Wearability and myopia control with ZEISS MyoCare versus ZEISS single‑vision spectacle lenses

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Children aged 7–13 with mild to moderate myopia are randomly assigned to wear one of three ZEISS spectacle lens types for six months. The protocol includes five in‑person clinic visits and two virtual follow‑ups to measure axial length, refractive error, and how well the lenses are worn. Eligible participants have cycloplegic spherical equivalent between −0.75 D and −5.00 D, astigmatism ≤1.50 D, anisometropia ≤1.50 D, and vision correctable to at least 0.8 in each eye. The trial is sponsored by ZEISS Vision Care and conducted at Hanoi Eye Hospital 2.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* be accompanied by a parent or guardian who is able to read and comprehend Vietnamese/English and sign a record of informed consent/assent;
* at baseline, be within the age range of 7 to 13 years old inclusive;
* be diagnosed as myopic having cycloplegic spherical equivalent between -0.75 dioptre (D) and -5.00 dioptre (D);
* astigmatism ≤1.50D;
* anisometropia of not more than 1.50D;
* be willing to comply with the wearing of clinical trial spectacles and clinical trial visit schedule as directed by the investigator;
* have ocular findings deemed to be normal;
* vision correctable to at least 0.8 or better in each eye with spectacles.

Exclusion Criteria:

* Any pre-existing systemic or ocular condition, including infection or disease that is likely to affect visual acuity and refractive error;
* Any systemic disease that adversely affects ocular health e.g. diabetes, Graves disease, and auto-immune diseases such as ankylosing spondylitis, multiple sclerosis, Sjögrens syndrome and systemic lupus erythematosus.
* Use of or a need for any systemic medication or topical medications which may alter normal ocular findings / are known to affect a participant's ocular health / physiology in an adverse or beneficial manner at enrolment and/or during the clinical trial. NB: Systemic antihistamines are allowed on an "as needed basis", provided they are not used prophylactically during the trial and at least 24 hours before the clinical trial product is used.
* History of eye trauma or eye surgery
* Amblyopia
* Anisometropia of not more than 1.50D
* Strabismus
* History of use of myopia control interventions such as Orthokeratology or atropine 3 months prior to commencement of this trial.
* Known allergy or intolerance to ingredients to cycloplegic eye-drops.
* Currently enrolled in another clinical trial.

Where it's running

• Hanoi Eye Hospital 2
  Hanoi, Vietnam Recruiting

Study contacts

• Principal investigator: Chi Hoang Viet Vu, MD — Hanoi Eye Hospital 2
• Study coordinator: Nicole Liu, MBBS, MOptom, PhD
• Email: xiao.liu@zeiss.com
• Phone: +61 413759820

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Evaluating a device for screening vision problems in young children

  This study is testing a new device to see if it can effectively find vision problems in children aged 3 to 8, whether they wear glasses or not.

  Recruiting Essilor International · Nancy, France and 1 other locations · NCT06882408

• Optimizing light exposure to prevent and control myopia in children

  This study tests if changing classroom lighting to mimic sunlight or using a smartphone app to guide light exposure can help prevent and control myopia in primary school children.

  Recruiting at 5 sites National University of Singapore · Singapore and 4 other locations · NCT06631339

• Hyperopic reserve screening for kindergartners in Beijing

  A population-wide screening tests whether senior kindergarten children in Beijing have enough hyperopic reserve to help prevent future myopia.

  Recruiting Beijing Tongren Hospital · Beijing · NCT07851532

• Do dual-focus multifocal contact lenses improve hand-eye coordination and sports vision compared with your usual lenses

  This study tests whether wearing dual-focus multifocal contact lenses improves hand-eye coordination and sports vision in adults who play baseball or softball and normally wear contact lenses.

  Recruiting Ohio State University · Columbus, Ohio · NCT07840209

• Two monthly silicone hydrogel multifocal toric contact lenses in wearers with astigmatism and myopia

  This study tests whether two popular soft multifocal toric contact lenses perform differently in adults who need vision correction for astigmatism and myopia.

  Recruiting CooperVision International Limited (CVIL) · New York, New York and 2 other locations · NCT07829419

• Seeing clearly in low light after Ray-Tracing guided LASIK

  A trial tests how well WaveLight Plus LASIK works for people with myopia and astigmatism and whether patients are satisfied after the procedure.

  Recruiting Phase 4 Vance Thompson Vision · Sioux Falls, South Dakota · NCT07790185

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.