Optimizing light exposure to prevent and control myopia in children

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the impact of daily light exposure on myopia prevention and control in primary school children. It features three arms: a technical intervention that modifies classroom lighting to mimic sunlight, a digital intervention that uses a smartphone app and light sensors to provide tailored recommendations, and a control group with standard lighting and no app access. The study aims to assess the effectiveness, safety, and feasibility of these interventions while also exploring their effects on sleep and cognitive performance.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Subject must meet all the inclusion criteria below to participate in this study.

  1. Written Informed Consent form from parent / legal guardian and assent from child subject has been obtained
  2. Is between 7 to 10 years of age at start of study intervention which is 2 January 2025 or 1 January 2026
  3. Studying in either Primary 2 or 3 classes of the participating school(s) in academic year 2025 or 2026.
  4. Presenting visual acuity or best corrected visual acuity (BCVA) better or equal to LogMAR 0.2 (equivalent to Snellen 6/9 or better) in each eye
  5. Normal Intraocular pressure (not more than 21mmHg)
  6. No ocular conditions (e.g., optic nerve disease, glaucoma, retinal diseases) except for refractive error.
  7. No ocular conditions affecting the accuracy of the ophthalmic examinations
  8. In good general health with no significant systemic diseases that may affect eye health

     Exclusion Criteria:
* All subjects meeting any of the exclusion criteria at baseline will be excluded from participation.

  1. Previous or ongoing myopia control treatment (including but not limited to orthokeratology, atropine, pirenzepine, myopia control spectacle and contact lenses, light therapy)
  2. Ongoing participation in other myopia prevention and control research trials
  3. Any systemic or neurologic diseases (e.g. cancer, epilepsy, Kawasaki disease) known to affect eye health or make the participant vulnerable to the ophthalmic examinations (e.g., light flash)
  4. Any other conditions precluding adherence to the protocol including unwillingness to refrain from myopia control treatment for the duration of the study

Where it's running

• National University of Singapore, Yong Loo Lin School of Medicine, Department of Ophthalmology, Eye N Brain Research Lab
  Singapore, Singapore Recruiting
• Marymount Convent School
  Singapore, Singapore Recruiting
• Bedok Green Primary School
  Singapore, Singapore Recruiting
• Westwood Primary School
  Singapore, Singapore Recruiting
• Wellington Primary School
  Singapore, Singapore Recruiting

Study contacts

• Principal investigator: Raymond P. Najjar, PhD — National University of Singapore
• Study coordinator: Raymond P. Najjar, PhD
• Email: lightspan@nus.edu.sg
• Phone: 006566018519

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.