Identifying a blood biomarker for brain injury after spontaneous bleeding in the brain
Advancing a Prognostic and Monitoring Biomarker of Neutrophil-driven Secondary Brain Injury in Spontaneous Intracerebral Hemorrhage for Neurotherapeutics Development
This study is looking at a specific blood marker that could help doctors predict and track brain injury in people who have had a serious type of stroke called spontaneous intracerebral hemorrhage, so they can better understand how to treat and monitor their recovery.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University Medical Campus NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11042395 on NIH RePORTER |
What this research studies
This research focuses on spontaneous intracerebral hemorrhage (sICH), a severe type of stroke that leads to high rates of death and disability. The goal is to identify a specific blood biomarker related to neutrophil activity that can predict and monitor secondary brain injury in patients. By analyzing a unique subset of neutrophils, the study aims to develop a standardized method for measuring this biomarker, which could help in better patient stratification for clinical trials and monitoring disease progression. The research will involve a diverse group of patients who have experienced this type of brain injury.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients who have experienced spontaneous intracerebral hemorrhage without anticoagulant therapy or immunological deficiencies.
Not a fit: Patients with other types of strokes or those receiving anticoagulant therapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prognostic tools and monitoring strategies for patients suffering from spontaneous intracerebral hemorrhage.
How similar studies have performed: While this approach is innovative, it builds on previous research that has explored biomarkers in brain injury, indicating potential for success.
Where this research is happening
Boston, United States
- Boston University Medical Campus — Boston, United States (Active)
Researchers
- Principal investigator: Herrera, Victoria L — Boston University Medical Campus
- Study coordinator: Herrera, Victoria L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.