Investigating how brain hemorrhage affects tissue damage and recovery using MRI.
Human Intracerebral Hemorrhage: Impact of Hematoma Size, Hemolysis and Iron Overload on Edema and White Matter Survival by MRI
This study is looking at how bleeding in the brain affects brain tissue over time using special MRI scans, to help us understand recovery and find better treatments for people who have had a brain bleed.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-11036320 on NIH RePORTER |
What this research studies
This research focuses on understanding the impact of intracerebral hemorrhage (ICH) on brain tissue by using advanced MRI techniques. It aims to track changes in brain tissue over time, particularly looking at how the size of the hemorrhage and the presence of iron affect swelling and the survival of white matter. By analyzing MRI markers from the acute phase to chronic recovery, the study seeks to provide insights into the natural progression of ICH and identify potential indicators of recovery. This could help in developing better treatment strategies for patients suffering from ICH.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced an intracerebral hemorrhage and are within the acute to chronic recovery phases.
Not a fit: Patients who have not experienced an intracerebral hemorrhage or those with chronic neurological conditions unrelated to ICH may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prognostic tools and treatment options for patients with intracerebral hemorrhage.
How similar studies have performed: Previous studies using MRI to evaluate brain hemorrhage have shown promising results, indicating that this approach could yield valuable insights into patient outcomes.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Chaudhary, Neeraj — University of Michigan at Ann Arbor
- Study coordinator: Chaudhary, Neeraj
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.