Identifying biomarkers and imaging markers for intracerebral hemorrhage

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on intracerebral hemorrhage (ICH), a severe type of stroke that leads to high mortality and disability. Researchers aim to discover potential biomarkers by analyzing blood, cerebrospinal fluid, urine, saliva, and tissue samples from ICH patients, alongside conducting multimodal imaging scans such as CT, MRI, MRS, and PET. The goal is to enhance understanding of the pathophysiological mechanisms of ICH and develop new tools for diagnosis, monitoring, and prognosis. By correlating molecular and imaging markers, the study seeks to improve therapeutic decisions and risk stratification for affected patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Individuals aged 18-80 years
2. Hematoma size is more than 5 ml
3. Evidence of a spontaneous ICH on CT scan
4. Patient within 72 hours of ictus
5. Glasgow Coma Scale (GCS) Score of 5-15.
6. The history of hypertension

Exclusion Criteria:

1. Individuals with age \< 18 years or \> 80 years
2. Clear evidence that the hemorrhage is due to an aneurysm, arteriovenous malformation or other cerebrovascular diseases.
3. ICH secondary to tumor or trauma..
4. If the haematological effects of any previous anticoagulants are not completely reversed.
5. Patients with heart insufficiency, lungs insufficiency, renal insufficiency, hepatic insufficiency, autoimmune diseases and other organ diseases with severe dysfunction.

Where it's running

• Department of Neurosurgery , Southwest Hospital, Third Military Medical University,
  Chongqing, Chongqing Municipality, China Recruiting

Study contacts

• Principal investigator: Rong Hu, Ph.D — Southwest Hospital, China
• Study coordinator: Rong Hu, Ph.D
• Email: huchrong@aliyun.com
• Phone: 86-23-68765761

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.