activities like reading or screens lead to nearsightedness in children and how the eye's tissues change.

  NIH research University of Houston · Houston, United States · NIH-11290775

• Strengthening the eye's outer layer to slow nearsightedness

  Looking at whether boosting natural strengthening of the eye's outer coat can slow worsening nearsightedness for people with progressive myopia.

  NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11285224

• Eye drops to strengthen the eye and slow childhood nearsightedness

  These experimental eye drops deliver copper to boost an enzyme and dopamine activity to help strengthen the eye and slow nearsightedness in children.

  NIH research Iveena Delivery Systems, INC. · Salt Lake City, United States · NIH-11261496

• How everyday sights and safer red light could slow nearsightedness

  This project looks at whether the kinds of images we see every day and a safer low-level red light approach can slow the eye growth that leads to nearsightedness, with the goal of helping children at risk of myopia.

  NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11249622

• Detecting glaucoma in people with high nearsightedness (high myopia)

  This project uses new three-dimensional eye imaging and analysis to find glaucoma earlier in people with high myopia.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11179185

• Cellular and structural changes in childhood nearsightedness

  Researchers are linking tiny cell and nerve changes with eye imaging to better understand why children develop worsening nearsightedness.

  NIH research Legacy Emanuel Hospital and Health Center · Portland, UNITED STATES · NIH-11178747

• How the eye grows and becomes nearsighted, seen cell by cell

  This work looks at individual eye cells in a primate model to learn why eyes grow too long and cause nearsightedness in children so future treatments can be improved.

  NIH research State College of Optometry · New York, United States · NIH-11178474

• Understanding Nearsightedness in Children

  This research aims to better understand how nearsightedness, or myopia, develops in children by looking at how their eyes and brains process vision.

  NIH research University of Houston · Houston, United States · NIH-11143652

• Globe-shaping changes during myopia treatment with full-eye OCT imaging

  This study tests a new full-eye imaging approach to see how the eye shape changes in kids and adults being treated for myopia with multifocal contact lenses.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-11133727

• Understanding Vision Problems in Premature Babies

  This project aims to understand why premature babies often develop vision problems and nearsightedness.

  NIH research Oakland University · Rochester, United States · NIH-11132886

• Understanding how multifocal contact lenses affect eye growth and myopia in children

  This study is looking at how multifocal contact lenses can help kids with blurry distance vision, known as myopia, by seeing if these lenses can improve their ability to focus and slow down the worsening of their eyesight.

  NIH research University of Rochester · Rochester, United States · NIH-11109524

• Understanding factors that lead to myopia in children

  This study is looking at how the quality of what kids see and how their brains process those images might affect the development of nearsightedness (myopia) in children, and it’s for young kids who are at different risks for myopia; over three years, we’ll check in with them every six months to learn more about their v

  NIH research New England College of Optometry · Boston, United States · NIH-11064165

• Investigating how light exposure and near work affect myopia development in children

  This study is looking into why kids and teens get nearsightedness, focusing on how things like not getting enough bright light and spending too much time on close-up activities might make it worse, so we can find better ways to help slow it down.

  NIH research University of Houston · Houston, United States · NIH-11050819

• Understanding how eye growth leads to myopia

  This study is looking into how a substance called all-trans retinoic acid affects eye growth in people with myopia, or nearsightedness, to help find better ways to stop or slow down the condition.

  NIH research Emory University · Atlanta, United States · NIH-11045080

• Understanding the causes of severe nearsightedness and its effects on the eyes

  This study is looking into how certain genes can cause severe nearsightedness and related eye problems, hoping to find new ways to help manage these conditions better for people who struggle with high myopia.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11030850

• Investigating how different visual environments affect myopia development

  This study is looking at how different visual surroundings can affect the growth of myopia (nearsightedness) in young eyes, using tree shrews to find out if certain scenes can help keep eyes healthy, and it’s also testing a new red light therapy that might slow down myopia progression.

  NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11021428

• How myopia affects eye cells and its link to glaucoma risk

  This study is looking at how being nearsighted might affect the cells and blood vessels in your eyes, which could increase the chance of getting glaucoma, and it's for anyone interested in understanding how myopia can lead to changes in eye health.

  NIH research State College of Optometry · New York, United States · NIH-11010024

• Understanding the changes in eye structure and function related to juvenile myopia

  This study is looking at how myopia (nearsightedness) affects the eyes of young patients by examining changes in eye cells and nerves, which could help us find better ways to treat this condition.

  NIH research Legacy Emanuel Hospital and Health Center · Portland, UNITED STATES · NIH-10952918

• Exploring ways to slow down myopia progression using animal models

  This study is looking at how to slow down myopia, or short-sightedness, by testing different medications in guinea pigs that have similar eyes to humans, to find better ways to help people with this condition.

  NIH research University of California Berkeley · Berkeley, United States · NIH-10952028

• A new method to control myopia in children using specific light wavelengths

  This study is looking at a new way to help kids with nearsightedness by using special red light to slow down how quickly their eyesight gets worse, and kids who join in will get to try out this light for a little bit each day.

  NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-10947633

• Understanding vision problems and myopia in premature infants

  This study is looking at how babies born early might develop vision problems, like nearsightedness, by examining the natural activity in their eyes that helps them grow properly, with the hope of finding ways to prevent or treat these issues.

  NIH research Oakland University · Rochester, United States · NIH-10923798

• Understanding how the eye grows and develops myopia at a cellular level

  This study is looking at how children's eyes grow and develop myopia (nearsightedness) to find out what causes these changes, with the hope of discovering better ways to prevent or treat myopia in kids.

  NIH research State College of Optometry · New York, United States · NIH-10913471

• Understanding how alcohol affects risky behaviors in young adults

  This study is looking at how drinking alcohol affects young adults' choices, like being aggressive or driving unsafely, by using smartphone tasks to see how alcohol changes their focus and decision-making in real life.

  NIH research University of Washington · Seattle, United States · NIH-10888687

• Exploring the link between myopia and glaucoma through cellular mechanisms

  This study is looking at how having myopia (nearsightedness) might raise the chances of getting glaucoma, a serious eye disease, and it aims to find ways to help protect your vision by tracking changes in your eyes over time.

  NIH research State College of Optometry · New York, United States · NIH-10872182

• Investigating how optical and neural factors contribute to nearsightedness in children

  This study is looking at how certain visual factors affect nearsightedness in kids, using special contact lenses and tools to see how different sights can change eye growth, with the hope of finding ways to help prevent or slow down myopia.

  NIH research University of Houston · Houston, United States · NIH-10863846

• Using eye growth data to enhance treatment for nearsightedness in children

  This study is looking at how to better treat nearsightedness in kids by understanding how their eyes grow, so doctors can predict who might develop myopia and find the best treatments for each child.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-10725732

• Investigating ways to delay the onset of nearsightedness in children

  This study is looking for ways to help kids aged 6 to 11 who might develop nearsightedness by testing if low concentration atropine eye drops can slow it down before it starts, which could help keep their eyes healthy as they grow up.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-10691555

• Understanding the factors that lead to myopia in children

  This study is looking at how the quality of what kids see and how their brains process those images might affect the development of nearsightedness (myopia) in children, and it’s for young kids who are at different risks for myopia, as researchers will check their vision and eye health every six months for three years

  NIH research New England College of Optometry · Boston, United States · NIH-10679002

• Eyedrops that help control nearsightedness by increasing collagen strength in the eye

  This study is testing a new eyedrop called IVMED-85 that could help kids with nearsightedness by making their eyes stronger, and it aims to see if this treatment is safe and effective for slowing down worsening vision.

  NIH research Iveena Delivery Systems, INC. · Salt Lake City, United States · NIH-10603432

Related topics

Quick answers

How many Myopia clinical trials are recruiting right now?

89, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 24 countries. The most sites are in China (36 trials), United States (21 trials), France (7 trials), Singapore (7 trials), Hong Kong (4 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 6, Phase 2: 3, Phase 4: 2, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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