Understanding how the eye grows and develops myopia at a cellular level
Official title: Molecular Mechanisms of Emmetropization and Experimental Myopia at Single Cell Resolution
Funded at State College of Optometry · NIH-10913471 · Data updated 2026-11-12
This study is looking at how children's eyes grow and develop myopia (nearsightedness) to find out what causes these changes, with the hope of discovering better ways to prevent or treat myopia in kids.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State College of Optometry NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 30, 2022 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $580,561 |
| NIH project number | 5R01EY033824-03 |
| Project ID | NIH-10913471 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children aged 0-11 years who are at risk of developing myopia or are already experiencing myopia.
✕Less likely to help
Patients who are older than 11 years or those with established severe myopia may not benefit from this research.
What this research studies
This research investigates the complex biological processes that control eye growth and the development of myopia, particularly in children. By using advanced animal models, the study aims to uncover the cellular and molecular mechanisms involved in emmetropization, the process by which the eye adjusts its shape for clear vision. Researchers will analyze how genetic and environmental factors interact to influence eye development, which could lead to better treatments for myopia. The findings may provide insights into preventing vision-threatening conditions associated with myopia.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing and managing myopia in children, reducing the risk of serious eye conditions later in life.
How similar studies have gone: Previous research has shown promising results in understanding myopia through animal models, but this specific approach focusing on cellular mechanisms is relatively novel.
Where this research is happening
-
State College of Optometry
New York, United States Active
Researchers
- Principal investigator: Troilo, David B — State College of Optometry
- Study coordinator: Troilo, David B
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.