Effects of eye surgery on OCT measurements
To Study the Effects of Refractive Surgery on Optical Coherence Tomography (OCT) Measurements in the Eye: A Pilot Study
This study looks at how eye surgeries like Lasik affect the measurements taken by a special eye scan in people with nearsightedness who might be at risk for eye problems.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 33 (estimated) |
| Ages | 19 Years and up |
| Sex | All |
| Sponsor | University of Nebraska Academic / other |
| Locations | 1 site (Omaha, Nebraska) |
| Trial ID | NCT05856786 on ClinicalTrials.gov |
What this trial studies
This observational study investigates how refractive surgeries, such as Lasik, impact optical coherence tomography (OCT) measurements in the eye. It focuses on patients with myopia who are at risk of developing conditions like myopic maculopathy or glaucoma, which require OCT monitoring. The study aims to understand the potential changes in OCT parameters following refractive surgery, as previous research has shown mixed results regarding the effects of altered refractive status on OCT outcomes. By analyzing these changes, the study seeks to provide insights into the reliability of OCT measurements post-surgery.
Who should consider this trial
Good fit: Ideal candidates are patients undergoing refractive surgery for myopia.
Not a fit: Patients with significant astigmatism, poor visual acuity, unstable fixation, or severe dry eye may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the accuracy of OCT monitoring in patients who have undergone refractive surgery.
How similar studies have performed: While some studies have simulated the effects of refractive surgery on OCT measurements, the results have been inconsistent, indicating that this area is still under-explored.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patients undergoing refractive surgery 2. For patients undergoing bilateral eye surgery, the one with higher degree of ametropia will be included. Exclusion Criteria: 1. Astigmatism more than 3 Diopters 2. Visual acuity worse than 20/25 3. Patients with unstable visual fixation 4. Severe Dry Eye
Where this trial is running
Omaha, Nebraska
- Unversity of Nebraska Medical Center — Omaha, Nebraska, United States (Recruiting)
Study contacts
- Principal investigator: Pukhraj P Rishi, MBBS — University of Nebraska
- Study coordinator: Pukhraj P Rishi, MBBS
- Email: pukhraj.rishi@unmc.edu
- Phone: 402-559-2020
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.