Condition

HIV Infections clinical trials and research

• 97Clinical trials
• 1NIH research projects
• 37Countries

Newest HIV Infections clinical trials

All recruiting trials (97)

• Camino HIV Prevention and Care Study

  This study tests a combined legal and peer-support program to help Latin American adults in DC and the Bay Area improve HIV testing, PrEP use, and care engagement.

  Recruiting American University · Berkeley, California and 1 other locations · NCT07834853

• VH4367310 in healthy adults: testing single increasing doses for safety and how it behaves in the body

  This study tests a single rising dose of VH4367310, a cabotegravir prodrug, to see how it behaves in the body and how safe and tolerable it is in healthy adults aged 18 to 55.

  Recruiting at 2 sites Phase 1 ViiV Healthcare · Glendale, California and 1 other locations · NCT07818915

• Online cohort of sexual and gender minorities testing digital support to boost PrEP and ART use

  In Brazil, sexually and gender diverse adults are being followed online to see if weekly WhatsApp reminders help people stick to PrEP or ART.

  Recruiting Oswaldo Cruz Foundation · Rio de Janeiro, Rio de Janeiro · NCT07772791

• Metabolic Liver Disease in People Newly Diagnosed with HIV

  This study tests whether HIV-infected adults who are starting ART are more likely to develop MASLD and related liver issues than HIV-negative adults over five years.

  Recruiting at 11 sites Guven Health Group · Ankara, Ankara and 10 other locations · NCT07737340

• Screen2Prevent: HIV screening for teens and young adults in emergency departments

  The study tests three ways of offering HIV screening to people aged 14–24 in emergency departments to see if it helps link them to PrEP or HIV treatment using digital health tools.

  Recruiting at 5 sites Westat · Tampa, Florida and 4 other locations · NCT07728123

• Long-acting LEN/TAB/ZAB vs CAB/RPV in adults with HIV-1 who are virologically suppressed on daily ART

  This study tests whether switching to a weekly-plus long-acting injectable regimen of lenacapavir, teropavimab, and zinlirvimab works as well as a two-drug injectable regimen of cabotegravir and rilpivirine for adults with HIV-1 who already have undetectable virus on daily treatment.

  Recruiting at 19 sites Phase 3 Gilead Sciences · San Francisco, California and 18 other locations · NCT07682961

• Mass Balance and Oral Bioavailability of a radiolabeled HIV drug

  This early-phase study tests how the radiolabeled VH4524184 is absorbed, distributed, metabolized, and excreted in adults with HIV.

  Recruiting Phase 1 ViiV Healthcare · Groningen · NCT07636928

• Improve access to PrEP for underserved communities in Rio de Janeiro

  The project will try offering daily oral PrEP plus on-site and digital support to HIV-negative people at higher risk in underserved areas of Rio de Janeiro to see if more people start and stay on PrEP.

  Recruiting at 2 sites Oswaldo Cruz Foundation · Nova Iguaçu, Rio de Janeiro and 1 other locations · NCT07584122

• JL18008 added to existing HIV therapy in people who have not rebuilt their CD4 cells

  This trial tests whether adding JL18008 to current HIV treatment helps people with HIV who have low CD4 counts despite good viral control.

  Recruiting Phase 1/2 Jecho Biopharmaceuticals Co., Ltd. · Beijing, Beijing Municipality · NCT07579741

• Improving HIV treatment and well-being for young men who have sex with men in Ho Chi Minh City

  This project will follow 300 young men (ages 18–24) living with HIV in Ho Chi Minh City for one year to see which social, mental health, and care factors are linked to staying on ART and keeping the virus suppressed.

  Recruiting Center for Applied Research on Men and Community Health, Vietnam · Ho Chi Minh City · NCT07559266

• First-in-human test of VH4770359 in healthy adults

  This early study will see if VH4770359 is safe and well tolerated in healthy adults and how the body processes it.

  Recruiting Phase 1 ViiV Healthcare · Baltimore, Maryland · NCT07525544

• Long-acting HIV PrEP and contraception PK study in AGYW

  This study tests how long-acting cabotegravir for PrEP interacts with hormonal contraception in young women.

  Recruiting University of Alabama at Birmingham · Bontleng, Gaborone · NCT07516548

• Doxycycline to prevent bacterial STIs in sexual and gender minorities in Rio de Janeiro.

  This research will try taking doxycycline after sex to see if it lowers the chance of syphilis, gonorrhea, and chlamydia for men who have sex with men, transgender women, and travestis in Rio de Janeiro who are living with HIV or using PrEP.

  Recruiting Oswaldo Cruz Foundation · Rio de Janeiro, Rio de Janeiro · NCT07500415

• Lenacapavir (YEZTUGO) as an HIV PrEP option in routine clinical care

  This project will see if using lenacapavir (YEZTUGO) as a PrEP option helps people at risk for HIV stay on prevention over one year in U.S. clinics.

  Recruiting at 44 sites Gilead Sciences · Birmingham, Alabama and 43 other locations · NCT07473778

• Microbiota Interventions for Accelerated Aging in People with HIV on Alcohol

  This study tests whether two safe dietary supplements—Limosilactobacillus reuteri and blueberry extract—can affect immune aging markers in people with HIV who recently used alcohol.

  Recruiting Phase 1/2 Louisiana State University Health Sciences Center in New Orleans · New Orleans, Louisiana · NCT07462767

• Bile acid and gut microbiota changes in people with hepatitis D starting bulevirtide

  This project will see if starting bulevirtide changes bile acids and gut bacteria in adults with chronic hepatitis D who are already on hepatitis B therapy.

  Recruiting Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Roma · NCT07429864

• Comparing clinic-only versus clinic plus community outreach to offer HPV self-collection for cervical screening in women with HIV

  This project will test whether adding community health worker outreach to clinic services helps more women living with HIV complete HPV self-collection for cervical screening.

  Recruiting UNC Lineberger Comprehensive Cancer Center · Kampala · NCT07428330

• Continued access for people who benefited from ViiV HIV treatment after parent studies

  This study lets people who benefited from a ViiV HIV treatment continue receiving it if they don’t have local access after completing a parent study.

  Recruiting at 4 sites Phase 3 ViiV Healthcare · Durban, KwaZulu-Natal and 3 other locations · NCT07393659

• Dasatinib to Try Lower Hidden HIV in People on ART

  We’re testing if the drug dasatinib can help reduce the hidden HIV reservoir in people on effective ART.

  Recruiting at 3 sites Phase 1 National Institute of Allergy and Infectious Diseases (NIAID) · Chicago, Illinois and 2 other locations · NCT07342491

• Finding missed HIV testing opportunities in general practice

  This project will see how often general practice doctors missed chances to offer HIV tests to adults diagnosed with HIV in France between January 1, 2021 and July 30, 2024.

  Recruiting University Hospital, Strasbourg, France · Strasbourg · NCT07303114

• Cabotegravir for HIV-exposed newborns

  This study tests cabotegravir in newborns exposed to HIV to see if a preventive regimen is safe and tolerable.

  Recruiting Phase 1/2 ViiV Healthcare · Parow Valley · NCT07275606

• WeCare: a lay-delivered program to help MSM in South Africa manage mental health and HIV meds

  WeCare tests a lay coach–delivered program to see if it can improve mood and adherence to PrEP or ART among men who have sex with men in Johannesburg.

  Recruiting Emory University · Johannesburg · NCT07226323

• Same-day HPV screen-and-treat for women with HIV in La Romana

  This project will test whether offering same-day HPV screening and immediate treatment improves detection and treatment completion for Spanish-speaking women living with HIV in La Romana, Dominican Republic.

  Recruiting Columbia University · La Romana · NCT07225530

• Phase 2b testing of oral VH4524184 regimens for adults with untreated HIV‑1

  This trial will test whether two doses of a new oral medicine, VH4524184 taken with FTC/TAF, can suppress HIV‑1 as well as the standard DTG/3TC treatment in adults who have never received antiretroviral therapy.

  Recruiting at 123 sites Phase 2 ViiV Healthcare · Bakersfield, California and 122 other locations · NCT07202546

• Switching to a two-drug dolutegravir/lamivudine regimen versus staying on three-drug therapy for people with suppressed HIV

  This trial will test whether switching to a two-drug regimen (dolutegravir/lamivudine) keeps viral suppression and reduces metabolic and tolerability problems in adults with HIV who are already virologically suppressed on three-drug therapy.

  Recruiting Phase 4 Instituto Mexicano del Seguro Social · Mexico City, Mexico City · NCT07138144

• Mail-delivered mouth rinse and saliva kits for HPV testing in people with HIV

  This project tests whether people living with HIV can collect mouth rinse and saliva samples at home, mail them in, and get HPV test results that match clinic-collected samples.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07087145

• Comparing two strategies to increase HIV self-testing among social networks of PrEP clients

  This study is testing two ways to help people connected to PrEP clients get more HIV self-testing kits to see which method works better.

  Recruiting University of Miami · Miami, Florida · NCT06927856

• Tail-PrEP: Safe, guided stopping of long-acting PrEP with coaching and monitoring

  This study tests whether monthly HIV prevention coaching and drug-level monitoring can help people stop long-acting cabotegravir or switch to safer options without increasing HIV risk.

  Recruiting Columbia University · New York, New York · NCT06868641

• See if PrEP for WINGS helps with starting and sticking to PrEP among women in community supervision programs

  This study tests PrEP for WINGS plus PrEP compared with PrEP alone to see if it increases PrEP initiation and adherence among cisgender women in CSPs who use alcohol hazardously and may face IPV and HIV risk.

  Recruiting Columbia University · New York, New York · NCT06853314

• Reducing alcohol use and improving HIV treatment for men in fishing communities

  This study is testing a new program to help men with HIV in fishing communities cut down on drinking and stick to their HIV treatment to improve their health.

  Recruiting San Diego State University · Kampala · NCT06771843

• Evaluating a tailored healthcare delivery model for people living with HIV and other health conditions

  This study is testing a new way to deliver healthcare for people living with HIV who also have other health issues to see if it helps them get better care.

  Recruiting Chinese University of Hong Kong · Shatin · NCT06738134

• Assessing the safety and pharmacokinetics of VH4011499 in healthy adults

  This study is testing a new drug called VH4011499 to see if it's safe and how it works in healthy adults aged 18 to 55.

  Recruiting at 2 sites Phase 1 ViiV Healthcare · Las Vegas, Nevada and 1 other locations · NCT06724640

• Examining drug interactions in older adults living with HIV

  This study looks at how different medications interact in older adults with HIV to see if we can improve their treatment plans.

  Recruiting IRCCS Azienda Ospedaliero-Universitaria di Bologna · Bologna · NCT06717581

• Hiltonol‑adjuvanted CD40.HIVRI.Env (VRIPRO) vaccine in adults who completed HVTN 706

  This will test whether three doses of a vaccine candidate (CD40.HIVRI.Env with Hiltonol) are safe and boost immune responses in healthy adults who previously took part in HVTN 706.

  Recruiting at 4 sites Phase 1 National Institute of Allergy and Infectious Diseases (NIAID) · San Francisco, California and 8 other locations · NCT06665646

• SER Familia: A family program to reduce acculturative stress and build resilience in Latino immigrant families.

  This program tests whether a six-session, community health worker–delivered family intervention can lower acculturative stress and reduce risks for substance use, intimate partner violence, HIV, depression, and anxiety among first-generation Latino immigrant parents and their 12–17-year-old children.

  Recruiting Duke University · Durham, North Carolina · NCT06627764

• Tracking vaccine responses in older adults living with HIV

  This study is testing how well a pneumonia vaccine works over time in older adults living with HIV compared to younger people, to see if age and HIV affect their immune response.

  Recruiting Phase 4 Hennepin Healthcare Research Institute · Minneapolis, Minnesota · NCT06514547

• Peer support to improve HIV treatment adherence in high-risk populations

  This study is testing whether a peer support program can help Black individuals who use substances and are living with or at high risk for HIV stick to their long-acting injectable treatments better than standard care.

  Recruiting at 2 sites University of Maryland, Baltimore · Washington D.C., District of Columbia and 1 other locations · NCT06501781

• Combining immune-enhancing antibodies and vaccines to control HIV after early infection

  This test will see if giving long-acting HIV antibodies together with therapeutic vaccines helps people who began ART during acute HIV infection control viral levels after a planned treatment interruption.

  Recruiting Phase 1 Henry M. Jackson Foundation for the Advancement of Military Medicine · Pathum Wan, Bangkok · NCT06484335

• Developing new agents to activate hidden HIV cells

  This study is testing new treatments that aim to wake up hidden HIV cells in people on antiretroviral therapy to see if it helps the immune system get rid of the virus for good.

  Recruiting University Hospital, Montpellier · Montpellier · NCT06441123

• Using a mobile app to help young people with HIV achieve viral suppression

  This study tests if a mobile app can help young people with HIV better manage their health and achieve lower virus levels.

  Recruiting at 6 sites MetroHealth Medical Center · Van Nuys, California and 6 other locations · NCT06388109

• Using male peer networks to improve HIV prevention engagement

  This study is testing whether using male friends to share HIV self-testing kits can help men in Eastern Zimbabwe get better access to HIV prevention services like PrEP.

  Recruiting University of Stellenbosch · Mutare, Manicaland Province · NCT06370923

• Comparing two treatments for cervical cancer risk reduction in women living with HIV in Mozambique

  This study is testing two different treatments for pre-cancerous cervical lesions in women living with HIV in Mozambique to see which one works better in getting rid of high-risk HPV.

  Recruiting Instituto Nacional de Saúde, Mozambique · Maputo · NCT06326294

• Testing a new long-acting treatment for HIV

  This study is testing a new long-acting injection for HIV to see if it's safe and how well it works in healthy adults.

  Recruiting at 5 sites Phase 1 ViiV Healthcare · Lenexa, Kansas and 4 other locations · NCT06310551

• Motivational interviewing for male couples to reduce drug use and HIV risk

  This study is testing whether a special conversation technique for male couples can help reduce drug use and lower the risk of HIV.

  Recruiting Hunter College of City University of New York · Detroit, Michigan and 2 other locations · NCT06307977

• Empowering Black male caregivers to support Black girls' sexual health

  This study tests a new program that helps Black male caregivers support Black girls in staying healthy and safe from STIs and sexual violence.

  Recruiting University of Illinois Chicago · Chicago, Illinois · NCT06266416

• Understanding the health changes in HIV patients over time

  This study looks at how the health of older adults with HIV changes over time to see how it affects their immune system and the risk of other health problems.

  Recruiting Centre de Recherches et d'Etude sur la Pathologie Tropicale et le Sida · Paris · NCT06258122

• Long-acting HIV prevention integrated with sexual and reproductive health services

  This study is testing if offering different long-acting HIV prevention options, like injections and vaginal rings, along with regular health services can help young people in rural South Africa stay safe from HIV.

  Recruiting Phase 3 Africa Health Research Institute · Somkele, KwaZulu-Natal · NCT06250504

• Text messaging program for HIV prevention in young men who have sex with men

  This study is testing if a text messaging program can help young men who have sex with men, aged 13-20, prevent HIV by sending them specific health messages.

  Recruiting at 2 sites Center for Innovative Public Health Research · San Clemente, California and 1 other locations · NCT06230367

• Improving HIV prevention for pregnant women in Zimbabwe

  This study is trying to improve how pregnant women in Zimbabwe can use a medicine to prevent HIV by addressing the challenges they face and getting feedback from them and their healthcare providers.

  Recruiting Massachusetts General Hospital · Harare · NCT06226155

• Peer support program to improve health for women living with HIV

  This study tests a program that combines therapy, exercise, and support from peers to help women living with HIV stick to their medications and improve their overall health.

  Recruiting University of California, San Diego · San Diego, California · NCT06216600

• Evaluating community delivery of HIV treatment for newly diagnosed individuals

  This study is testing if providing HIV treatment in community settings can help newly diagnosed individuals in Uganda stick to their care and achieve better health outcomes.

  Recruiting University of Washington · Kampala · NCT06126913

• Syringe-service telemedicine plus social-network HIV prevention program

  This program will test whether training people who inject drugs to recruit and educate their peers through syringe service telemedicine and social networks increases HIV testing and use of prevention and treatment services in Maryland.

  Recruiting Johns Hopkins University · Baltimore, Maryland and 1 other locations · NCT06103370

• Understanding how HIV treatment affects gut bacteria

  This study is trying to see how different HIV treatments affect gut bacteria in people living with HIV by looking at their stool samples before and after they change medications.

  Recruiting University of Manchester · Manchester, Greater Manchester · NCT06100211

• Text messaging program to reduce HIV risk among dental patients

  This study tests whether sending text messages about HIV prevention can help dental patients who are at risk for HIV stay safer.

  Recruiting at 2 sites Boston University · Boston, Massachusetts and 1 other locations · NCT06088277

• Improving HIV prevention and substance use in homeless youth

  This study is testing a new program called MY-RIDE to see if it can help homeless youth reduce substance use and improve their HIV prevention efforts.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06074354

• High-intensity exercise to improve cognitive function in older adults with HIV

  This study tests whether high-intensity exercise can help older adults with HIV think better and stick to their workout routines compared to regular moderate exercise.

  Recruiting at 2 sites University of Alabama at Birmingham · Birmingham, Alabama and 2 other locations · NCT06013579

• Reducing alcohol use in PrEP users through SBIRT intervention

  This study is testing if a program that helps people cut down on drinking can improve the health of those using PrEP for HIV prevention and help them stick to their medication.

  Recruiting University of Louisville · Louisville, Kentucky · NCT06005298

• Improving HIV Screening and Prevention for Adolescents in Emergency Departments

  This study is trying out a new way to offer HIV testing and prevention services to teens aged 15-21 in emergency rooms to help keep them safe from HIV.

  Recruiting Children's Hospital Medical Center, Cincinnati · Columbus, Ohio and 3 other locations · NCT06003192

• Study of gut and vaginal microbiota in women living with HIV

  This study looks at how the balance of bacteria in the vagina affects the risk of HPV infection and cervical issues in women living with HIV in China.

  Recruiting Peking Union Medical College Hospital · Beijing, Beijing Municipality · NCT05996016

• Support from traditional healers to improve HIV care in rural Uganda

  This study tests whether training traditional healers to provide support and counseling can help people with HIV in rural Uganda stick to their treatment and improve their health.

  Recruiting Weill Medical College of Cornell University · Mbarara · NCT05943548

• One-stop PrEP care model for HIV prevention in Kenya

  This study tests a new way to deliver PrEP services in public health facilities in Kenya to see if it helps more people start and stay on PrEP for HIV prevention.

  Recruiting University of Washington · Kisumu · NCT05905640

• Telehealth approach for HIV and harm prevention

  This study tests if using telehealth services can help people at risk for HIV get the medications and support they need to prevent HIV, treat hepatitis C, and manage substance use.

  Recruiting University of Miami · Miami, Florida and 1 other locations · NCT05897099

• Understanding chronic kidney disease in Sub-Saharan Africa

  This study is trying to understand how common chronic kidney disease is in Sub-Saharan Africa and what factors might be causing it by looking at the health and lifestyle of adults in the Bagamoyo district.

  Recruiting Swiss Tropical & Public Health Institute · Bagamoyo, Pwani Region · NCT05881447

• Team-based intervention for HIV care in hospitals

  This study tests if a team-based support program can help newly diagnosed HIV patients get the care they need while in the hospital and reduce their chances of coming back to the hospital.

  Recruiting Loma Linda University · Loma Linda, California · NCT05866523

• Exploring HIV risk in vulnerable youth with digital health intervention

  This study is trying to see how a digital health program can help young sexual and gender minorities reduce their risk of HIV and understand the factors that affect their prevention choices.

  Recruiting Hektoen Institute for Medical Research · Chicago, Illinois · NCT05848570

• Improving smoking cessation and HIV/TB treatment outcomes in South Africa

  This study is testing a new program to help people living with HIV and tuberculosis in Cape Town quit smoking to improve their overall health and treatment results.

  Recruiting Massachusetts General Hospital · Rondebosch · NCT05842161

• MARVIN Chatbots for Health Information

  This study is testing a new chatbot designed to provide helpful health information for people with different health conditions, like breast cancer and pediatric emergencies, to see how well it works for them.

  Recruiting at 2 sites McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec and 1 other locations · NCT05789901

• Evaluating a new HIV treatment for children

  This study is testing a new combination HIV treatment for children aged 6 to under 12 who are already managing their virus well, to see if it is safe and effective for them.

  Recruiting at 7 sites Phase 1/2 ViiV Healthcare · Long Beach, California and 7 other locations · NCT05674656

• Observational study of HIV-positive individuals receiving long-acting antiretroviral therapy

  This study is looking at how well long-acting HIV medications work for people living with HIV and how they affect their overall health and quality of life over 48 weeks.

  Recruiting IRCCS San Raffaele · Milan · NCT05663580

• Comparing different support methods for treating drug-resistant tuberculosis and HIV in South Africa

  This study is testing four different ways to help adults with drug-resistant tuberculosis and HIV stick to their treatment plans to see which method works best.

  Recruiting Columbia University · Durban, KwaZulu-Natal · NCT05633056

• Improving HIV testing and care for men using U=U messaging

  This study is testing if using U=U messaging can help more men in South Africa get tested for HIV, start treatment, and stay healthy.

  Recruiting at 2 sites Desmond Tutu HIV Foundation · East London, Eastern Cape and 1 other locations · NCT05602376

• Using a mobile app to reduce risky alcohol use and HIV risk

  This study is testing a mobile app that sends real-time messages to help people reduce risky drinking and lower their chances of HIV by encouraging safer choices when they visit certain locations.

  Recruiting at 2 sites University of Kentucky · New Haven, Connecticut and 1 other locations · NCT05576350

• Lowering cholesterol and inflammation in HIV patients using Bempedoic acid

  This study is testing if a medication called Bempedoic acid can lower cholesterol and inflammation in people over 40 with HIV who have heart disease or are at risk for it.

  Recruiting at 3 sites Phase 2 University of California, San Francisco · Los Angeles, California and 2 other locations · NCT05488431

• Investigating a new long-acting HIV treatment in healthy adults

  This study is testing a new long-acting HIV treatment in healthy adults to see how safe it is and what the best dose might be for future use.

  Recruiting at 2 sites Phase 1 ViiV Healthcare · Orlando, Florida and 2 other locations · NCT05418868

• Evaluating management strategies for HIV treatment failure in Sub-Saharan Africa

  This study is testing different treatment options for people with HIV in Uganda and South Africa who aren't responding well to their current medication, to see which approach helps them lower their viral load the best.

  Recruiting at 3 sites Massachusetts General Hospital · Durban and 2 other locations · NCT05373758

• Observing HIV infection risks among high-risk individuals in Vienna

  This study looks at the risk factors for new HIV infections among HIV-negative men who have sex with men and transgender individuals in Vienna to better understand how the virus spreads in these groups.

  Recruiting Medical University of Vienna · Vienna · NCT05326061

• Peer-driven intervention to prevent HIV, HCV, and drug overdoses among people who inject drugs

  This study is testing whether getting support and education from peers can help people who inject drugs reduce their risk of HIV, hepatitis C, and overdoses.

  Recruiting Johns Hopkins Bloomberg School of Public Health · Baltimore, Maryland · NCT05320835

• Changes in HIV reservoir, inflammation, and gut microbiome after switching to long-acting injectable versus staying on oral integrase-based therapy

  This project will try to see if switching people living with HIV who are virologically suppressed to long-acting injectable therapy changes their immune activation, HIV reservoir, or gut microbiome compared with those who remain on oral integrase-based regimens.

  Recruiting Hôpital Européen Marseille · Marseille · NCT05303337

• Using probiotics to reduce heart disease risk in people with HIV who drink heavily

  This study is testing if a probiotic pill can help improve gut health and lower heart disease risk in people with HIV who drink heavily.

  Recruiting Phase 2 Vanderbilt University Medical Center · Nashville, Tennessee · NCT05288790

• Investigating the HIV Infected Reservoir to Find a Cure

  This study is trying to find ways to cure HIV by looking at the hidden virus in the blood of different groups of people living with HIV.

  Recruiting Erasmus Medical Center · Rotterdam · NCT05215704

• Observational cohort study of HIV and other infections

  This study is looking to see how many new HIV infections happen among people aged 14-55 who are at risk, while also checking for other STIs and helping those diagnosed with HIV get the right treatment.

  Recruiting at 2 sites Henry M. Jackson Foundation for the Advancement of Military Medicine · Kericho, Kericho County and 3 other locations · NCT05147519

• Exploring gut microbiota and frailty in older people living with HIV

  This study looks at how changes in gut bacteria might affect older adults with HIV in terms of frailty and other health issues over five years.

  Recruiting Hôpital Européen Marseille · Marseille · NCT05078957

• Long-acting injectable treatment for HIV in young women

  This study is testing a long-acting injectable treatment for HIV in young women to see if it works better than standard pills and helps improve their health and prevent unintended pregnancies.

  Recruiting University of Alabama at Birmingham · Eldoret, Kenya · NCT05044962

• Text messaging versus a smartphone app to help people take PrEP

  This project will see if weekly text messages or a smartphone app better help cisgender and transgender men who have sex with men and transgender women take daily PrEP as prescribed.

  Recruiting at 3 sites Public Health Foundation Enterprises, Inc. · San Francisco, California and 3 other locations · NCT04855773

• Observing the effects of antiretroviral therapy in HIV/AIDS patients

  This study is trying to see how well antiretroviral therapy works for people with HIV/AIDS and what side effects they might experience over time.

  Recruiting Guangzhou 8th People's Hospital · Guangzhou, Guangdong · NCT04667026

• Determining the optimal number of counseling sessions to improve HIV treatment adherence

  This project will test how many behavioral counseling sessions help people with HIV who are not reliably taking ART to improve and maintain medication adherence and viral suppression.

  Recruiting at 2 sites University of Connecticut · Storrs, Connecticut and 1 other locations · NCT04577313

• Dual combination therapy for HIV-1 infected patients

  This study tests if a new combination of two HIV medications can help people who have their virus under control feel better and avoid side effects from their current treatment.

  Recruiting Phase 2 Centre de Recherches et d'Etude sur la Pathologie Tropicale et le Sida · Paris, Île-de-France Region · NCT04513626

• Effects of exercise on cardiovascular responses in people living with HIV/AIDS

  This study is testing whether regular exercise can improve heart and blood pressure responses in people living with HIV/AIDS who have trouble exercising.

  Recruiting Instituto Nacional de Cardiologia de Laranjeiras · Rio de Janeiro, Rio de Janeiro · NCT04512456

• Investigating Autophagy in HIV-Infected Patients on Antiretroviral Therapy

  This study is testing how well certain immune cells work in people with HIV who are on treatment, compared to healthy individuals, to see if problems with a process called autophagy are linked to ongoing inflammation.

  Recruiting Centre Hospitalier Régional d'Orléans · Orléans · NCT04160455

• Understanding muscle fatigue in older individuals with and without HIV

  This study is trying to see how muscle problems affect exercise fatigue in older adults with and without HIV.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT04142047

• Examining frailty in older individuals living with HIV

  This study looks at how frailty affects older people living with HIV in Hong Kong to see how it relates to their health, quality of life, and risk of dying over ten years.

  Recruiting Chinese University of Hong Kong · Shatin · NCT03413683

• Evaluating the Yellow Fever Vaccine in People with HIV

  This study is testing how well the Yellow Fever vaccine works and how safe it is for people with HIV compared to those without HIV.

  Recruiting Phase 4 Oswaldo Cruz Foundation · Rio de Janeiro · NCT03132311

• Understanding how HIV medications work in pregnant women

  This study is testing how HIV medications work in pregnant women during the third trimester to see if we can improve their treatment.

  Recruiting at 16 sites Radboud University Medical Center · Brussels and 20 other locations · NCT00825929

• Understanding early HIV infections in Zurich

  This study looks at how early HIV infections affect people's health and how starting treatment right away can change the course of the disease for those newly diagnosed in Zurich.

  Recruiting University of Zurich · Zurich · NCT00537966

• Long-term follow-up of HIV-infected patients

  This study looks at how well different HIV treatments work and their long-term effects on the health and quality of life of people living with HIV.

  Recruiting The HIV Netherlands Australia Thailand Research Collaboration · Bangkok · NCT00411983

• Registry to monitor the effects of antiretroviral drugs during pregnancy

  This study is trying to see if certain HIV medications taken during pregnancy can cause any serious problems for the baby.

  Recruiting Syneos Health · Wilmington, North Carolina · NCT00404989

• Observational study of HIV-1 infected individuals and their responses to treatment

  This study is looking at how HIV-1 affects people and how they respond to treatment by collecting health information and samples from volunteers to learn more about the virus and drug resistance.

  Recruiting University of California, San Francisco · San Francisco, California · NCT00187512

NIH-funded research (1)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Investigating treatments and prevention strategies for HIV in children and adolescents

  This study is looking for better ways to treat HIV and its effects in babies, kids, teens, and pregnant women, so they can live healthier lives, especially by preventing the virus from passing from mothers to their children.

  NIH research Westat, INC. · Rockville, United States · NIH-10369859

Related topics

Quick answers

How many HIV Infections clinical trials are recruiting right now?

97, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 37 countries. The most sites are in United States (44 trials), South Africa (8 trials), France (8 trials), Uganda (6 trials), Brazil (5 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 9, Phase 1/2: 4, Phase 2: 4, Phase 4: 3. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →