Comparing two strategies to increase HIV self-testing among social networks of PrEP clients
Test-to-PrEP: A Randomized Hybrid Implementation/Effectiveness Trial of a Social Network Strategy to Increase Equitable Reach of HIV Testing and PrEP Information
NA · University of Miami · NCT06927856
This study is testing two ways to help people connected to PrEP clients get more HIV self-testing kits to see which method works better.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 320 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Miami (other) |
| Locations | 1 site (Miami, Florida) |
| Trial ID | NCT06927856 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the effectiveness of two different social network strategies—direct distribution and referral-based distribution—in enhancing the completion rates of HIV self-testing (HIVST) among individuals connected to current Pre-Exposure Prophylaxis (PrEP) clients. Participants, known as 'Egos', will identify peers in their social networks who may benefit from HIVST kits and PrEP information. The study will involve PrEP clients who are currently receiving treatment and their identified peers, referred to as 'Alters'. The goal is to improve access to HIV testing and prevention methods within these networks.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals currently prescribed PrEP who can identify members of their social network that may benefit from HIVST.
Not a fit: Patients who are unable to provide informed consent or identify potential peers for the study may not receive any benefit.
Why it matters
Potential benefit: If successful, this study could significantly increase the rates of HIV self-testing and PrEP uptake among at-risk populations.
How similar studies have performed: Other studies have shown success in using social network strategies to improve health outcomes, suggesting this approach may be effective.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria - PrEP Clients (Egos): * Stated willingness to provide informed consent. * Stated willingness to comply with all study procedures. * Stated availability for the duration of the study. * Ability to identify members of their social network who may benefit from receiving an HIVST kit and PrEP information. * Currently prescribed PrEP by RAPID clinics, including those initiating PrEP on the same day as study enrollment. Inclusion Criteria for Peers (Alters): \- Provision of electronic informed consent prior to completion of the Quick Response (QR)-linked survey instruments. Exclusion Criteria for PrEP Clients (Egos): * Inability or refusal to provide informed consent (e.g., cognitive impairment). * Unable or unwilling to comply with study procedures per study investigator * Inability to identify members of their social network who may benefit from receiving an HIVST kit and PrEP information. * Aged 17 years or younger. Exclusion Criteria for Peers (Alters): * Failure to provide electronic informed consent prior to starting QR-linked Alter survey tools. * Age 17 years or younger.
Where this trial is running
Miami, Florida
- University of Miami — Miami, Florida, United States (RECRUITING)
Study contacts
- Principal investigator: Susanne Dobleck-Lewis, MD — University of Miami
- Study coordinator: Susanne Doblecki-Lewis, MD
- Email: SDoblecki@med.miami.edu
- Phone: 3052434037
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: HIV Infections