NIH-funded research R01 grant

Understanding Nearsightedness in Children

Official title: Peripheral optical and neural contributions to myopia development

Funded at University of Houston · NIH-11143652 · Data updated 2026-11-12

This research aims to better understand how nearsightedness, or myopia, develops in children by looking at how their eyes and brains process vision.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Houston
NIH-funded
Lab location1 site (Houston, United States)
Project startSeptember 1, 2022
Project endJune 30, 2027
Funding year2025
Award (this year)$452,271
NIH project number5R01EY034151-04
Project IDNIH-11143652 on NIH RePORTER

Who could benefit from this research

Could help

This research is focused on understanding myopia in children, particularly those aged 0-11 years old who are developing or at risk of developing nearsightedness.

Less likely to help

Patients who are adults or whose myopia is already stable may not directly benefit from this specific research, which focuses on early development and progression.

What this research studies

Nearsightedness is a common vision problem that is becoming more widespread, especially in children, and severe cases can lead to serious eye diseases and even blindness. While some treatments exist, we don't fully understand why they work or what truly causes myopia to progress. This project will use new optical tools and custom contact lenses to explore how the outer parts of a child's vision and brain signals contribute to the eye's growth and nearsightedness. By uncovering these mechanisms, we hope to develop more effective ways to prevent or slow down myopia in children.

Why it matters

Potential benefit: If successful, this work could lead to new and more effective treatments or preventative measures for nearsightedness in children, potentially reducing the risk of severe vision problems later in life.

How similar studies have gone: While current interventions for myopia have shown some success, this research seeks to provide a clearer explanation for their mechanisms and explore new factors, building upon existing knowledge.

Where this research is happening

  • University of Houston
    Houston, United States
    Active

Researchers

  • Principal investigator: Yoon, Geunyoung — University of Houston
  • Study coordinator: Yoon, Geunyoung

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.