Spectacle lens with passive red light to slow myopia in children
Official title: Clinical Investigation of a Novel Spectacle Lens on Slowing Down Juvenile Myopia Progression
Run by Essilor International · NCT06850168 · Data updated 2026-11-12
This will test whether glasses that emit passive red light can slow myopia progression in children aged 6 to 11.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 6 Years to 11 Years |
| Sex | All |
| Enrollment | 35 (estimated) |
| Sponsor | Essilor International Industry-sponsored |
| Locations | 1 site (Singapore) |
| Status | Recruiting |
| Started | June 26, 2025 |
| Main results expected | October 2027 |
| Study ends | December 2027 |
| Registry record updated | August 7, 2025 |
| Trial ID | NCT06850168 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Children aged 6 to under 11 years with spherical equivalent refraction between −0.75 D and −5.00 D, astigmatism ≤2.50 D, anisometropia ≤1.00 D, good best-corrected visual acuity, no ocular or systemic conditions affecting refraction, and willingness to wear spectacles ≥12 hours/day and complete two years of follow-up.
✕Probably not a fit
Children with ocular or systemic diseases that affect refractive status, binocular vision anomalies, amblyopia, prior myopia-control treatments, or inability to meet the wear-time or visit commitments are unlikely to benefit or be eligible.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The trial compares standard single-vision and myopia-control spectacle lenses with matching versions that emit passive red light over a two-year period, using single-vision lenses in year one and myopia-control lenses in year two. Children will be asked to wear the assigned spectacles for more than 12 hours per day and attend regular follow-up visits at the Essilor R&D Centre in Singapore. Outcomes include changes in spherical equivalent refraction and axial length, along with safety and compliance monitoring. The design is exploratory and focuses on whether passive red-light emission adds measurable myopia control compared with standard lenses.
Why it matters
Potential benefit: If successful, these lenses could slow axial elongation and reduce the rate of myopia progression in children, lowering their long-term risk of high myopia.
How similar studies have gone: Some clinical work using repeated low-level red-light therapy has shown promising reductions in axial elongation, but embedding passive red-light emission into everyday spectacles is a newer and less-tested approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Children equal to or greater than 6 years old and less than 11 years at the time of signing informed consent. * Corrected spherical equivalent refraction (SER) between -0.75 D and -5.00 D with astigmatism not more than 2.50 D. * Difference in SER (Anisometropia) between two eyes should not exceed 1.00 D. * Best corrected visual acuity better than or equal to +0.10 log MAR (20/25 or better with Snellen). * Be in good general health, based on his/her and parent's/guardian's knowledge. * Agree to wear spectacles for \>12 hours/day and at least 6 days/week. * Willingness and ability to participate in investigation for 2 years and attend scheduled visits. Exclusion Criteria: * Any ocular or systemic pathologies known to affect refractive status (e.g. keratoconus, diabetes, Down's syndrome etc.) * Any binocular vision anomalies * Amblyopia * Use of prior myopia control treatment like specialized myopia control spectacles and contact lenses at least in the previous one month. * Current use of ocular or systemic medications which, in the investigator's opinion, may significantly affect pupil size, accommodation or refractive state. * Participation in any clinical investigation within 30 days of the baseline visit.
Where it's running
-
Essilor R&D Centre Singapore
Singapore, Singapore Recruiting
Study contacts
- Principal investigator: Andrew Tan — Essilor R&D Centre Singapore
- Study coordinator: Celine Carimalo
- Email: carimalc@essilor.com.sg
- Phone: +65 67134617
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Evaluating a device for screening vision problems in young children
This study is testing a new device to see if it can effectively find vision problems in children aged 3 to 8, whether they wear glasses or not.
-
Optimizing light exposure to prevent and control myopia in children
This study tests if changing classroom lighting to mimic sunlight or using a smartphone app to guide light exposure can help prevent and control myopia in primary school children.
-
Hyperopic reserve screening for kindergartners in Beijing
A population-wide screening tests whether senior kindergarten children in Beijing have enough hyperopic reserve to help prevent future myopia.
-
Do dual-focus multifocal contact lenses improve hand-eye coordination and sports vision compared with your usual lenses
This study tests whether wearing dual-focus multifocal contact lenses improves hand-eye coordination and sports vision in adults who play baseball or softball and normally wear contact lenses.
-
Two monthly silicone hydrogel multifocal toric contact lenses in wearers with astigmatism and myopia
This study tests whether two popular soft multifocal toric contact lenses perform differently in adults who need vision correction for astigmatism and myopia.
-
Seeing clearly in low light after Ray-Tracing guided LASIK
A trial tests how well WaveLight Plus LASIK works for people with myopia and astigmatism and whether patients are satisfied after the procedure.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.