NIH-funded research R01 grant

Globe-shaping changes during myopia treatment with full-eye OCT imaging

Official title: Changes in Globe Shape in Response to Myopia Treatment

Funded at Ohio State University · NIH-11133727 · Data updated 2026-11-12

This study tests a new full-eye imaging approach to see how the eye shape changes in kids and adults being treated for myopia with multifocal contact lenses.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionOhio State University
NIH-funded
Lab location1 site (Columbus, UNITED STATES)
Project startJuly 1, 2026
Project endDecember 31, 2030
Funding year2026
Award (this year)$747,274
NIH project number1R01EY036506-01A1
Project IDNIH-11133727 on NIH RePORTER

Who could benefit from this research

Could help

Children and adults starting or currently using multifocal soft contact lenses for myopia control who can undergo eye imaging.

Less likely to help

Participants without myopia or who cannot tolerate contact lens wear or eye imaging may not benefit.

What this research studies

We will use a novel pan-retinal OCT system to image the entire eye while people wear multifocal soft contact lenses, aiming to link eye shape changes to treatment effects on myopia. The project will recruit both pediatric and adult participants to map how peripheral and central eye regions respond to treatment over time. Results could help tailor lens designs and monitoring to slow myopia progression while keeping patients comfortable and safe.

Why it matters

Potential benefit: If successful, patients could benefit from more effective, personalized myopia control strategies and better imaging methods to monitor progress.

How similar studies have gone: Previous work supports the idea that peripheral retina and eye shape relate to myopia progression, but this full-eye OCT approach is a novel step.

Where this research is happening

  • Ohio State University
    Columbus, United States
    Active

Researchers

  • Principal investigator: Choi, Stacey S — Ohio State University
  • Study coordinator: Choi, Stacey S

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.