Investigating a new treatment for brain injuries caused by bleeding in the brain.
BEACH: Biomarker and Edema Attenuation in IntraCerebral Hemorrhage Phase 2a Trial
This study is looking at how a new medication called MW189 can help people who have had serious brain injuries from bleeding in the brain, by reducing inflammation and hopefully helping them recover better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10997367 on NIH RePORTER |
What this research studies
This research focuses on patients who have suffered from acute brain injuries, particularly those caused by intracerebral hemorrhage (ICH). It aims to evaluate the safety and effectiveness of a new medication, MW189, which targets inflammation in the brain that can worsen damage after such injuries. By reducing harmful inflammatory responses, the study hopes to improve recovery outcomes for patients. Participants will be monitored closely to assess the impact of the treatment on their neurological health.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 who have experienced an acute brain injury, specifically intracerebral hemorrhage.
Not a fit: Patients with chronic brain injuries or those not experiencing acute symptoms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved recovery and reduced complications for patients with acute brain injuries.
How similar studies have performed: Previous research has shown promise in targeting inflammation for improving outcomes in brain injury, making this approach both relevant and potentially impactful.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Hanley, Daniel F — Johns Hopkins University
- Study coordinator: Hanley, Daniel F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.