Understanding how the aging brain changes after a type of stroke called intracerebral hemorrhage
Quantitative proteomic analysis of the aging brain after intracerebral hemorrhage
This study is looking at how the aging brain changes after a serious stroke called intracerebral hemorrhage, to help us understand why older adults may struggle more with recovery, and it aims to find better treatment options for them.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Augusta University NIH-funded |
| Lab location | 1 site (Augusta, United States) |
| Project ID | NIH-10708753 on NIH RePORTER |
What this research studies
This research investigates the molecular changes that occur in the aging brain following an intracerebral hemorrhage (ICH), a severe type of stroke. By using advanced techniques like mass spectrometry, the study aims to identify changes in proteins that could help explain why older adults are more affected by ICH. The research will focus on specific brain cells involved in damage and repair processes, providing insights that could lead to better treatment options for elderly patients. Ultimately, this work seeks to fill a critical gap in understanding how age influences recovery from this condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are elderly individuals who have experienced an intracerebral hemorrhage.
Not a fit: Patients who are younger or have not experienced an intracerebral hemorrhage may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for improving recovery and neurological outcomes in elderly patients who suffer from intracerebral hemorrhage.
How similar studies have performed: While research on stroke and aging is ongoing, this specific proteomic approach to understanding ICH in the elderly is relatively novel and has not been extensively tested.
Where this research is happening
Augusta, United States
- Augusta University — Augusta, United States (Active)
Researchers
- Principal investigator: Sukumari-Ramesh, Sangeetha — Augusta University
- Study coordinator: Sukumari-Ramesh, Sangeetha
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.