Eyedrops that help control nearsightedness by increasing collagen strength in the eye
Official title: Topical Eyedrops Increasing Lysyl Oxidase Activity to Control Myopia
Funded at Iveena Delivery Systems, INC. · NIH-10603432 · Data updated 2026-11-12
This study is testing a new eyedrop called IVMED-85 that could help kids with nearsightedness by making their eyes stronger, and it aims to see if this treatment is safe and effective for slowing down worsening vision.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Iveena Delivery Systems, INC. NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project start | September 30, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $345,000 |
| NIH project number | 1R43EY034770-01 |
| Project ID | NIH-10603432 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children diagnosed with myopia who are at risk of progression to high myopia.
✕Less likely to help
Patients with other underlying eye conditions or those who do not have myopia may not benefit from this research.
What this research studies
This research investigates a new topical eyedrop called IVMED-85, designed to treat pediatric myopia, or nearsightedness, by increasing the activity of lysyl oxidase, which strengthens the collagen in the eye. The eyedrop aims to provide a non-invasive and cost-effective solution to slow down the progression of myopia, which is becoming increasingly common and can lead to serious vision problems. The study will assess the safety and effectiveness of these eyedrops in inducing collagen crosslinking in the sclera and cornea, potentially reducing the severity of myopia in patients. Preliminary results in animal models have shown promising outcomes, indicating that this approach may be beneficial for children suffering from myopia.
Why it matters
Potential benefit: If successful, this research could provide a new, effective treatment option for children with myopia, potentially reducing their risk of severe vision impairment.
How similar studies have gone: While the approach of using eyedrops to induce collagen crosslinking is novel, preliminary results in animal models suggest that similar methods may have shown promise.
Where this research is happening
-
Iveena Delivery Systems, INC.
Salt Lake City, United States Active
Researchers
- Principal investigator: Molokhia, Sarah Abdulla — Iveena Delivery Systems, INC.
- Study coordinator: Molokhia, Sarah Abdulla
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.