How nearsightedness may raise glaucoma risk in retinal cells and vessels
Official title: The Effect of Myopia on Retinal Ganglion Cells, Astrocytes and Vasculature, and its Relationsip to Glaucoma Susceptibility
Funded at Research Foundation for the State University of New York, the · NIH-11336318 · Data updated 2026-11-12
A clinician-scientist is studying how myopia changes eye cells and blood vessels to understand why nearsighted people are more at risk for glaucoma.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Research Foundation for the State University of New York, the NIH-funded |
| Lab location | 1 site (Albany, United States) |
| Project start | February 1, 2024 |
| Project end | January 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $161,624 |
| NIH project number | 5K08EY034545-03 |
| Project ID | NIH-11336318 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are individuals with myopia and early signs or risk factors for glaucoma who may benefit from future targeted interventions.
✕Less likely to help
People without myopia or glaucoma risk factors may have limited direct benefit from these findings.
What this research studies
Over four years, the researcher will combine clinical insight with cellular and electrophysiology techniques to explore how myopia affects retinal ganglion cells, astrocytes, and blood vessels and how these changes relate to glaucoma susceptibility. The program emphasizes translational training, mentorship, and independent research development in the field of myopic eye disease and glaucoma. The project leverages protected research time and aims to build skills that will help the trainee become an independent investigator focused on preventing vision loss in myopic patients.
Why it matters
Potential benefit: If successful, this work could illuminate new mechanisms linking myopia to glaucoma risk and guide strategies to protect vision in people with myopia.
How similar studies have gone: Previous research has established links between myopia and glaucoma risk, and this program seeks to deepen mechanistic understanding with translational approaches.
Where this research is happening
-
Research Foundation for the State University of New York, the
Albany, United States Active
Researchers
- Principal investigator: Lin, Carol — Research Foundation for the State University of New York, the
- Study coordinator: Lin, Carol
Related research
Other NIH-funded projects on the same topics.
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Understanding how myopia and glaucoma are connected through eye mechanics
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Diagnostic Innovations in Glaucoma for High Myopia
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Detecting glaucoma in people with high nearsightedness (high myopia)
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-
How myopia affects eye cells and its link to glaucoma risk
This study is looking at how being nearsighted might affect the cells and blood vessels in your eyes, which could increase the chance of getting glaucoma, and it's for anyone interested in understanding how myopia can lead to changes in eye health.
-
Exploring the link between myopia and glaucoma through cellular mechanisms
This study is looking at how having myopia (nearsightedness) might raise the chances of getting glaucoma, a serious eye disease, and it aims to find ways to help protect your vision by tracking changes in your eyes over time.
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IOP and CSF Pressure in Glaucoma Risk
This grant studies how eye pressure and cerebrospinal fluid pressure together influence glaucoma risk and vision loss.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.