How everyday sights and safer red light could slow nearsightedness

Myopia and the Visual Environment

NIH-funded research University of Alabama at Birmingham · NIH-11249622

This project looks at whether the kinds of images we see every day and a safer low-level red light approach can slow the eye growth that leads to nearsightedness, with the goal of helping children at risk of myopia.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Alabama at Birmingham NIH-funded
Lab location1 site (Birmingham, United States)
Project IDNIH-11249622 on NIH RePORTER

What this research studies

Researchers will use a novel experimental technique in tree shrews, a small diurnal mammal similar to primates, to model how the developing eye responds to different visual scenes. The team will first compare a range of real-world visual environments to see which image patterns help prevent excessive eye elongation. They will then work to develop an improved Repeated Low-level Red Light (RLRL) therapy that aims to keep anti-myopia effects while meeting established safety limits. Results are intended to guide future human-safe treatments and environment-based recommendations to reduce myopia risk.

Who could benefit from this research

Good fit: Children and teenagers who are developing or at high risk of progressive myopia would be the main group likely to benefit from treatments informed by this research.

Not a fit: People with long-standing, stable high myopia or eye conditions unrelated to axial elongation are unlikely to receive direct benefit from these approaches.

Why it matters

Potential benefit: If successful, the work could lead to safer light-based treatments and practical visual-environment guidance that slow eye growth and lower the number of people who become myopic.

How similar studies have performed: Early reports of red-light therapies have shown strong anti-myopia effects but raised safety concerns, while testing the role of everyday visual scenes is a more novel approach with limited prior clinical data.

Where this research is happening

Birmingham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.