Understanding brain and heart injuries after bleeding in the brain

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the mechanisms of brain and heart injuries that occur following an intracranial hemorrhage, particularly focusing on the cerebrocardiac syndrome. Patients aged 18 and older with confirmed acute intracranial hemorrhage will be enrolled and undergo a multi-disciplinary assessment to evaluate both cerebral and cardiac complications. The study seeks to clarify the pathophysiological processes involved and their implications for diagnosis and treatment strategies. By analyzing these mechanisms, the research hopes to enhance understanding of the relationship between brain injuries and cardiac complications.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients aged 18 years or older at the time of enrollment.
2. Acute intracranial hemorrhage confirmed by neuroimaging (CT, MRI，CTA, MRA, or DSA) within 48 hours of symptom onset.
3. Ability to provide informed consent or have a legally authorized representative willing to consent on their behalf.

Exclusion Criteria:

1. Patients who refuse to participate in the study or cannot provide informed consent.
2. Patients with a history of significant cardiovascular disease, including myocardial infarction, heart failure, or arrhythmias, unless stable and well-controlled.
3. Patients who have undergone cardiac bypass surgery, stent placement, or other cardiovascular interventions within the past 6 months.
4. Patients with active brain tumors, ischemic stroke within 3 months or a history of previous brain injury that could confound the study findings.
5. Patients with active malignant disease, severe inflammatory or infectious disease, or those who have undergone surgery for any reason within the past 3 months.
6. Patients with any condition that, in the opinion of the investigator, would make it unsafe or impractical to participate in the study.

Where it's running

• Beijing Tiantan Hospital Affiliated to Capital Medical University
  Beijing, Beijing Municipality, China Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.