How myopia affects eye cells and its link to glaucoma risk
Official title: The Effect of Myopia on Retinal Ganglion Cells, Astrocytes and Vasculature, and its Relationsip to Glaucoma Susceptibility
Funded at State College of Optometry · NIH-11010024 · Data updated 2026-11-12
This study is looking at how being nearsighted might affect the cells and blood vessels in your eyes, which could increase the chance of getting glaucoma, and it's for anyone interested in understanding how myopia can lead to changes in eye health.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State College of Optometry NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | February 1, 2024 |
| Project end | January 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $161,624 |
| NIH project number | 5K08EY034545-02 |
| Project ID | NIH-11010024 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with myopia who may be at risk for glaucoma.
✕Less likely to help
Patients without myopia or those who do not have a risk of glaucoma may not benefit from this research.
What this research studies
This research investigates the relationship between myopia, or nearsightedness, and its impact on retinal cells and blood vessels, which may increase the risk of developing glaucoma. The project aims to understand the cellular mechanisms involved by utilizing advanced methodologies in cellular and electrophysiology. The principal investigator, a Clinical Instructor and PhD candidate, will work under the guidance of experienced mentors to develop skills that will help in translating findings into potential treatments. The goal is to uncover how excessive eye growth associated with myopia can lead to changes in the eye that predispose individuals to glaucoma.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of glaucoma in myopic patients, potentially reducing the risk of blindness.
How similar studies have gone: Previous research has indicated a connection between myopia and increased glaucoma risk, suggesting that this investigation builds on established findings.
Where this research is happening
-
State College of Optometry
New York, United States Active
Researchers
- Principal investigator: Lin, Carol — State College of Optometry
- Study coordinator: Lin, Carol
Related research
Other NIH-funded projects on the same topics.
-
Understanding how myopia and glaucoma are connected through eye mechanics
This study looks at how eye growth in myopia may influence glaucoma risk and what markers could identify it early.
-
Diagnostic Innovations in Glaucoma for High Myopia
A study to improve early detection of open-angle glaucoma in people with high myopia using advanced eye imaging.
-
How nearsightedness may raise glaucoma risk in retinal cells and vessels
A clinician-scientist is studying how myopia changes eye cells and blood vessels to understand why nearsighted people are more at risk for glaucoma.
-
Detecting glaucoma in people with high nearsightedness (high myopia)
This project uses new three-dimensional eye imaging and analysis to find glaucoma earlier in people with high myopia.
-
Exploring the link between myopia and glaucoma through cellular mechanisms
This study is looking at how having myopia (nearsightedness) might raise the chances of getting glaucoma, a serious eye disease, and it aims to find ways to help protect your vision by tracking changes in your eyes over time.
-
IOP and CSF Pressure in Glaucoma Risk
This grant studies how eye pressure and cerebrospinal fluid pressure together influence glaucoma risk and vision loss.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.