Understanding vision problems and myopia in premature infants
The Underlying Mechanisms of Visual Impairment and Myopia in Prematurity
['FUNDING_R01'] · OAKLAND UNIVERSITY · NIH-10923798
This study is looking at how babies born early might develop vision problems, like nearsightedness, by examining the natural activity in their eyes that helps them grow properly, with the hope of finding ways to prevent or treat these issues.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | OAKLAND UNIVERSITY (nih funded) |
| Locations | 1 site (ROCHESTER, UNITED STATES) |
| Trial ID | NIH-10923798 on ClinicalTrials.gov |
What this research studies
This research investigates how visual impairment and myopia develop in infants born prematurely. It focuses on the role of spontaneous neuronal activity in the retina, known as retinal waves, which are crucial for normal eye development. By studying the mechanisms behind these processes, the research aims to identify potential preventive and therapeutic strategies for vision issues associated with prematurity. The study will utilize animal models to explore the cellular and molecular factors involved in these conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are infants born prematurely, particularly those at risk for visual impairment or myopia.
Not a fit: Patients who are not premature or do not have any visual impairment or myopia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that prevent or reduce vision impairment and myopia in premature infants.
How similar studies have performed: Other research has shown promise in understanding the mechanisms of visual impairment in premature infants, but this specific approach is exploring novel aspects of retinal development.
Where this research is happening
ROCHESTER, UNITED STATES
- OAKLAND UNIVERSITY — ROCHESTER, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ZHANG, DAO-QI — OAKLAND UNIVERSITY
- Study coordinator: ZHANG, DAO-QI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.