Effects of red light therapy on eye structures in myopic adults

The Short-term Impact of Different Types of Red Light Therapy on Choroid and Retina

This study is testing different red light therapy techniques to see how they affect the eye structures of young adults with nearsightedness.

Quick facts

• Phase: NA
• Study type: Interventional
• Enrollment: 60 (estimated)
• Ages: 18 Years to 40 Years
• Sex: All
• Sponsor: The Hong Kong Polytechnic University (other)
• Locations: 1 site (Hong Kong)
• Trial ID: NCT06753773 on ClinicalTrials.gov

What this trial studies

This research project is a randomized controlled trial that investigates the short-term effects of different red light therapy techniques on the choroidal and retinal structures in adults with myopia. The study will enroll 45 participants aged 18 to 40, who will be assigned to one of three groups based on the size and shape of the light spots used during therapy. The primary goal is to identify which retinal regions are most affected by low-level red light therapy, while also assessing the safety of these interventions. Participants will undergo repeated treatments to evaluate potential choroidal thickening.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 to 40 with myopia between -1.00D and -6.00D and a best corrected visual acuity of 20/20 or better.

Not a fit: Patients with significant ocular or systemic diseases, or those who have undergone similar therapies recently, may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to new therapeutic options for managing myopia and improving eye health.

How similar studies have performed: While the specific application of red light therapy for myopia is relatively novel, similar approaches in other ocular conditions have shown promising results.

Eligibility criteria

Inclusion Criteria:

1. Age: 18 to 40 years.
2. Myopic spherical equivalent refraction (SER) between -1.00D to -6.00D in both eyes.
3. Best corrected visual acuity (BCVA): 20/20 or greater.
4. Informed consent for participation.

Exclusion Criteria:

1. Anisometropia greater than 1.50D.
2. Ophthalmic diseases other than refractive errors, including but not limited to strabismus and binocular vision abnormalities in either eye.
3. Systemic diseases (e.g., endocrine, cardiac diseases) and developmental abnormalities.
4. Inability to attend regular follow up assessment.
5. Undergo RLRL therapy in the past 6 months
6. Contraindications to RLRL therapy.

Where this trial is running

Hong Kong

• The Hong Kong Polytechnic University — Hong Kong, Hong Kong (RECRUITING)

Study contacts

• Study coordinator: Mingguang He

Conditions: Myopia, myopia, red light therapy, choroidal, retinal