Exploring the link between myopia and glaucoma through cellular mechanisms
Official title: Myopia and Glaucoma, Linked via Mechanotransduction Mechanisms Affecting the Ganglion Cell Complex
Funded at State College of Optometry · NIH-10872182 · Data updated 2026-11-12
This study is looking at how having myopia (nearsightedness) might raise the chances of getting glaucoma, a serious eye disease, and it aims to find ways to help protect your vision by tracking changes in your eyes over time.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State College of Optometry NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $408,750 |
| NIH project number | 5R01EY034086-02 |
| Project ID | NIH-10872182 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with myopia, particularly those who may be at risk for developing glaucoma.
✕Less likely to help
Patients without myopia or those who do not have a family history of glaucoma may not benefit from this research.
What this research studies
This research investigates how myopia, a common vision condition, may increase the risk of developing glaucoma, a serious eye disease that can lead to blindness. The study focuses on understanding the mechanical processes that affect the ganglion cell complex in the eye, which is crucial for vision. By identifying genetic, cellular, and structural markers of glaucoma in patients with myopia, the research aims to develop new therapeutic strategies to protect eye health. Patients may be monitored over time to observe changes and gather data on the progression of these conditions.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools and treatments for patients at risk of glaucoma due to myopia.
How similar studies have gone: While the connection between myopia and glaucoma has been noted, this specific approach to understanding the mechanotransduction mechanisms is relatively novel and has not been extensively tested.
Where this research is happening
-
State College of Optometry
New York, United States Active
Researchers
- Principal investigator: Benavente-Perez, Alexandra — State College of Optometry
- Study coordinator: Benavente-Perez, Alexandra
Related research
Other NIH-funded projects on the same topics.
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Understanding how myopia and glaucoma are connected through eye mechanics
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Diagnostic Innovations in Glaucoma for High Myopia
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How nearsightedness may raise glaucoma risk in retinal cells and vessels
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Detecting glaucoma in people with high nearsightedness (high myopia)
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How myopia affects eye cells and its link to glaucoma risk
This study is looking at how being nearsighted might affect the cells and blood vessels in your eyes, which could increase the chance of getting glaucoma, and it's for anyone interested in understanding how myopia can lead to changes in eye health.
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IOP and CSF Pressure in Glaucoma Risk
This grant studies how eye pressure and cerebrospinal fluid pressure together influence glaucoma risk and vision loss.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.