Condition
Stroke, Ischemic clinical trials and research
As of November 12, 2026, Find a Trial lists 84 Stroke, Ischemic clinical trials that are recruiting, at sites in 38 countries (most in United States (20), China (19), France (9)). 1 was first registered in the last 30 days. By phase: Phase 3 (9), Phase 4 (3), Phase 2 (2), Phase 2/3 (1). The most active sponsors are General Hospital of Shenyang Military Region (5), Xuanwu Hospital, Beijing (4), Chinese University of Hong Kong (4). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 84Clinical trials
- 1New in 30 days
- 38Countries
Newest Stroke, Ischemic clinical trials
All recruiting trials (84)
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Paired VNS: How the Brain and Pupils Respond in Stroke Patients
This study tests real-time physiologic responses to paired VNS in adults with chronic motor impairment after ischemic stroke to help tailor dosing.
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NeuroAiD test in mild to moderate ischemic stroke patients
This study tests whether adding MLC901 (NeuroAiD II) to standard stroke care helps adults who recently had an ischemic stroke recover better than standard care alone.
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Using IMPROVE to guide carotid revascularisation decisions
This trial tests whether using the IMPROVE MRI-based score to select patients for carotid revascularisation is as good as standard care based mainly on stenosis degree, among people who have had a recent stroke or TIA due to carotid disease.
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High-intensity interval versus moderate continuous exercise for stroke-related muscle loss
This will test whether high-intensity interval training (HIIT) or moderate-intensity continuous training (MCIT) better helps people 1–6 months after an ischemic stroke who have muscle loss regain muscle mass, strength, walking ability, and quality of life.
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Test of adding a very low-dose edoxaban to standard antiplatelet therapy to prevent another stroke in adults 75 and older
This trial tests whether adding a tiny amount of edoxaban to aspirin or clopidogrel can better prevent a second stroke in people aged 75+ who recently had an ischemic stroke.
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HR-MRI–Directed Tirofiban Therapy for Late-Window ICAS-LAA Stroke
We’re testing whether tirofiban plus dual antiplatelet therapy, guided by high-resolution MRI of the brain’s blood vessels, can help people with intracranial large-artery atherosclerosis strokes that begin more than 24 hours after onset.
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Perfusion-guided endovascular treatment for medium-vessel ischemic stroke
This trial will test whether using perfusion imaging to guide endovascular treatment helps adults with medium-vessel ischemic stroke (within 24 hours of last-known-well) recover better than standard medical care.
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MRI-derived Pressure Ratio (MPR) to predict stroke risk in intracranial atherosclerosis (ICAS)
This study will test whether a new MRI-derived pressure ratio (MPR) can help predict 1-year stroke risk in adults (18–80) with 50–99% intracranial atherosclerotic stenosis in the anterior circulation.
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Dulaglutide for improving blood flow in severe intracranial artery narrowing
This trial will test whether dulaglutide can improve cerebral blood flow reserve in adults who recently had a TIA or mild ischemic stroke from severe narrowing of the intracranial carotid or middle cerebral artery.
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Vojta therapy to improve posture and trunk control after stroke
This study will see if adding Vojta reflex locomotion therapy to routine physical therapy helps adults with recent ischemic stroke improve posture, trunk control, and arm movement.
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Prefrontal brain stimulation to reduce post-stroke fatigue and improve aphasia
This trial tests whether mild electrical stimulation (tDCS) to the front of the brain combined with speech therapy can reduce fatigue and improve language and attention in people with chronic left-hemisphere ischemic stroke and mild-to-moderate aphasia.
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IV tirofiban given before clot removal for anterior large-vessel ischemic stroke
This trial will test whether giving IV tirofiban before endovascular clot removal helps people with anterior-circulation large-vessel ischemic stroke due to intracranial atherosclerosis.
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How vision can recover after an occipital stroke
This project will use brain MRI and vision testing to see if patterns of residual brain tissue and prior or ongoing visual training relate to partial vision recovery in people with occipital stroke and homonymous field loss.
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Early prophylactic decompressive hemicraniectomy after endovascular thrombectomy for large hemispheric ischemic infarcts
This trial will test if doing an early decompressive hemicraniectomy right after successful endovascular thrombectomy helps people with large-core anterior circulation ischemic strokes avoid dangerous brain swelling and recover better.
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Robotic balance training with brain stimulation to improve balance after stroke
This program tests whether adding noninvasive brain stimulation to robotic balance training helps people with chronic stroke who still have balance and walking problems.
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PET/MR multimodal analysis of brain blood flow and metabolism in carotid ischemia
This project uses combined PET and MRI scans to test whether measuring cerebral blood flow and glucose metabolism helps guide diagnosis and treatment for people with significant carotid artery narrowing who had a recent ischemic stroke or TIA.
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Predicting recovery after thrombolysis and thrombectomy using brain scan scores
This project will see if combining standard brain imaging scores can predict 90-day recovery and vessel reopening in adults who had an acute ischemic stroke treated with clot-busting medicine and clot removal.
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Tenecteplase for adults with medium-vessel ischemic stroke treated 4.5–24 hours after last seen well
This trial will test whether a single dose of tenecteplase helps adults with medium-vessel ischemic stroke when given 4.5 to 24 hours after they were last seen well.
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Rehabilitation program for lateropulsion after stroke using exoskeleton-assisted exercises
This trial tests a 3-week, exoskeleton-supported rehabilitation program to help people who have lateropulsion after right-hemisphere ischemic stroke see if their sense of vertical is improved.
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Brain resilience after a minor ischemic stroke (BREMISS)
This project will try to build a model that predicts quality of life more than four years after a minor ischemic stroke using patients' initial clinical data, optional MRI and saliva samples, and questionnaires.
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Examining brain blood flow in stroke patients with motor dysfunction
This study is testing how blood flow in the brain relates to movement problems in stroke patients to see if it can help us understand their recovery better.
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Urgent versus delayed carotid endarterectomy after a TIA or minor stroke
This trial tests whether doing carotid endarterectomy within 3 days instead of waiting 4–15 days better prevents death, stroke, or heart attack in adults 45–90 with symptomatic carotid narrowing after a TIA or minor stroke.
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Effectiveness of a new neurorehabilitation technology for stroke recovery
This study is testing a new rehabilitation technology that uses robots and virtual reality to see if it can help stroke patients recover better than regular therapy.
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Stem cell therapy for chronic stroke recovery
This study is testing whether using a patient's own stem cells can help people with long-term stroke recovery feel better and improve their daily functioning.
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Emergency Stroke Unit for treating acute strokes
This study is testing a new Emergency Stroke Unit that uses a mobile MRI to see if it can help treat stroke patients faster and improve their recovery.
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Evaluating antiplatelet therapy for cerebral small vessel diseases
This study is testing if different blood-thinning medications can help people aged 30 to 79 with small vessel disease in the brain feel better and improve their condition.
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Cognitive job accommodation for stroke patients returning to work
This study tests if special job support can help people who have had a stroke return to work and perform better on the job.
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Validation of the Polish Fatigue Severity Scale
This study is testing a Polish version of a questionnaire to see how well it measures fatigue in people with multiple sclerosis, ALS, and stroke.
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Tenecteplase versus alteplase before mechanical thrombectomy for acute large-vessel ischemic stroke
This trial tests whether tenecteplase given before mechanical thrombectomy helps adults with acute large-vessel ischemic stroke within 4.5 hours recover better than standard alteplase.
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Program to help stroke survivors manage their health
This study is testing a program that helps stroke survivors manage their health and reduce the risk of another stroke by using smart devices and working with healthcare providers, to see if starting right after leaving the hospital is more effective than starting later.
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Creatine supplementation to aid recovery after ischemic stroke
This study is testing if taking creatine can help people recover better and regain strength after having an ischemic stroke.
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Carotid artery stenting during treatment of acute stroke
This study is testing if adding carotid artery stenting during a stroke treatment can help improve blood flow to the brain and lower the chances of having another stroke for patients with blocked carotid arteries.
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Improving motor recovery after stroke using brain stimulation
This study is testing a new brain stimulation device to see if it can help people recover movement in their arms after having a stroke.
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Cognitive training and health coaching for stroke survivors and their families
This study is testing a new online program that helps stroke survivors and their family members improve brain health and reduce stroke risk through cognitive training and health coaching.
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Comparing two techniques for improving trunk control and mobility in stroke patients
This study is testing two different rehabilitation methods to see which one helps stroke patients improve their trunk control and mobility better.
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Assessing stroke phases using Traditional Chinese Medicine diagnostic tools
This study is testing whether Traditional Chinese Medicine tools, like tongue and pulse diagnosis, can help understand the different stages of ischemic stroke in patients over 40 who are recently diagnosed.
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Exploring the effects of remote ischemic preconditioning on stroke recovery
This study is testing if a special treatment called remote ischemic preconditioning can help improve blood flow and recovery in stroke patients with poor circulation after their stroke.
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Endovascular therapy for mild ischemic stroke with large vessel occlusion
This study is testing if a special procedure called endovascular therapy can help people who have had a mild stroke with worsening symptoms feel better compared to just receiving standard medical care.
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Comparing reactive balance training with and without electrical stimulation for stroke recovery
This study is testing whether adding electrical stimulation to balance training can help people who have had a stroke improve their balance better than training without it.
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Monitoring brain-derived tau levels in acute ischemic stroke patients
This study is testing how brain-derived tau levels change in stroke patients over 48 hours to see if it can help understand their condition and improve treatment decisions.
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Visual retraining after stroke
We will try an intensive home-based visual retraining program for adults with cortical vision loss after stroke to see if it improves visual perception and everyday use of vision.
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Using the Atalante exoskeleton to help stroke patients walk again
This study is testing if using the Atalante exoskeleton can help stroke patients walk better compared to regular therapy.
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Evaluating how significant carotid stenosis affects retinal blood flow using automated oximetry
This study is testing how narrowing of the carotid artery affects blood flow in the retina to see if more severe narrowing leads to less blood flow.
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Using norepinephrine to induce hypertension in patients with acute ischemic stroke
This study is testing if using norepinephrine to raise blood pressure can help people who have had an acute ischemic stroke and are showing early signs of worsening symptoms.
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Understanding how vision loss affects driving in virtual reality
This study tests how vision loss from a stroke affects driving skills in a virtual reality setting to help understand the challenges faced by people with visual field defects.
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Using Tenecteplase for Stroke Treatment Between 4.5 to 6 Hours After Onset
This study is testing if a medication called tenecteplase can help people who have had a stroke between 4.5 to 6 hours after their symptoms started.
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Evaluating C7 Nerve Transfer for Stroke Recovery
This study is testing if a surgery that connects a healthy part of the brain to the arm can help people who haven't improved their arm function after a stroke for 1-5 years.
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Catheter-based closure of the left atrial appendage to prevent strokes in patients with atrial fibrillation
This study is testing if a new catheter procedure using the WATCHMAN device can help prevent strokes in patients with atrial fibrillation who are still at high risk despite taking blood thinners.
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Comparing endovascular treatment and medical management for stroke patients with disabilities
This study is testing whether a procedure called endovascular thrombectomy can help stroke patients with existing disabilities feel better compared to just using medication.
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Early rehabilitation using EEG neurofeedback for stroke recovery
This study tests if using brainwave feedback along with regular rehab can help stroke patients recover better use of their arms.
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Detecting Atrial Fibrillation in Patients After Stroke
This study is testing a new smartwatch tool to see if it can help find atrial fibrillation in people who have had a stroke, to reduce their risk of having another one.
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Evaluating the effects of EECP treatment on patients with mild strokes
This study is testing if a special treatment called EECP can help people who have had mild strokes feel better and prevent further problems.
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Investigating heart inflammation after a stroke
This study is trying to see if heart inflammation is linked to strokes by comparing heart health in stroke patients and those with other neurological symptoms.
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Longitudinal study on stroke recovery and biomarkers
This study looks at how stroke survivors recover over time by tracking their brain and thinking skills along with changes in their blood to see what helps them get better.
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Predicting stroke risk using extracellular vesicles in TIA patients
This study is trying to see if certain tiny particles in the blood can help predict which patients who have had a Transient Ischemic Attack (TIA) are at higher risk for having a stroke later on.
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Improving hand and arm recovery after stroke using electrical stimulation
This study is testing if using electrical stimulation along with rehabilitation can help people who have had a stroke regain movement in their hands and arms.
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Evaluating real-world effectiveness of endovascular thrombectomy for stroke in the Asia-Pacific region
This study is testing how well a procedure called endovascular thrombectomy works for adults with a certain type of stroke in real-life situations across the Asia-Pacific region.
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Using brain network properties to improve non-invasive brain stimulation after stroke
This study is testing if understanding brain network differences can help improve brain stimulation treatments for people who have had a stroke.
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Using an implantable cardiac monitor to detect atrial fibrillation in stroke patients
This study is testing whether an implantable heart monitor can help find atrial fibrillation in stroke patients to see if it can lead to better treatment and prevent future strokes.
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Using colchicine and ticagrelor to prevent ischemic stroke in patients with atherosclerosis
This study is testing if a combination of low-dose colchicine and ticagrelor can help prevent future strokes in people with atherosclerosis who have already had an ischemic stroke.
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Observational study of stroke management and outcomes at Akershus University Hospital
This study looks at how patients with strokes are treated at Akershus University Hospital to see how well different treatments work and why some patients don’t receive certain therapies.
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Validation of biomarkers for recovery outcomes after stroke
This study is testing if certain biological markers can help predict how well patients will recover their arm movement after having a stroke.
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Using brain stimulation to improve language skills after a stroke
This study is testing if combining brain stimulation with speech therapy can help Polish-speaking patients improve their language skills after having a stroke.
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Registry for Endovascular Thrombectomy in Acute Ischemic Stroke in Taiwan
This study collects information from patients in Taiwan who have had a stroke and received a specific treatment called endovascular thrombectomy to see how well it works and how safe it is.
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How thinking affects relearning arm movements after stroke
This project tests whether adding an error-augmentation feedback method helps people who had a recent stroke, especially those with thinking or memory problems, relearn upper-arm movements.
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Investigating how circadian factors affect recovery after ischemic stroke
This study is trying to see how sleep patterns and body clock factors affect recovery in people who have had an ischemic stroke.
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Simple non-contrast CT versus advanced imaging to choose thrombectomy for acute large-vessel stroke
This trial tests whether a simple non-contrast CT scan (using ASPECTS) works as well as advanced imaging (CT perfusion or MRI) to decide if people with acute large-vessel ischemic stroke should have thrombectomy.
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Comparing two treatments for acute ischemic stroke
This study is testing two different treatments for acute ischemic stroke to see which one helps patients recover better after 90 days.
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Predicting and diagnosing spasticity after acute stroke
We will test whether a new neurophysiological measure (TSRT and its velocity sensitivity, mu) can detect and track developing spasticity during the first three months after an acute middle cerebral artery stroke in people with arm or leg weakness.
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Using amantadine to help stroke recovery
This study tests if the medication amantadine can help people recover better after having a stroke.
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Identifying echocardiographic predictors of atrial fibrillation
This study is testing if certain heart ultrasound measurements can help find atrial fibrillation in patients who have had a stroke or a mini-stroke.
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Collecting data from patients admitted to the Stroke unit
This study is collecting health information from patients in the Stroke unit to help improve future stroke care and research.
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Neuroprotective treatment for patients with ischemic stroke undergoing endovascular therapy
This study is testing a new treatment that delivers protective medicine directly into the arteries of stroke patients during a procedure to see if it helps them recover better and reduces brain damage.
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NobleStitch EL versus Amplatzer device for closing a patent foramen ovale after stroke
This trial will test whether the NobleStitch EL suture closure works as well and is as safe as the Amplatzer occluder for adults 18–60 with a patent foramen ovale who had a cryptogenic ischemic stroke.
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Investigating Monocytes in Heart Attack and Stroke Patients
This study is trying to see how certain immune cells in the blood behave in heart attack and stroke patients to understand their role in healing and find possible signs of tissue damage.
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Analyzing non-coding RNA in patients with acute ischemic stroke undergoing endovascular treatment
This study is trying to see if certain types of RNA in patients with acute ischemic stroke can help predict how well they will do after receiving endovascular treatment.
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Examining urinary disorders in stroke patients during rehabilitation
This study looks at how urinary problems affect stroke patients during their rehabilitation to see how well different treatments work for them.
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Research on health inequality and genetic disparity in cardiovascular diseases
This study is trying to understand how health differences and genetics affect heart diseases in people from various ethnic backgrounds in the UK to help improve treatments for everyone.
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Intensive statin therapy for ischemic stroke with intracranial atherosclerotic plaques
This study is testing whether stronger doses of statin medication can help people who have had an ischemic stroke due to plaque buildup in their brain arteries.
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Longitudinal study on brain health and risk factors for neurological diseases
This study is trying to understand how different health factors affect brain health over time in people who are at risk for conditions like stroke and dementia.
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Understanding motor recovery after stroke
This study is tracking how people recover movement in their arms after a stroke to see what helps them get better and to improve rehabilitation methods.
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Biobank for stroke and related genetic research
This study is collecting blood and tissue samples from patients to help researchers learn more about the genetic causes of stroke and related diseases.
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Rehabilitation of vision after brain injury
This study is testing a training program to help people who have had brain injuries, like strokes, improve their vision and quality of life.
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Registry for monitoring neurovascular products used in treating brain aneurysms and strokes
This study is tracking how well Medtronic devices work and their safety for people being treated for brain aneurysms and strokes.
Related topics
Quick answers
How many Stroke, Ischemic clinical trials are recruiting right now?
84, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 38 countries. The most sites are in United States (20 trials), China (19 trials), France (9 trials), Germany (5 trials), Hong Kong (5 trials). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 3: 9, Phase 4: 3, Phase 2: 2, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.