Longitudinal analysis of spine and vision health in adolescents in Zhejiang

Zhejiang Adolescent Spine and Vision Health Cohort: A Longitudinal Database Analysis

Observational Second Affiliated Hospital of Wenzhou Medical University · NCT06992622

This study looks at how common scoliosis and vision problems are in kids and teens aged 6-18 in Zhejiang, and tracks changes in their spine and eyesight over eight years while providing health education to help catch issues early.

Quick facts

Study typeObservational
Enrollment73000 (estimated)
Ages6 Years to 17 Years
SexAll
SponsorSecond Affiliated Hospital of Wenzhou Medical University Academic / other
Locations1 site (Wenzhou, Zhejiang)
Trial IDNCT06992622 on ClinicalTrials.gov

What this trial studies

This study investigates the prevalence of scoliosis, myopia, and other vision disorders in adolescents aged 6-18 in Zhejiang Province. It aims to track changes in spinal curvature over an 8-year period while analyzing the associations between scoliosis and vision disorders, as well as potential risk factors. The study also includes health education on scoliosis during screenings to promote early detection and intervention. By focusing on a longitudinal approach, it seeks to understand the dynamics of these conditions in a pediatric population.

Who should consider this trial

Good fit: Ideal candidates for this study are adolescents aged 6 to 17 diagnosed with idiopathic scoliosis and exhibiting specific spinal curvature measurements.

Not a fit: Patients with scoliosis due to non-idiopathic causes or those with significant comorbid conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved early detection and management of scoliosis and vision disorders in adolescents.

How similar studies have performed: While there have been various studies on scoliosis prevalence, this longitudinal approach focusing on both spine and vision health in adolescents is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Diagnosis of idiopathic scoliosis at their first clinic visit
* Skeletally immature (Risser Sign 0-3)
* Cobb angle between 11-40 degrees
* Age between 6 and 17

Exclusion Criteria:

* • Patients with scoliosis other than idiopathic, or with other musculoskeletal or neurodevelopmental conditions that might be responsible for the scoliosis

  * History of previous spine surgery or spinal injury
  * Tumor or malignant tumor in the spine
  * Leg length discrepancy more than 20 mm
  * Previous diagnosis or treatment of SDB more than 6 months ago
  * Plans to relocate within the next 24 months

Where this trial is running

Wenzhou, Zhejiang

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Scoliosis IdiopathicMyopiaVision DisordersAdolescent idiopathic scoliosisLongitudinal progressionSpine-vision comorbidity
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.