Clinical trial Recruiting at 2 sites Interventional Ages 18 to 40

Comparing three methods for correcting myopia

Official title: Comparative Study of SMILE, ICL, and Wavelight Plus Alcon Technologies in Myopia Correction

Run by Beijing Visionly Plus Eye Hospital · NCT06788418 · Data updated 2026-11-12

This study tests three different ways to correct nearsightedness to see which one works best and makes patients the happiest.

Quick facts

Study typeInterventional
Ages18 Years to 40 Years
SexAll
Enrollment1000 (estimated)
SponsorBeijing Visionly Plus Eye Hospital
Academic / other
Locations2 sites (Beijing and 1 other locations)
StatusRecruiting
StartedJanuary 20, 2025
Main results expectedDecember 31, 2025
Study endsDecember 31, 2025
Registry record updatedJanuary 23, 2025
Trial IDNCT06788418 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 18-40 with a spherical equivalent of -1.00 to -10.00 D and stable refraction for at least 12 months.

Probably not a fit

Patients with other ocular pathologies, previous refractive surgery, pregnancy or nursing, or autoimmune disorders may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the safety, efficacy, and patient satisfaction of three different techniques for correcting myopia: Small Incision Lenticule Extraction (SMILE), Implantable Collamer Lens (ICL), and the Wavelight Plus Alcon system. It aims to provide insights into how these methods compare in terms of outcomes for patients with myopia. Participants will be adults aged 18-40 with specific refractive error criteria, and the study will assess their experiences and results post-procedure.

Why it matters

Potential benefit: If successful, this study could help identify the most effective and satisfactory method for myopia correction, improving vision outcomes for patients.

How similar studies have gone: Other studies have shown success with similar refractive surgery techniques, but the comparison of these specific methods is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults aged 18-40 years
* Spherical equivalent of -1.00 to -10.00 D
* Stable refraction for at least 12 months
* Informed consent provided

Exclusion Criteria:

* Other ocular pathologies
* Previous refractive surgery
* Pregnancy or nursing
* Autoimmune or connective tissue disorders

Where it's running

  • Beijing New Vision Eye Hospital
    Beijing, China
    Recruiting
  • Beijing Visionly Plus Eye Hospital
    Beijing, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.