Clinical trial Recruiting at 2 sites Observational Ages 3 to 18

China Axial Length Reference

Official title: China Nine Provinces Children Eye Study

Run by Shanghai Eye Disease Prevention and Treatment Center · NCT05770661 · Data updated 2026-11-12

This project will measure axial length in 30,000 Chinese children aged 3 to 18 over three years to create age-specific reference ranges.

Quick facts

Study typeObservational
Ages3 Years to 18 Years
SexAll
Enrollment30000 (estimated)
SponsorShanghai Eye Disease Prevention and Treatment Center
Academic / other
Locations2 sites (Shanghai, Shanghai Municipality and 1 other locations)
StatusRecruiting
StartedMarch 10, 2023
Main results expectedDecember 31, 2026
Study endsDecember 31, 2026
Registry record updatedAugust 7, 2026
Trial IDNCT05770661 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are children aged 3 to 18 who have lived in the study area for at least one year, can cooperate with eye exams, and whose parents or guardians provide consent.

Probably not a fit

Children with significant mental or ophthalmic diseases that prevent reliable eye assessment, those unable to cooperate, or those planning to move away within two years are unlikely to benefit from participation.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a multicenter, observational cohort of 30,000 children and adolescents in China with baseline cycloplegic eye measurements and annual visits for three years. Investigators will collect axial length and related ocular parameters to map growth trajectories by age. Participants are recruited from several hospitals and must have lived in the study area for at least one year and remain locally available for two more years. The main goal is to produce normative axial length reference ranges to inform clinical care and public health approaches to myopia in Chinese youth.

Why it matters

Potential benefit: If successful, clinicians and public health programs will have robust, age-specific axial length norms to better predict myopia risk and guide monitoring or interventions for Chinese children.

How similar studies have gone: Previous population-based axial length and myopia growth studies have informed care, but this large multicenter, three-year Chinese cohort is comparatively larger and more regionally focused.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Aged 3 to 18 years
* Have been lived in the research areas for at least one year, and will not move to other places in the following two years
* Parents or guardians sign an informed consent form, and children over 6 years old need oral consent to participate

Exclusion Criteria:

* Mental diseases, unable to cooperate to complete the eye assessment
* Ophthalmic diseases, inability to cooperate to complete the inspection

Where it's running

  • Shanghai Eye Disease Prevention & Treatment Center
    Shanghai, Shanghai Municipality, China
    Recruiting
  • Shanghai Eye Disease Prevention and Treatment Center
    Shanghai, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.