Condition

Presbyopia clinical trials and research

• 16Clinical trials
• 2NIH research projects
• 2New in 30 days
• 11Countries

Newest Presbyopia clinical trials

All recruiting trials (16)

• See if the Morrow eProgressive lenses work better than standard PALs for presbyopia

  This study tests whether the electronically adjustable Morrow eProgressive lenses help people with presbyopia see and move more naturally compared with traditional progressive lenses.

  Recruiting Morrow Eyewear · Antwerp and 2 other locations · NCT07878416

• Volumetric visual fields with occupational vs general-purpose progressive lenses in presbyopia

  This study tests whether two occupational progressive lenses and a general-purpose PAL give different depth of clear vision at multiple distances for people with presbyopia.

  Recruiting University of Seville · Seville, Andalusia · NCT07870785

• Trying DAILIES TOTAL1 Multifocal Lenses in satisfied INFUSE wearers

  This study tests whether switching satisfied INFUSE One-Day Multifocal wearers to DAILIES TOTAL1 Multifocal lenses maintains comfort and clear vision.

  Recruiting Gordon Schanzlin New Vision · La Jolla, California · NCT07638943

• VisAbility Micro Insert System for Presbyopia

  A new device called the VisAbility Micro Insert System is being tested to see if it can improve near vision at reading distance for adults with presbyopia.

  Recruiting at 2 sites VisDura, Inc. · Bochum and 1 other locations · NCT07637500

• Volumetric visual fields with progressive lenses for presbyopia at intermediate and near distances

  Researchers will test two occupational progressive lenses to see which provides a larger clear field at intermediate and near distances for people with presbyopia.

  Recruiting University of Seville · Seville, Andalusia and 1 other locations · NCT07617090

• Total30 Multifocal Toric Contact Lenses in Presbyopic Toric Wearers

  This study tests whether Total30 MFT toric contact lenses are comfortable and acceptable for people who already wear reusable toric lenses and are now presbyopic.

  Recruiting Southern College of Optometry · Memphis, Tennessee · NCT07586982

• A Smart Aperture Lens to Help Keratoconus and Presbyopia

  This study tests the NOA lens, a custom scleral contact lens with a central aperture, to see if it improves vision for people with keratoconus and presbyopia.

  Recruiting at 2 sites Azalea Vision · Antwerp and 1 other locations · NCT07559188

• LBV vs traditional monovision LASIK for presbyopia

  In adults 40–55 with presbyopia, this study tests whether laser blended vision (LBV) provides better vision at distance, intermediate, and near after LASIK than traditional monovision LASIK.

  Recruiting Zhongshan Ophthalmic Center, Sun Yat-sen University · Guangzhou, Guangdong · NCT07512089

• My Eyes, My Light — community eye screening in Char Fasson

  This project tests whether a community-based screening program can find treatable eye problems in people aged 35 and older who live in Char Fasson, Bangladesh.

  Recruiting Data Yakka, Inc. · Char Fasson, Bhola · NCT07135570

• Qlosi eye drops to improve daily life for people with presbyopia

  This trial will test whether Qlosi 0.4% eye drops, used twice daily, can improve quality of life for people aged 45–64 who have presbyopia and need near vision help.

  Recruiting at 2 sites Phase 4 Southern College of Optometry · Medina, Minnesota and 1 other locations · NCT07113210

• How EDOF lens implants change eye light sensitivity after presbyopic correction

  This will test whether people aged 45–75 who had EDOF intraocular lens implants need different lighting levels to reach their best vision.

  Recruiting Democritus University of Thrace · Alexandroupoli, Evros · NCT07077967

• Evaluating eye drops for treating presbyopia in Chinese patients

  This study is testing two different eye drops to see if they can help Chinese patients with presbyopia see better.

  Recruiting Phase 2 Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd. · Wenzhou, Zhejiang · NCT06948357

• Improving near vision for presbyopia using the VIS Opti-K System

  This study is testing a new laser treatment to see if it can improve near vision for people with presbyopia who have mild vision issues.

  Recruiting at 4 sites Phase 3 VIS, Inc. · Boca Raton, Florida and 3 other locations · NCT06487897

• Safety assessment of the IC-8 Apthera IOL after cataract treatment

  This study is testing the safety of the IC-8 Apthera eye lens in people who have had cataract surgery and need treatment for a common complication called posterior capsule opacification.

  Recruiting at 14 sites Bausch & Lomb Incorporated · Dothan, Alabama and 13 other locations · NCT06060041

• IOL with a Virtual Aperture for clearer near and distance vision after cataract surgery

  A device study tests whether a virtual aperture intraocular lens can help adults with cataracts see clearly at distances and near without glasses.

  Recruiting at 7 sites Z Optics, Inc. · Coimbra and 7 other locations · NCT05955846

• Using advanced eye imaging to assess conditions and effects of a medical food

  This study is testing how advanced eye imaging can help us understand eye conditions and see if a special medical food called Ocufolin can improve eye health over six months for both healthy people and those with eye issues.

  Recruiting University of Miami · Miami, Florida · NCT03135327

NIH-funded research (2)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Investigating lens mechanics in aging eyes to improve vision

  This study is looking at how the eye's lens changes as we get older, especially for people who have trouble seeing things up close, and it uses special imaging tools to better understand these changes so we can find new ways to help improve vision.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11299264

• Investigating lens mechanics in aging eyes to improve vision

  This study is looking at how the eye's lens changes as we get older, especially for people who have trouble seeing things up close, and it hopes to find new ways to help improve vision for those affected by this common issue.

  NIH research Univ of Maryland, College Park · College Park, United States · NIH-11036250

Related topics

Quick answers

How many Presbyopia clinical trials are recruiting right now?

16, as of November 12, 2026. 2 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 11 countries. The most sites are in United States (6 trials), Spain (3 trials), Belgium (2 trials), China (2 trials), Germany (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 1, Phase 2: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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