Understanding the changes in eye structure and function related to juvenile myopia
Official title: Novel correlations in cellular, molecular and structural alterations in experimental juvenile myopia
Funded at Legacy Emanuel Hospital and Health Center · NIH-10952918 · Data updated 2026-11-12
This study is looking at how myopia (nearsightedness) affects the eyes of young patients by examining changes in eye cells and nerves, which could help us find better ways to treat this condition.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Legacy Emanuel Hospital and Health Center NIH-funded |
| Lab location | 1 site (Portland, UNITED STATES) |
| Project start | September 1, 2024 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $210,534 |
| NIH project number | 1R21EY036560-01 |
| Project ID | NIH-10952918 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adolescents experiencing myopia or those at risk of developing it.
✕Less likely to help
Patients with stable vision or those who have already undergone corrective procedures for myopia may not benefit from this research.
What this research studies
This research investigates the cellular and molecular changes that occur in the eyes of juvenile myopia patients. Using a tree shrew model, the study aims to explore how immune cells and nerve health are affected in the optic nerve head, which may contribute to the progression of myopia. By employing advanced imaging techniques and protein profiling, researchers will correlate these microscopic changes with observable alterations in eye structure. This work seeks to enhance our understanding of myopia's development and pave the way for new treatment options.
Why it matters
Potential benefit: If successful, this research could lead to innovative treatments that prevent or slow the progression of myopia in children and adolescents.
How similar studies have gone: Previous research has shown promising results in understanding myopia through similar cellular and molecular approaches, indicating potential for success in this study.
Where this research is happening
-
Legacy Emanuel Hospital and Health Center
Portland, United States Active
Researchers
- Principal investigator: Chaudhary, Priya — Legacy Emanuel Hospital and Health Center
- Study coordinator: Chaudhary, Priya
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.