Monitoring heart function in patients with brain injuries
Non-invasive Continuous Hemodynamic Monitoring in Acute Brain Injury
University of Chicago · NCT06725108
This study looks at how heart function affects recovery in people with brain injuries by tracking their health data after they leave the hospital.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | University of Chicago (other) |
| Locations | 1 site (Chicago, Illinois) |
| Trial ID | NCT06725108 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate the relationship between heart function and outcomes in patients with traumatic brain injuries and nontraumatic intracerebral hemorrhage. It will collect data from the Starling Monitor and patient medical records as part of standard clinical care. Participants will be followed up six months after hospital discharge to assess the impact of hemodynamic monitoring on recovery. The study does not involve any clinical interventions and relies on non-invasive monitoring techniques.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 80 admitted to the Neurocritical Care Unit with traumatic brain injury or nontraumatic intracerebral hemorrhage and a Glasgow Coma Scale score of less than 9.
Not a fit: Patients with pre-existing heart failure, those showing signs of imminent brain death, or major polytrauma may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of how heart function affects recovery from brain injuries, potentially leading to improved patient outcomes.
How similar studies have performed: While this approach is observational and builds on existing monitoring practices, similar studies have shown promise in understanding the relationship between hemodynamics and brain injury outcomes.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion: Patients who are: * Admitted to the University of Chicago Medical Center Neurocritical Care Unit * Adults between 18 years and 80 * Admitted with Traumatic brain injury blunt and penetrating or nontraumatic intracerebral hemorrhage * post-resuscitation Glasgow Coma Scale (GCS) \<9 Exclusion: Patients who were: * Pre-existing heart failure * Moribund or neurological exam suggesting imminent brain death (bilateral, fixed and dilated pupils) on admission * Major polytrauma or admitted to the surgical trauma critical care service * Prisoner
Where this trial is running
Chicago, Illinois
- University of Chicago — Chicago, Illinois, United States (RECRUITING)
Study contacts
- Principal investigator: Christos Lazaridis, MD — university of Chicago attending
- Study coordinator: Farima Fakhri, MD
- Email: farima.fakhri@bsd.uchicago.edu
- Phone: 3126102482
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Traumatic Brain Injury, Intracerebral Hemorrhage, Hemodynamic, Acute brain injury, Monitoring