Using artificial intelligence to improve cataract surgery outcomes for patients with high myopia

Artificial Intelligence for Highly Myopic Cataract

Shanghai High Myopia Study Group · NCT06616506

This study is testing a new artificial intelligence tool to see if it can help improve cataract surgery results for patients with severe nearsightedness by providing better lens calculations.

Quick facts

Study typeObservational
Enrollment500000 (estimated)
SexAll
SponsorShanghai High Myopia Study Group (other)
Locations1 site (Shanghai, Shanghai Municipality)
Trial IDNCT06616506 on ClinicalTrials.gov

What this trial studies

This observational study aims to develop a multi-center artificial intelligence model to enhance the accuracy of intraocular lens calculations for patients suffering from highly myopic cataracts. The research focuses on addressing the limitations of existing lens calculation formulas, which are primarily based on data from European and American populations, by utilizing data from the Asian population where high myopia is prevalent. By improving the predictive accuracy of postoperative diopter outcomes, the study seeks to reduce the risk of blindness associated with high myopia cataracts. The AI model will analyze various biometric indicators to provide more precise calculations tailored to this specific patient group.

Who should consider this trial

Good fit: Ideal candidates for this study are patients with high myopia (axial length ≥ 26 mm) who also have cataracts and are seeking surgical treatment.

Not a fit: Patients who are unable to undergo the required examinations or cooperate with the study protocols may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could significantly improve surgical outcomes and reduce the risk of complications for patients with highly myopic cataracts.

How similar studies have performed: While the use of artificial intelligence in medical applications is growing, this specific approach to improving intraocular lens calculations for highly myopic cataracts is relatively novel and has not been extensively tested in prior studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Axial length ≥ 26 mm and patients with high myopia complicated by cataracts who visit our hospital.

Preoperative anterior segment photography and cataract severity assessment, along with fundus OCT examination, have been performed.

If surgical treatment is conducted, the postoperative follow-up period should be no less than 1 month.

There are no missing clinical data before and after the surgery.

Exclusion Criteria:

Patients who are unable to cooperate with the required examinations for this study.

Where this trial is running

Shanghai, Shanghai Municipality

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Cataract, High Myopia, Myopia, Automatic Judgement, Risk Reduction, Diagnoses Disease, highly myopic cataract, artificial intelligence

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.