Condition

Astigmatism clinical trials and research

• 22Clinical trials
• 9Countries

Newest Astigmatism clinical trials

All recruiting trials (22)

• Two monthly silicone hydrogel multifocal toric contact lenses in wearers with astigmatism and myopia

  This study tests whether two popular soft multifocal toric contact lenses perform differently in adults who need vision correction for astigmatism and myopia.

  Recruiting CooperVision International Limited (CVIL) · New York, New York and 2 other locations · NCT07829419

• Seeing clearly in low light after Ray-Tracing guided LASIK

  A trial tests how well WaveLight Plus LASIK works for people with myopia and astigmatism and whether patients are satisfied after the procedure.

  Recruiting Phase 4 Vance Thompson Vision · Sioux Falls, South Dakota · NCT07790185

• Orthokeratology contact lenses with a 5 mm optic zone diameter

  This study tests Paragon CRT lenses with a 5 mm optic zone in kids and young adults to see how well they fit, how well they vision, and how comfortable they are at night.

  Recruiting at 2 sites CooperVision International Limited (CVIL) · Pleasanton, California and 2 other locations · NCT07751172

• Corneal Biomechanics and Surgical Astigmatism after Cataract Surgery in Pseudoexfoliation

  This study tests how the cornea's biomechanical properties before cataract surgery relate to the amount of blinking surgically induced astigmatism, comparing people with pseudoexfoliation to those without.

  Recruiting Eye Clinic Medic Zuljan Jukic · Split, Splitsko-dalmatinska County · NCT07722247

• SMILE in one eye vs Ray tracing-guided LASIK in the fellow eye

  This study tests two laser vision correction methods—SMILE in one eye and ray-tracing guided LASIK in the other eye—to see which provides better vision and quality of life for adults with myopia and astigmatism.

  Recruiting Phase 4 Stanford University · Palo Alto, California · NCT07721714

• Nomogram for Astigmatism Correction of KLEx

  This study tests whether using a nomogram can improve outcomes after astigmatism correction in adults who meet certain eye health criteria.

  Recruiting Tianjin Eye Hospital · Tianjin, Tianjin Municipality · NCT07605221

• Clareon TruPlus IOLs in Bilateral Cataract Surgery

  This study tests Clareon TruPlus Monofocal IOLs to see how safe they are and how well they perform for people with both eyes affected by cataracts.

  Recruiting at 5 sites Alcon Research · Phoenix, Arizona and 4 other locations · NCT07502456

• Daily disposable toric contact lenses for long-day wear.

  This will test whether daily disposable toric contact lenses stay comfortable and provide clear vision for people with astigmatism who wear lenses for long days.

  Recruiting Ohio State University · Columbus, Ohio · NCT07303920

• Using asymmetrical toric intraocular lenses to improve vision for people with irregular corneas

  This will test a custom asymmetrical toric intraocular lens during cataract surgery to reduce irregular astigmatism and improve vision in adults with irregular corneas.

  Recruiting Johannes Kepler University of Linz · Linz · NCT07294716

• Comparing two trifocal toric intraocular lenses for cataract surgery.

  This trial will test two different trifocal toric intraocular lenses to see which gives better intermediate-distance vision and satisfaction for adults with cataracts and regular corneal astigmatism.

  Recruiting at 5 sites Biotech Healthcare Holding Gmbh · Düsseldorf, North Rhine-Westphalia and 5 other locations · NCT07232615

• Comparing Ray‑Tracing Guided LASIK with three other laser vision correction methods for myopia and astigmatism

  This test will compare Ray‑Tracing Guided LASIK to three other laser or lenticule refractive procedures for adults with moderate myopia, with or without astigmatism.

  Recruiting Hoopes Vision · Draper, Utah · NCT07201298

• Femtosecond arcuate corneal incisions combined with a Light Adjustable Lens for correcting astigmatism during lens surgery

  This will try whether precise femtosecond arcuate corneal incisions plus a Light Adjustable Lens can reduce astigmatism and improve vision for adults having cataract or refractive lens exchange.

  Recruiting at 2 sites Phase 4 Center For Sight · Venice, Florida and 1 other locations · NCT07140653

• WaveLight Plus LASIK for nearsightedness and astigmatism

  This study will try WaveLight Plus LASIK in adults with nearsightedness and astigmatism to see if it improves vision, satisfaction, and quality of life over three months.

  Recruiting Laser Defined Vision · Greensboro, North Carolina · NCT07127757

• Wavefront-guided LASIK versus ray-tracing-guided LASIK in opposite eyes

  We will try wavefront-guided LASIK in one eye and ray-tracing-guided LASIK in the other eye of adults 22 and older with nearsightedness (with up to 3 diopters of astigmatism) to see if one gives better vision outcomes.

  Recruiting Stanford University · Palo Alto, California · NCT07078799

• Algorithm-guided eye refraction for children aged 6–12

  This project tests whether an algorithm-guided subjective refraction program (two versions) can give accurate non-cycloplegic eyeglass prescriptions for children 6–12 compared with the usual manual subjective refraction.

  Recruiting Essilor International · Vila Nova de Famalicão · NCT07046065

• Evaluating a device for screening vision problems in young children

  This study is testing a new device to see if it can effectively find vision problems in children aged 3 to 8, whether they wear glasses or not.

  Recruiting Essilor International · Nancy, France and 1 other locations · NCT06882408

• Using laser treatment to accurately mark astigmatism direction

  This study is testing a new laser treatment to see if it can help improve the accuracy of correcting astigmatism during eye surgery.

  Recruiting Tianjin Eye Hospital · Tianjin, Tianjin Municipality · NCT06694051

• Comparing a new software for eye refraction with traditional methods

  This study is testing a new eye refraction software called Mobilerone to see if it gives accurate results for adults and older children with nearsightedness and astigmatism compared to traditional methods.

  Recruiting at 2 sites Beijing Airdoc Technology Co., Ltd. · Beijing, Beijing Municipality and 2 other locations · NCT06059521

• Contoura with Phorcides versus WaveLight Wavefront-Optimized LASIK for myopia with astigmatism

  This trial will test whether Contoura planned with Phorcides or WaveLight wavefront-optimized LASIK gives better vision and patient satisfaction for adults having LASIK for nearsightedness with astigmatism.

  Recruiting at 4 sites Vance Thompson Vision · Bozeman, Montana and 3 other locations · NCT05486546

• Evaluation of different intraocular lenses for cataract surgery

  This study is testing different types of lenses used in cataract surgery to see which one helps people with astigmatism see better after their operation.

  Recruiting Medical University of Vienna · Vienna, State of Vienna · NCT03803852

• Analyzing corneal astigmatism measurements in different regions

  This study is testing how different ways of measuring corneal astigmatism can help improve accuracy for patients who have had cataract surgery.

  Recruiting Wenzhou Medical University · Wenzhou, Zhejiang · NCT03299530

• Evaluation of vision quality after LASIK, SMILE, and PRK surgery in physicians

  This study is testing how LASIK, SMILE, and PRK eye surgeries affect the vision quality and overall life satisfaction of doctors.

  Recruiting Stanford University · Palo Alto, California · NCT02576483

Related topics

Quick answers

How many Astigmatism clinical trials are recruiting right now?

22, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 9 countries. The most sites are in United States (12 trials), China (4 trials), Spain (2 trials), Austria (2 trials), Germany (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 3. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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