Condition

Stroke, Acute clinical trials and research

• 68Clinical trials
• 1New in 30 days
• 27Countries

Newest Stroke, Acute clinical trials

All recruiting trials (68)

• Music therapy after stroke

  This trial tests whether adding music therapy to standard care helps stroke patients sleep better and feel less anxious or depressed while in the hospital.

  Recruiting Universidad de Granada · Granada, Granada · NCT07899034

• Endovascular therapy plus standard care vs standard care alone for distal and medium vessel strokes

  In people with acute ischemic stroke due to distal or medium vessel blockages, this study tests whether adding endovascular treatment to the usual medical care helps improve outcomes compared with medical care alone.

  Recruiting Hospital Universitari Vall d'Hebron Research Institute · Barcelona, Barcelona · NCT07843797

• Inter-Limb Transfer after Acute Stroke

  This study tests whether practicing motor skills with the affected arm helps improve movement in the other arm after an acute stroke.

  Recruiting at 2 sites University Hospital of Mont-Godinne · Yvoir, Namur and 1 other locations · NCT07822633

• Immersive Virtual Reality in Upper-Limb Rehabilitation After Stroke

  This trial tests whether adding immersive virtual reality to standard upper-limb rehabilitation helps stroke patients recover more function and quality of life.

  Recruiting Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta · Girona · NCT07609966

• Anakinra After Endovascular Therapy for Ischemic Stroke

  This trial tests whether giving two doses of Anakinra after successful endovascular treatment can reduce brain damage and improve outcomes in adults with acute ischemic stroke.

  Recruiting at 6 sites Phase 2 Beijing Tiantan Hospital · Beijing, Beijing Municipality and 5 other locations · NCT07423975

• HR-MRI–Directed Tirofiban Therapy for Late-Window ICAS-LAA Stroke

  We’re testing whether tirofiban plus dual antiplatelet therapy, guided by high-resolution MRI of the brain’s blood vessels, can help people with intracranial large-artery atherosclerosis strokes that begin more than 24 hours after onset.

  Recruiting Phase 3 Weifang Medical University · Weifang, China/Shandong Province · NCT07379190

• Nurse-led transitional care for stroke survivors in Tanzania

  This study tests whether a nurse-led transitional care program helps Tanzanian stroke survivors and their caregivers feel more prepared for discharge, manage the condition better, and have a higher quality of life.

  Recruiting Shandong University · Dar es Salaam · NCT07319312

• Comparing ear versus neck vagus nerve stimulation plus task training for subacute stroke recovery

  This trial will test whether gentle electrical stimulation of the vagus nerve at the ear or neck, combined with task-specific arm training, helps people 3–6 months after an ischemic stroke recover arm function and thinking skills.

  Recruiting Lahore University of Biological and Applied Sciences · Lahore, Punjab Province · NCT07253870

• AI to improve telephone triage for emergency calls at CCUE Andalucía

  This project tests AI tools to help emergency call operators spot life-threatening problems like cardiac arrest, stroke, severe breathing trouble, and chest pain.

  Recruiting Centro de Emergencias Sanitarias 061 Andalucía · Málaga, Málaga · NCT07247669

• Maraviroc to improve arm and hand movement after ischemic stroke

  This trial will test whether maraviroc, started soon after ischemic stroke, helps people with partial arm weakness regain motor skills over the first three months.

  Recruiting Phase 2 University Hospital, Geneva · Geneva · NCT07080567

• One-stop approach for rapid start of endovascular clot removal

  This trial will test whether taking eligible adults with suspected large- or medium-vessel ischemic stroke straight to the angiography suite for imaging and treatment gets clot-removal therapy started faster and improves outcomes.

  Recruiting Paracelsus Medical University · Nuremberg and 1 other locations · NCT07052045

• Field‑Cycling MRI to detect early brain changes after an acute stroke

  This will test whether a new Field‑Cycling Imaging MRI can identify brain areas that might recover when used within 24 hours in adults with an acute stroke and moderate to severe symptoms.

  Recruiting University of Aberdeen · Aberdeen · NCT07004140

• Endovascular clot-removal guided by automated standard CT for late-window ischemic stroke

  This trial will test whether removing clots with endovascular therapy guided only by automated non-contrast CT can help adults with large-vessel ischemic stroke treated 6–72 hours after symptoms begin.

  Recruiting University of Iowa · Iowa City, Iowa and 1 other locations · NCT07001852

• Fusion imaging to guide clot-removal procedures for acute ischemic stroke

  This trial will test whether using CT-to-live angiography fusion imaging during endovascular thrombectomy helps doctors open blocked large brain arteries faster and more often in adults with acute ischemic stroke.

  Recruiting Region Skane · Helsinki and 3 other locations · NCT06975696

• Examining sex differences in prehospital stroke care

  This study looks at how emergency medical services treat suspected strokes in men and women differently to see if there are any gaps in care that need to be addressed.

  Recruiting Universität des Saarlandes · Homburg · NCT06865950

• Low-cost virtual reality motor rehabilitation for stroke in hospital and at home

  This trial will test whether a low-cost virtual reality motor therapy can help adults with moderate-to-severe upper-limb weakness after a first ischemic stroke recover movement both during hospital care and at home.

  Recruiting Nova Scotia Health Authority · Kentville, Nova Scotia · NCT06864741

• Direct transfer to the angiography suite versus emergency department evaluation for suspected large vessel occlusion stroke

  This trial will see if taking adults with suspected large vessel occlusion stroke directly to the angiography suite instead of first evaluating them in the emergency department helps people recover better when they arrive within 7 hours of symptom onset.

  Recruiting at 15 sites University of Iowa · New Haven, Connecticut and 14 other locations · NCT06825897

• Effectiveness of a new neurorehabilitation technology for stroke recovery

  This study is testing a new rehabilitation technology that uses robots and virtual reality to see if it can help stroke patients recover better than regular therapy.

  Recruiting Neurotechnika · Samara, Samara Oblast · NCT06753006

• Effectiveness of a new neurorehabilitation technology for stroke recovery

  This study is testing a new rehabilitation technology that uses robots and virtual reality to see if it can help stroke patients recover better than regular therapy.

  Recruiting Neurotechnika · Samara, Samara Oblast · NCT06753006

• Using AI to speed up transfers for stroke patients needing thrombectomy

  This study tests if using an AI tool can help speed up the transfer of stroke patients to hospitals that can provide a special treatment called thrombectomy.

  Recruiting at 2 sites Hospital Universitari Vall d'Hebron Research Institute · Granollers, Barcelona and 1 other locations · NCT06741332

• Emergency Stroke Unit for treating acute strokes

  This study is testing a new Emergency Stroke Unit that uses a mobile MRI to see if it can help treat stroke patients faster and improve their recovery.

  Recruiting Chinese University of Hong Kong · Hong Kong · NCT06728592

• Rescue stenting and thrombolysis for large vessel ischemic stroke

  This study tests if combining rescue stenting with a clot-busting treatment can help adults who have a severe stroke and didn't get better with standard procedures.

  Recruiting at 7 sites ASST Santi Paolo e Carlo · Bergamo, Italy and 6 other locations · NCT06727006

• Observational study of patients with spontaneous intracerebral hemorrhage

  This study is looking at patients with spontaneous brain bleeding to see how they recover and what long-term effects they might have.

  Recruiting at 6 sites First Affiliated Hospital of Fujian Medical University · Fuzhou, Fujian and 5 other locations · NCT06670456

• Tenecteplase versus alteplase before mechanical thrombectomy for acute large-vessel ischemic stroke

  This trial tests whether tenecteplase given before mechanical thrombectomy helps adults with acute large-vessel ischemic stroke within 4.5 hours recover better than standard alteplase.

  Recruiting Phase 3 Xuanwu Hospital, Beijing · Beijing, Beijing Municipality · NCT06658197

• Comparing thrombectomy and medical management for stroke patients treated after 24 hours

  This study is testing if a special procedure to remove blood clots can help stroke patients who arrive more than 24 hours after their symptoms start, compared to just using medication.

  Recruiting Tianjin Huanhu Hospital · Tianjin, Tianjin Municipality · NCT06654375

• Evaluating therapy for patients with minor strokes and large vessel occlusion

  This study is testing different treatment options for patients with minor strokes caused by blocked large blood vessels to see which ones help them recover better.

  Recruiting Sir Run Run Shaw Hospital · Hangzhou, Zhejiang · NCT06633809

• Examining joint motion problems in stroke patients and healthy volunteers

  This study is testing a physical exam method to see how well it can spot joint motion problems in stroke patients compared to healthy people.

  Recruiting University of California, Davis · Sacramento, California · NCT06605014

• Telehealth program for lifestyle changes in stroke survivors

  This study tests whether a telehealth program can help stroke survivors make healthy lifestyle changes with support from others over six months.

  Recruiting Baylor Research Institute · Dallas, Texas · NCT06569121

• Carotid artery stenting during treatment of acute stroke

  This study is testing if adding carotid artery stenting during a stroke treatment can help improve blood flow to the brain and lower the chances of having another stroke for patients with blocked carotid arteries.

  Recruiting Phase 3 University Medical Center Groningen · Groningen · NCT06511089

• Detecting brain injuries in children on ECMO using portable MRI

  This study is testing a portable MRI to see if it can help find brain injuries in children on ECMO support more quickly and accurately.

  Recruiting Children's Mercy Hospital Kansas City · Kansas City, Missouri · NCT06469801

• Understanding quality of life and stress in stroke patients and their caregivers

  This study looks at how stroke affects the quality of life and stress levels in both patients and their caregivers to see how they compare to people without stroke.

  Recruiting University of Zurich · Zurich, Canton of Zurich · NCT06443268

• Evaluating the impact of artery calcification on stroke treatment outcomes

  This study is trying to see if the amount of calcium in the arteries affects how well stroke patients do after a specific treatment for blocked blood vessels.

  Recruiting Zhujiang Hospital · Guangzhou, Guangdong · NCT06418698

• Optimizing stroke identification by ambulance paramedics

  This study is testing how well ambulance paramedics can identify strokes using different methods to see which one works best for patients.

  Recruiting Leiden University Medical Center · Leiden · NCT06332989

• Comparing different doses of tenecteplase for treating acute ischemic stroke

  This study is testing whether a standard dose or a lower dose of a medication called tenecteplase can help people who have had an acute ischemic stroke recover better and stay safe.

  Recruiting at 13 sites Phase 3 University of Calgary · Sydney, Barangaroo and 23 other locations · NCT06320431

• Wearable device to detect stroke onset

  This study is testing a wearable device to see if it can quickly detect the start of a stroke in people who have arm weakness.

  Recruiting at 10 sites Region Skane · Gothenburg and 9 other locations · NCT06315192

• Using an enriched environment to help stroke recovery in a hospital ward

  This study is testing whether creating a more engaging and supportive environment in the hospital can help stroke patients recover better and improve their overall well-being.

  Recruiting University of Padova · Padova · NCT06233682

• Observing the use of intravenous thrombolysis for acute ischemic stroke in Southwestern China

  This study looks at how safe and effective a treatment called intravenous thrombolysis is for people having an acute ischemic stroke in Southwestern China.

  Recruiting The Affiliated Hospital Of Southwest Medical University · Luzhou · NCT06131385

• Effect of rTMS on pneumonia in stroke patients with swallowing difficulties

  This study tests if adding a special brain treatment to regular therapy can help stroke patients with swallowing problems avoid pneumonia.

  Recruiting Cairo University · Giza, Giza Governorate · NCT06123650

• Monitoring brain-derived tau levels in acute ischemic stroke patients

  This study is testing how brain-derived tau levels change in stroke patients over 48 hours to see if it can help understand their condition and improve treatment decisions.

  Recruiting Ludwig-Maximilians - University of Munich · Munich, Bavaria · NCT06121336

• Using the Atalante exoskeleton to help stroke patients walk again

  This study is testing if using the Atalante exoskeleton can help stroke patients walk better compared to regular therapy.

  Recruiting at 4 sites Wandercraft · Créteil and 4 other locations · NCT06107010

• Improving emergency evaluation and transfer protocols for stroke patients

  This study is testing a new way to speed up the transfer of stroke patients to specialized hospitals to see if it helps them get better faster.

  Recruiting at 8 sites University of Chicago · New Haven, Connecticut and 7 other locations · NCT06094478

• Using norepinephrine to induce hypertension in patients with acute ischemic stroke

  This study is testing if using norepinephrine to raise blood pressure can help people who have had an acute ischemic stroke and are showing early signs of worsening symptoms.

  Recruiting Phase 3 University Hospital, Bordeaux · Bordeaux · NCT06059144

• Comparing endovascular treatment and medical management for stroke patients with disabilities

  This study is testing whether a procedure called endovascular thrombectomy can help stroke patients with existing disabilities feel better compared to just using medication.

  Recruiting at 33 sites University of Cincinnati · Birmingham, Alabama and 34 other locations · NCT05911568

• Bimanual motor skill learning for patients recovering from acute stroke

  This study tests how stroke affects learning to use both hands together and aims to find better ways to help patients recover their motor skills.

  Recruiting at 2 sites University Hospital of Mont-Godinne · Yvoir, Namur and 1 other locations · NCT05760846

• Mobile Stroke Unit deployment for acute stroke treatment

  This study is testing if using Mobile Stroke Units to start treatment for stroke patients before they reach the hospital can help them recover better than the usual care they receive.

  Recruiting at 10 sites Centre Hospitalier St Anne · Garches and 10 other locations · NCT05649670

• Evaluating real-world effectiveness of endovascular thrombectomy for stroke in the Asia-Pacific region

  This study is testing how well a procedure called endovascular thrombectomy works for adults with a certain type of stroke in real-life situations across the Asia-Pacific region.

  Recruiting at 3 sites Chinese University of Hong Kong · Linyi, Shandong and 2 other locations · NCT05578300

• Using an implantable cardiac monitor to detect atrial fibrillation in stroke patients

  This study is testing whether an implantable heart monitor can help find atrial fibrillation in stroke patients to see if it can lead to better treatment and prevent future strokes.

  Recruiting National and Kapodistrian University of Athens · Athens · NCT05494034

• Using geko device to prevent blood clots in stroke patients

  This study is testing if the geko™ device can help prevent blood clots in stroke patients who can’t move around, compared to the standard treatment they usually get.

  Recruiting at 17 sites Firstkind Ltd · Bury St Edmunds, Suffolk and 17 other locations · NCT05476913

• Observational study of stroke management and outcomes at Akershus University Hospital

  This study looks at how patients with strokes are treated at Akershus University Hospital to see how well different treatments work and why some patients don’t receive certain therapies.

  Recruiting University Hospital, Akershus · Lørenskog · NCT05378490

• Evaluating DOAC levels in Chinese patients with atrial fibrillation

  This study is testing how stopping blood-thinning medication for a short time affects Chinese patients with atrial fibrillation to see if it's safe for them during medical procedures.

  Recruiting Chinese University of Hong Kong · Hong Kong · NCT05378035

• Validation of biomarkers for recovery outcomes after stroke

  This study is testing if certain biological markers can help predict how well patients will recover their arm movement after having a stroke.

  Recruiting at 40 sites Yale University · Birmingham, Alabama and 44 other locations · NCT05338697

• Assessment of treatment strategies for stroke patients

  This study looks at different treatment methods for people who have had a stroke to see which ones help them recover better and live longer.

  Recruiting University of Giessen · Giessen, Hesse · NCT05295862

• Investigating the immune response in stroke patients

  This study is trying to see if the immune response in stroke patients affects their thinking skills and could lead to better treatments for cognitive decline after a stroke.

  Recruiting University of Oslo · Lørenskog · NCT05277129

• Simple non-contrast CT versus advanced imaging to choose thrombectomy for acute large-vessel stroke

  This trial tests whether a simple non-contrast CT scan (using ASPECTS) works as well as advanced imaging (CT perfusion or MRI) to decide if people with acute large-vessel ischemic stroke should have thrombectomy.

  Recruiting at 5 sites Xinqiao Hospital of Chongqing · Wuhu, Anhui and 7 other locations · NCT05230914

• Comparing two treatments for acute ischemic stroke

  This study is testing two different treatments for acute ischemic stroke to see which one helps patients recover better after 90 days.

  Recruiting at 13 sites Phase 3 Hospital Moinhos de Vento · Porto Alegre, Rio Grande do Sul and 12 other locations · NCT05199194

• Predicting and diagnosing spasticity after acute stroke

  We will test whether a new neurophysiological measure (TSRT and its velocity sensitivity, mu) can detect and track developing spasticity during the first three months after an acute middle cerebral artery stroke in people with arm or leg weakness.

  Recruiting McGill University · Montreal, Quebec · NCT05179473

• Collecting data from patients admitted to the Stroke unit

  This study is collecting health information from patients in the Stroke unit to help improve future stroke care and research.

  Recruiting University Hospital, Ghent · Ghent, Flanders · NCT04956185

• Optimizing Stroke Treatment Workflow for Faster Recovery

  This study is testing a new way to quickly treat stroke patients using advanced technology to see if it helps them recover faster and better than the usual methods.

  Recruiting at 17 sites Philips Clinical & Medical Affairs Global · Jacksonville, Florida and 23 other locations · NCT04701684

• Online database for evaluating stroke management quality

  This study is trying to build an online database to help improve the care of stroke patients in China by tracking their treatment and recovery over time.

  Recruiting Second Affiliated Hospital, Zhejiang University, School of Medicine · Hangzhou, Zhejiang · NCT04487340

• Treatment for acute stroke with carotid artery issues

  This study is testing if combining a procedure to open blocked carotid arteries with a treatment to remove blood clots can help people who have had a stroke feel better after 90 days.

  Recruiting Centre hospitalier de l'Université de Montréal (CHUM) · Montreal, Quebec · NCT04261478

• Analyzing non-coding RNA in patients with acute ischemic stroke undergoing endovascular treatment

  This study is trying to see if certain types of RNA in patients with acute ischemic stroke can help predict how well they will do after receiving endovascular treatment.

  Recruiting Nanjing First Hospital, Nanjing Medical University · Nanjing, Jiangsu · NCT04230785

• Using robotics to improve motor skills in patients with acute stroke

  This study is testing if a rehabilitation robot can help people who have just had a stroke learn and keep complex motor skills better than healthy individuals and those who had a stroke a while ago.

  Recruiting University Hospital of Mont-Godinne · Yvoir, Namur and 1 other locations · NCT04171856

• Using advanced MRI to study brain changes in stroke patients

  This study is testing a new MRI technique to see how stroke and TIA affect brain connections and if this helps explain the fatigue that many patients feel afterward.

  Recruiting at 2 sites Danish Research Centre for Magnetic Resonance · Copenhagen, København NV and 1 other locations · NCT04118790

• Longitudinal study on brain health and risk factors for neurological diseases

  This study is trying to understand how different health factors affect brain health over time in people who are at risk for conditions like stroke and dementia.

  Recruiting at 2 sites Chinese University of Hong Kong · Hong Kong and 1 other locations · NCT03592563

• Curved-walking training to help stroke, Parkinson’s, and femur fracture recovery

  This study tests curved-walking training to see if it helps people recovering from stroke, Parkinson’s disease, or recent femur fracture.

  Recruiting Istituti Clinici Scientifici Maugeri SpA · Lissone, Monza E Brianza · NCT03545477

• Using a wearable device to improve arm movement after stroke

  This study is testing a special device that helps stroke survivors improve their arm movement at home to see if it works better than a fake device.

  Recruiting Northwestern University · Chicago, Illinois · NCT03401762

• Analyzing blood clots in stroke patients to improve treatment outcomes

  This study looks at the blood clots from stroke patients who had a procedure to remove them to see if understanding their makeup can help improve treatment and outcomes.

  Recruiting at 11 sites Fondation Ophtalmologique Adolphe de Rothschild · Bordeaux and 11 other locations · NCT03268668

• Assessing early recovery after endovascular treatment for acute stroke

  This study looks at how well people recover in the first three months after having a special procedure to treat a stroke, to see if it helps them feel better.

  Recruiting Fondation Ophtalmologique Adolphe de Rothschild · Paris · NCT02879123

Related topics

Quick answers

How many Stroke, Acute clinical trials are recruiting right now?

68, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 27 countries. The most sites are in China (12 trials), United States (10 trials), Spain (7 trials), France (6 trials), Germany (6 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 6, Phase 2: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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