Comparing three methods for correcting myopia

Comparative Study of SMILE, ICL, and Wavelight Plus Alcon Technologies in Myopia Correction

Not applicable Interventional Beijing Visionly Plus Eye Hospital · NCT06788418

This study tests three different ways to correct nearsightedness to see which one works best and makes patients the happiest.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment1000 (estimated)
Ages18 Years to 40 Years
SexAll
SponsorBeijing Visionly Plus Eye Hospital Academic / other
Locations2 sites (Beijing and 1 other locations)
Trial IDNCT06788418 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the safety, efficacy, and patient satisfaction of three different techniques for correcting myopia: Small Incision Lenticule Extraction (SMILE), Implantable Collamer Lens (ICL), and the Wavelight Plus Alcon system. It aims to provide insights into how these methods compare in terms of outcomes for patients with myopia. Participants will be adults aged 18-40 with specific refractive error criteria, and the study will assess their experiences and results post-procedure.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18-40 with a spherical equivalent of -1.00 to -10.00 D and stable refraction for at least 12 months.

Not a fit: Patients with other ocular pathologies, previous refractive surgery, pregnancy or nursing, or autoimmune disorders may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could help identify the most effective and satisfactory method for myopia correction, improving vision outcomes for patients.

How similar studies have performed: Other studies have shown success with similar refractive surgery techniques, but the comparison of these specific methods is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults aged 18-40 years
* Spherical equivalent of -1.00 to -10.00 D
* Stable refraction for at least 12 months
* Informed consent provided

Exclusion Criteria:

* Other ocular pathologies
* Previous refractive surgery
* Pregnancy or nursing
* Autoimmune or connective tissue disorders

Where this trial is running

Beijing and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions MyopiamyopiaSmall Incision Lenticule ExtractionImplantable Collamer LensWavelight Plus Alcon systemvision
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.